Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach حسب P., Sneha

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Inhibition of p90 ribosomal S6 kinase potentiates cisplatin activity in A549 human lung adenocarcinoma cells حسب Abdulrahman, Nabeel

"…Results: The combination of cisplatin and BI-D1870 potentiated the antimigration rate, the activation of caspases-3 and was associated with a significant decrease in RSK1 and ERK expression when compared to cisplatin alone. …"
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Mitigating Cardiotoxicity of Dendrimers: Angiotensin-(1-7) via Its Mas Receptor Ameliorates PAMAM-Induced Cardiac Dysfunction in the Isolated Mammalian Heart حسب Akhtar, Saghir

"…Methods: Hearts isolated from male Wistar rats underwent regional I/R and/or treatment with different PAMAM dendrimers, Ang-(1-7) or its MAS receptors antagonists. …"
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Correlating the rheological and magneto-optical properties of cobalt substituted magnetite ferrofluids (CoxFe1?xFe2O4) with theoretical studies حسب Babukutty, B.

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MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS حسب Hourani, Shireen Bayan

"…Finally, CSCs expressed a 100% higher ROS+ than TNBC. TNBC CSCs are quiescent, with highly functional DNA damage repair mechanism. …"
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Improving Concrete Durability by Using Optimized Aggregate Gradation and Reducing Cement Content حسب Chung, Hung-Wen

"…The potential performance of the pavement concrete mixes was also evaluated using critical stress analysis using a 3D FEM model. The compressive strength, modulus of rupture, modulus of elasticity, Poisson’s ratio, splitting tensile strength, coefficient of thermal expansion, rapid chloride permeability, and surface resistivity of the concrete mixes using normal Portland cement (Type I/II) and the concrete mixes using Type IL cement were similar to one another. …"
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Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation حسب El Hasasna, Hussain

"…RCE induced senescence and cell cycle arrest at G1 phase. These changes were concomitant with upregulation of p21, downregulation of cyclin D1, p27, PCNA, c-myc, phospho-RB and expression of senescence-associated β-galactosidase activity. …"
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The role of soluble uric acid in modulating autophagy flux and inflammasome activation during bacterial infection in macrophages حسب Al-Awad, Duha

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Supramaximal-Exercise Training Improves Heart Rate Variability in Association With Reduced Catecholamine in Obese Adults حسب Jabbour, Georges

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MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels. حسب Gomes da Silva, Isaura Isabelle Fonseca

"…Two molecular players act in the inflammation balance of the disease: MyD88 (Myeloid differentiation primary response 88) is related to TLR (Toll-like receptors) response and promotes the formation of myddosome complex resulting in increased inflammation; IRAK3 (Interleukin-1 receptor associated kinase 3) acts suppressing the myddosome complex thus decreasing inflammation. …"
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Performance assessment of inductive power transfer for railway applications حسب Almuhannadi, D.

"…The practical implementation has been conducted at a rated voltage of 100V DC at 50kHz and input power of 80W. …"
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Knowledge and Perception of and Attitude toward a Premarital Screening Program in Qatar: A Cross-Sectional Study حسب Al-Shafai, Mashael

"…Premarital screening (PMS) is a primary preventive measure to decrease the incidence of certain genetic disorders and sexually transmitted diseases. …"
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Short-term greenhouse emission lowering effect of biochars from solid organic municipal wastes حسب Rehrah D.

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The Cardiovascular Benefits of Empagliflozin, A Sodium Glucose Cotransporter Inhibitor: Is NHE1 a Viable Target? حسب Al-Shamasi, Al-Anood

"…In our study, we examine the cellular interplay between NHE1 and SGLT1/SGLT2 in a non-diabetic in vitro model. We characterized H9c2 cardiomyoblasts stimulated with Angiotensin II (ANG II) 100nM in the presence and absence of EMPA (500nM) and measured cardiomyocyte hypertrophy and the expression of NHE1 and SGLT1/2. …"
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Pilot-scale spiral wound membrane assessment for THM precursor rejection from upland waters حسب Golea, D.

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Pilot-scale spiral wound membrane assessment for THM precursor rejection from upland waters حسب Golea, D.

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Interfaces study of all-polysaccharide composite films حسب Šimkovic, I.

"…The lowest OT temperature was observed at QC/X = 1/3. We think it is due to the thermocatalytic effect of the 4-O-methyl-D-glucuronate in X and the QC quaternary groups on the thermolysis–thermo-oxidation mechanism. …"
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Zebrafish larvae as a model to demonstrate secondary iron overload. حسب Nasrallah, Gheyath K

"…The three assays showed that iron treatment alone resulted in a significant increase in total iron. Deferoxamine treatment of the iron-loaded zebrafish larvae showed a significant decrease in total iron concentration. …"
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Advanced Hard Ctings: Towards A Whole New World حسب Santecchia, Eleonora

"…The main problem with steel, is that it exhibits a relatively low hardness (below 10 GPa) which strongly decreases upon annealing above about 600 K. …"
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Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 حسب Letourneau, Ian D

"…BackgroundAppendicitis is a common surgical emergency that poses a large clinical and economic burden. …"
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