Thiostrepton inhibits growth and induces apoptosis by targeting FoxM1/SKP2/MTH1 axis in B-precursor acute lymphoblastic leukemia cells حسب Kuttikrishnan, Shilpa

"…Thiostrepton led downregulation of FoxM1 accompanied by decreased expression of Aurora kinase A, B, matrix metalloproteinases, and oncogene SKP2 as well as MTH1. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Dietary L-carnitine and vitamin-E; a strategy to combat ochratoxin-A induced immunosuppression حسب Bhatti S.A.

"…One-day old white male Leghorn chicks were divided into 12 groups, having 20 birds each and were offered ration contaminated with OA (1.0 or 2.0 mg/kg feed) alone and concurrently with LC (1.0 g/kg) and/or VE (0.2 g/kg), for 42 days. …"
احصل على النص الكامل
احصل على النص الكامل

Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation حسب El Hasasna, Hussain

"…We demonstrated that Rhus coriaria ethanolic extract (RCE) inhibits the proliferation of these cell lines in a time- and concentration-dependent manner. RCE induced senescence and cell cycle arrest at G1 phase. …"
احصل على النص الكامل
احصل على النص الكامل

A Reverse MultipleChoice Based mLearning System حسب Karkar, AbdelGhani

"…For each of one or more of the incorrect answers, a follow-up query is generated for which the incorrect answer is correct. …"
احصل على النص الكامل
احصل على النص الكامل

Zebrafish larvae as a model to demonstrate secondary iron overload. حسب Nasrallah, Gheyath K

"…The three assays showed that iron treatment alone resulted in a significant increase in total iron. Deferoxamine treatment of the iron-loaded zebrafish larvae showed a significant decrease in total iron concentration. …"
احصل على النص الكامل
احصل على النص الكامل

Structural and magnetic properties of Ni1-xZnxFe 2O4 (x=0, 0.5 and 1) nanopowders prepared by sol-gel method حسب Gao P.

"…A series of nanostructured Ni-Zn ferrites Ni1-xZn xFe2O4 (x=0, 0.5 and 1) with a grain size from 24 to 65 nm have been prepared with a sol-gel method. …"
احصل على النص الكامل
احصل على النص الكامل

Synthesizing New Anodes From Qatalum's 1st Cut Spl حسب Hani Holozadah, Abdullah

"…For comparison, the anodes were synthesized using the extracted graphite material from the 1st cut SPL, a commercial one and a petroleum coke (PC). …"
احصل على النص الكامل
احصل على النص الكامل

Mossbauer Effect Study of the Cations Distribution and its Influence on the Electric Field Gradient of the Cdx Co1-x Ferrite System حسب Eissa, N. A. [نبيل عيسى]

"…In the ferrite system Cd,Co,_x Fe; 04 (X=0.0, O.I, 0.2, ....... , 1.0). it was found that the introduction of Co2'1' decrease the EFG at the octahedral B-site. …"
احصل على النص الكامل

Effect of hyperlipidemia on ketoconazole-midazolam drug-drug interaction in rat حسب Hamdy, D. A.

احصل على النص الكامل
احصل على النص الكامل

Flavonoids in adipose tissue inflammation and atherosclerosis: One arrow, two targets حسب Fardoun, Manal Muin

احصل على النص الكامل
احصل على النص الكامل

The role of type II FB (I):Tl+ defect in laser light generation and color image formation at the low coordination surface sites of AgBr: Ab initio calculations حسب Shalabi, A.S.

"…All relaxed excited states of the defect containing surfaces were deep below the lower edges of the conduction bands of the ground-state defect-free surfaces indicating that type II FB(I):Tl+ is suitable laser defect. The probability of orientational destruction of the two centers, attributed to the assumed saddle point ion configurations along the 〈1 1 0〉 axis, was found to decrease as the coordination number of the surface ions decreases. …"
احصل على النص الكامل
احصل على النص الكامل

Effects of gamma radiation on the activity of the, mosquito culex pipiens L. : I. Effects on the attraction of the mosquito to light, colours and host حسب Wakid, A. M. [عبد الفتاح مجاهد واكد]

احصل على النص الكامل

Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats. حسب Tan, Yong Chia

"…CsA increased blood pressure (by 46mmHg) and decreased creatinine clearance (by 49%, all P<0.05). …"
احصل على النص الكامل
احصل على النص الكامل

Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens حسب Bhatti, Sheraz Ahmed

"…Ochratoxin A (OTA), an important fungal metabolite in foods and feeds has been shown to induce oxidative stress and cellular injuries to human and animal subjects. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The effect of acute ophiobolin A treatment on HO-mediated inflammatory processes حسب Posa, Aniko

"…We found that OPA caused a significant elevation in the concentrations of IL-6 and TNF-, increased MPO activity and decreased HO enzyme activity in the plasma. …"
احصل على النص الكامل
احصل على النص الكامل

Qatar University culture collection: A source of biodiversity and numerous applications حسب Al Ghazal, Ghamza

"…During their phases of growth, they produce a variety of metabolites such as lipids, proteins and carbohydrates in large amounts over a short period of time. …"
احصل على النص الكامل
احصل على النص الكامل

Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain حسب Mohammad H., Merii

"…In addition, nicotine individually decreased expression levels of all examined protein targets, significantly for CYP1B1 (p < 0.001), CYP19A1 (p = 0.010), AhRR (p = 0.042), and ARNT (p < 0.001), compared to control. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes حسب Younes, Noura B.

"…Methods: The objective of this study was to test the effects of DHA on the hypoxia responses (1.0 % for 24 hours) of 3T3-L1 adipocytes with a focus on oxidative stress, inflammation, and mitochondrial function, and antioxidant status. …"
احصل على النص الكامل

A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... حسب Thirumal Kumar, D

"…The molecular interaction study also revealed that the co-crystallized AKT1 inhibitor N-(4-(5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)-3H-imidazo [4,5-b]pyridin-3-yl)benzyl)-3-fluorobenzamide (12j) exhibited a better interaction with native AKT1 compared with the E17K mutant AKT1 protein, whereas, Akti-1/2 exhibited the opposite effects, i.e., a better interaction with the E17K mutant AKT1 than the native AKT1. …"
احصل على النص الكامل
احصل على النص الكامل

Comparative skull analysis suggests species-specific captivity-related malformation in lions (Panthera leo) حسب Saragusty, Joseph

"…Lion (Panthera leo) populations have dramatically decreased worldwide with a surviving population estimated at 32,000 across the African savannah. …"
احصل على النص الكامل
احصل على النص الكامل