The GTPase RalA Regulates Different Steps of the Secretory Process in Pancreatic β-Cells by Sanda Ljubicic (257524)

“…Real-time measurements by fluorescence resonance energy transfer revealed that RalA activation in response to secretagogues occurs within 3–5 min and reaches a plateau after 10–15 min. …”

Data_Sheet_1_Personalized dietary advices provided by a dietitian increase calcium intake in outpatients with multiple sclerosis—Results from a randomized, controlled, single-blind... by Sandrine Fiorella (14434197)

“…Background and aims<p>Multiple sclerosis (MS) is associated with osteoporosis, possibly due to neurological disability and decreased calcium intake. The objective of this study was to evaluate the efficacy of a personalized nutritional advice program by a dietitian compared to the delivery of a standard advice form to optimize dietary calcium intake in outpatients with MS.…”

RECQL4 functions in a separate pathway from REV1 and is degraded following DNA crosslinks. by Thong T. Luong (13833935)

Evolution of hepatitis A virus seroprevalence among HIV-positive adults in Taiwan by Yu-Lin Lee (4515169)

“…<div><p>Objectives</p><p>The study aimed to describe the seroprevalence of hepatitis A virus (HAV) in HIV-positive adult patients in Taiwan between 2012 and 2016 and to examine the evolution of HAV seroprevalence between 2004–2007 and 2012–2016.…”

Efficacy and safety of lorcaserin in obesity: a systematic review and meta-analysis of randomized controlled trials by Awadhesh Kumar Singh (6174640)

“…</p> <p><b>Results</b>: The meta-analysis of four RCTs (N = 16,856) demonstrated a significant decrease in body weight (mean ∆ −3.076 Kg; 95% CI, −3.49 to −2.66; P < 0.00001), compared to placebo. …”

Glyphosate alters the composition, but not density, of the <i>A</i>. <i>gambiae</i> midgut microbiota. by Daniel F. Q. Smith (10788903)

“…Error bars represent the mean and ±SD. <b>(B)</b> Glyphosate alters the composition of the mosquito microbiota, leading to decrease of Entereobacteriacae and an increase of <i>Asaia</i> spp. …”

Structural and functional analysis of cell-free produced PfAQP without a GFP fusion. by Annika Müller-Lucks (147176)

“…Changes in the light scattering intensity reflect liposome shrinkage due to water efflux (increase in light scattering) and liposome swelling due to glycerol plus secondary water influx (decrease in light scattering). Note the difference of the scale of the abscissae as a consequence of lower glycerol permeability by at least one order of magnitude. …”

Disease course of Chronic Relapsing Inflammatory Optic Neuropathy (CRION) in a single care center by Luis Enrique MOLINA-CARRIÓN (12687286)

“…Currently, all patients are on maintenance treatment with mycophenolate mofetil or rituximab with a decrease in relapsing rate. Conclusions: Diagnosis of CRION is challenging and should be kept in mind. …”

SapA is required for NTHI to directly counter host defensin lethality <i>in vivo.</i> by Catherine L. Shelton (340365)

“…Black and gray horizontal lines (panels A and B) represent the geometric mean value of each cohort (n = 5 animals per cohort). …”

DataSheet_1_The Spleen as a Target to Characterize Immunomodulatory Effects of Down-Stream Processed Cyberlindnera jadinii Yeasts in Atlantic Salmon Exposed to a Dietary Soybean Me... by Byron Morales-Lange (5337284)

“…In order to characterize immunomodulatory properties of novel functional ingredients, this study used four diets, one based on FM, a challenging diet with 40% soybean meal (SBM), and two diets containing 40% SBM with 5% of Cyberlindnera jadinii yeast exposed to different down-stream processing conditions: heat-inactivated (ICJ) or autolysation (ACJ). …”

