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381
Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
Published 2019“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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382
Correlated decay of triplet excitations in the shastry-sutherland compound SrCu2 (BO3)2
Published 2014“…The temperature dependence of the gapped triplet excitations (triplons) in the 2D Shastry-Sutherland quantum magnet SrCu2(BO3)2 is studied by means of inelastic neutron scattering. …”
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383
A Prospective Association of Nut Consumption with Cognitive Function in Chinese Adults aged 55+ _ China Health and Nutrition Survey.
Published 2018“…The unadjusted cognitive score decreased by 0.29 (95% CI 0.22-0.28) with one-year aging during 1997-2006. …”
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384
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385
A Review of Pharmacogenetics of Antimalarials and Associated Clinical Implications
Published 2017“…Lumefantrine concentrations were also influenced by ABCB1 variants in the presence of nevirapine. The most critical pharmacogenetic consideration identified was the association of glucose-6-phosphate dehydrogenase deficiency with development of hemolytic anemia and decreased hemoglobin levels in patients treated with primaquine or a combination of chlorproguanil-dapsone-artesunate. …”
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386
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Prospects of Biocrude Production Potential from Local Diatom
Published 2020“…After 7 days of growth, the final biomass density reached 0.52 g/L, and average biomass productivity was 6.7 g/m2/d. Next, Nitzchia reversa was harvested using a 25 m2 crossflow filtration membrane module. …”
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390
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391
Experimental results and modelling of corrosion-damaged concrete beams strengthened with externally-bonded composites
Published 2018“…This paper presents the results of 3D finite element (FE) modelling of corrosion-damaged reinforced concrete (RC) beams strengthened in flexure with externally-bonded composites. …”
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392
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393
Hybrid fuzzy sliding mode for stick-slip suppression in drill string systems
Published 2022“…Stick-slip vibration is one of the main factors that contribute greatly to reducing the service life of drill string equipment and decreasing the efficiency of the overall drilling system. …”
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394
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398
Effects of rutile-TiO2 nanoparticles on accelerated weathering degradation of poly(Lactic Acid)
Published 2020“…The molecular weight of the weathered samples decreased due to chain scission during the degradation processes. …”
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399
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