Acetylated HIF-2α regulates Cbp-mediated stress remodeling. by Rui Chen (95310)

“…Comparison of samples within a given condition was performed by one-tailed unpaired t test with decreased samples noted (*, P<0.05). …”

DataSheet_1_JNK Signaling Pathway Mediates Acetaminophen-Induced Hepatotoxicity Accompanied by Changes of Glutathione S-Transferase A1 Content and Expression.docx by Chenxi Shi (7407551)

“…The results showed that JNK signaling pathway was activated by APAP in a dose-dependent manner. C-Jun N-terminal kinase inhibitor decreased JNK and c-Jun activation significantly (P < 0.01) at 175 mg·kg⁻¹ APAP dose, and phosphorylation levels of upstream proteins of JNK were also decreased markedly (P < 0.05). …”

DataSheet_1_Corilagin Ameliorates Con A-Induced Hepatic Injury by Restricting M1 Macrophage Polarization.zip by Fenglian Yan (6322787)

“…The expression of M1 macrophage-associated proinflammatory cytokines and genes, including interleukin (IL)-6, IL-12, and inducible nitric oxide synthase (iNOS), was also decreased after corilagin treatment. …”

Percent of weeks with complete submissions for all sets of team forecasts, scaled, pairwise relative Weighted Interval Score (rWIS; see <i>Methods</i> for description), observed 95... by Velma K. Lopez (18510171)

Data Sheet 1_Comprehensive analysis of metabolism-related genes in sepsis reveals metabolic–immune heterogeneity and highlights GYG1 as a potential therapeutic target.csv by Jie Zheng (31208)

“…Machine learning identified five hub metabolic genes for constructing a metabolic risk score, whose prognostic relevance was robustly validated in an external cohort. …”

Image1_Effects of winter pulsed warming and snowmelt on soil nitrogen cycling in agricultural soils: A lysimeter study.JPEG by Danielle Green (522450)

“…We monitored the subsurface soil temperature, moisture, and porewater geochemistry together with air temperature, precipitation, and N₂O fluxes in four agricultural field-controlled lysimeter systems (surface area of 1 m² and depth of 1.5 m) at the University of Guelph’s Elora Research Station over one winter (December 2020 to April 2021). …”

Image_1_Efficiency and Toxicity of Ruxolitinib as a Salvage Treatment for Steroid-Refractory Chronic Graft-Versus-Host Disease.tif by Dong Wang (73290)

“…Patients who achieved a CR and PR achieved better survival outcomes (84.5%, 73.9–95.1%, 95% CI) than those who showed NR to ruxolitinib treatments (16.7%, 0–34.3%, 95% CI) (P<0.001). …”

Table_1_Identification and Validation of a Urinary Biomarker Panel to Accurately Diagnose and Predict Response to Therapy in Lupus Nephritis.docx by Laura Whittall-Garcia (12696611)

“…</p>Results<p>Twenty-one patients were included in stage 1. Twelve (57.1%), 4 (19.1%), and 5 (23.8%) patients had a complete (CR), partial (PR) and no (NR) remission at 24 ± 3 months, respectively. …”

Table_1_Efficiency and Toxicity of Ruxolitinib as a Salvage Treatment for Steroid-Refractory Chronic Graft-Versus-Host Disease.docx by Dong Wang (73290)

“…Patients who achieved a CR and PR achieved better survival outcomes (84.5%, 73.9–95.1%, 95% CI) than those who showed NR to ruxolitinib treatments (16.7%, 0–34.3%, 95% CI) (P<0.001). …”

Table_1_First Sprayable Double-Stranded RNA-Based Biopesticide Product Targets Proteasome Subunit Beta Type-5 in Colorado Potato Beetle (Leptinotarsa decemlineata).XLSX by Thais B. Rodrigues (11722562)