DataSheet_2_The Spleen as a Target to Characterize Immunomodulatory Effects of Down-Stream Processed Cyberlindnera jadinii Yeasts in Atlantic Salmon Exposed to a Dietary Soybean Me... by Byron Morales-Lange (5337284)

“…In order to characterize immunomodulatory properties of novel functional ingredients, this study used four diets, one based on FM, a challenging diet with 40% soybean meal (SBM), and two diets containing 40% SBM with 5% of Cyberlindnera jadinii yeast exposed to different down-stream processing conditions: heat-inactivated (ICJ) or autolysation (ACJ). …”

Mechanical properties of MoS₂ nanotubes under tension: a molecular dynamics study by Sergio Mejía-Rosales (10129116)

The BCM rule feedforward connection shows a hysteresis in pre- and postsynaptic stimulation. by Michael Fauth (683879)

“…For each stimulation, the average number of synapses was calculated separately for the in- and decreasing direction and later averaged over all stimulation cycles (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004031#sec004" target="_blank">Methods</a>). …”

<i>Varroa destructor</i> occurrence is linked to regional, temporal and climatic variables. by Alison McAfee (1392388)

“…</b> A & B) Fitted <i>Varroa</i> occurrence probabilities (1 = present, 0 = absent) vary by significant year (χ² = 6.5, df = 1, p = 0.001) and a date-by-region interaction (χ² = 29.6, df = 7, p < 0.001), among other influential factors. …”

Potential signatures of adaptive introgression at <i>SLC30A9</i>. by Ana Roca-Umbert (17041620)

“…Each column corresponds to a polymorphic position with a homozygous genotype in the Denisovan (112 in total; see details in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010950#pgen.1010950.s042" target="_blank">S4</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010950#pgen.1010950.s043" target="_blank">S5</a> Tables), each row is a phased haplotype, colored according to the population of origin of the individuals shown in the top. …”

Rad51 paralogs and the risk of unselected breast cancer: A case-control study by Peter Grešner (3533093)

“…In <i>Xrcc3</i>, the ⁴⁵⁴¹A/⁹⁶⁸⁵A haplotype was found to be significantly associated with reduced BrC risk (OR = 0.5; 95% CI: 0.3–0.9; p<0.05). …”

Supplementary Material for: Heme Oxygenase Activity and Heme Binding in a Neonatal Mouse Model by Kourula S. (4444969)

“…Twenty-four hours after exposure to 60 µM FH, a decrease in viability of 80% was found, compared with no decrease after exposure to 60 µM MHA. …”

Effects of the presence of stabilimentum concerning prey vibration acting in the direction tangent to the spiral threads. by G. Greco (7636232)

“…In general, the presence of stabilimentum is associated with a marginal decrease of time necessary for the output points between the web center and the prey to achieve the displacement threshold but allow the opposing threads to achieve the threshold levels, whenever stabilimentum is present between the prey and the web center. …”

Data_Sheet_1_A Novel CD3G Mutation in a Taiwanese Patient With Normal T Regulatory Function Presenting With the CVID Phenotype Free of Autoimmunity—Analysis of all Genotypes and Ph... by Wen-I Lee (474051)

“…This patient had the common variable immunodeficiency (CVID) phenotype and received regular immunoglobulin infusions over 20-years; he gradually developed nodular regenerative hyperplasia over a 5-year period. Distinct from the previously reported CD3G mutations, which mainly present as autoimmunity, the novel CD3G deletion (c.del213A) in our patient caused an obvious decrease in switched memory B cells and diminished CD40L expression. …”

Internal Thoracic Impedance - A Useful Method for Expedient Detection and Convenient Monitoring of Pleural Effusion by Gideon Charach (731133)

“…Prominent changes were observed in the respiratory rate of the study group: there was a decrease from 31.2±4.0 to 19.5±2.4 ohm (35.2%) compared to no change for the controls, and a mean increase from 83.6±5.3%-92.5±1.6% (13.2%) in O2 saturation compared to 94.2±1.7% for the controls. …”