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point decrease » point increase (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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1001
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1002
TUDCA decreases MPO with improved mitochondrial biogenesis, mitochondria-ER contact, and alveolar formation of HOX neonatal rat lungs.
Published 2022“…The increased RAC (7.3±0.8 <i>vs</i>. 4.6±0.6) and secondary septation (34.5±3.0 <i>vs</i>. 24.8±1.1) with decreased MLI (65.1±2.9 μm <i>vs</i>. 82.3±8.4 μm) and increased capillary area (12.9±1.2% <i>vs</i>. 10.5±0.9%) demonstrate a protective effect of TUDCA to the HOX neonatal lungs (n = 6, p<0.05, 3 for each sex). *: p<0.05.…”
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1003
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1004
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1005
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1006
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1007
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1008
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1009
Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen.
Published 2023“…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”
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1010
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1011
GF mice have decreased levels of innate and adaptive immune effectors at the ocular surface.
Published 2016“…<p>A. Significantly decreased levels of complement proteins at the ocular surface in GF mice compared to SPF mice. …”
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1012
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1013
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1014
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1015
Dexamethasone decreases PGC-1α protein expression and transcription.
Published 2016“…<p>(A) Treatment of L6 myotubes with Dex (100nM, 48hrs) decreased PGC-1α protein expression (p = 0.01). n = 3/treatment from 3 experiments. …”
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1016
Dexamethasone decreases CRTC1 and CRTC2 nuclear localization.
Published 2016“…<p>Treatment of L6 myotubes with Dex (100nM, 48hrs) decreased (A) total CRTC1 (p = 0.004 and CRTC2 protein (p = 0.0007). n = 9/treatment from 3 experiments. …”
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1017
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1018
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1019
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1020