“…Laboratory assays with second instar larvae fed Ledprona showed a dose–response where 25×10⁻⁶g/L of dsPSMB5 caused 90% mortality after 6days of initial exposure. …”

Image_1_First Sprayable Double-Stranded RNA-Based Biopesticide Product Targets Proteasome Subunit Beta Type-5 in Colorado Potato Beetle (Leptinotarsa decemlineata).JPEG by Thais B. Rodrigues (11722562)

“…Laboratory assays with second instar larvae fed Ledprona showed a dose–response where 25×10⁻⁶g/L of dsPSMB5 caused 90% mortality after 6days of initial exposure. …”

Table_1_First Sprayable Double-Stranded RNA-Based Biopesticide Product Targets Proteasome Subunit Beta Type-5 in Colorado Potato Beetle (Leptinotarsa decemlineata).XLSX by Thais B. Rodrigues (11722562)

“…Laboratory assays with second instar larvae fed Ledprona showed a dose–response where 25×10⁻⁶g/L of dsPSMB5 caused 90% mortality after 6days of initial exposure. …”

Image_1_First Sprayable Double-Stranded RNA-Based Biopesticide Product Targets Proteasome Subunit Beta Type-5 in Colorado Potato Beetle (Leptinotarsa decemlineata).JPEG by Thais B. Rodrigues (11722562)

“…Laboratory assays with second instar larvae fed Ledprona showed a dose–response where 25×10⁻⁶g/L of dsPSMB5 caused 90% mortality after 6days of initial exposure. …”

Sleep in Dolphins: A Difficult Case? by Chiara Cirelli (49454)

“…In fact, the presence of slow waves in one hemisphere is associated with unilateral slow waves in the thalamus, and unilateral decrease in brain metabolism, including in the ipsilateral locus coeruleus, an arousal-promoting system [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0060216#pbio-0060216-b124" target="_blank">124</a>]. …”

DataSheet1_A novel Vision Zero leadership training model to support collaboration and strategic action planning.docx by Rebecca B. Naumann (6651305)

“…We measured confidence in a range of skills (on a 5-point scale, 1: not confident to 5: very confident). …”

Data_Sheet_1_The Salvinorin Analogue, Ethoxymethyl Ether Salvinorin B, Promotes Remyelination in Preclinical Models of Multiple Sclerosis.PDF by Kelly F. Paton (3934061)

“…In the experimental autoimmune encephalomyelitis model, we found that EOM SalB (0.1–0.3 mg/kg) effectively decreased disease severity in a KOR-dependent manner and led to a greater number of animals in recovery compared to U50,488 treatment. …”

Fig 4 - by Mateus Marques Bueno (6699737)

“…<i>parahyba</i> (A), <i>C</i>. <i>myrianthum</i> (B) and <i>C</i>. …”

Effect of CXB and DMC combinations on P-glycoprotein protein content and activity of P-glycoprotein in HeLa (A) and SiHa cells (B). by Diana Xochiquetzal Robledo-Cadena (5265959)

R117H-7T and R117H-5T function (+/-) ivacaftor: estimates from <i>in vitro</i> measurements of channel function and transcript analysis. by Jessica E. Char (476386)

“…(B) R117H-5T. The 5T mutation causes a large decrease in full-length transcripts and when combined with R117H reduces function to ~1.5% (column 3) and to 0.75% when the other allele is non-functional (column 4). …”

Demographic analysis of the lifespan in <i>zprogerin</i> and <i>zprelamin A</i> transgenic zebrafish. by Eriko Koshimizu (53194)

“…In z<i>progerin</i> transgenic zebrafish (Progerin Tg), two independent cohorts (Cohort 1 and 2) were analyzed and the survival curves show significant decreases in lifespan compared with the corresponding wild-type siblings (Non-Tg siblings). z<i>Prelamin A</i> transgenic zebrafish (Prelamin Tg) also showed a relatively shorter lifespan than their siblings (Non-Tg siblings).…”