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d decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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step decrease » sizes decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
d decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Effect of partial Glo-I inhibition by EP on LPS-induced production of TNF-α, collagen-I and α-SMA in HSC.
Published 2017“…Co-treatment of LPS and EP indicated significant dose-dependent reduction of LPS-induced markers of inflammation <b>(A1)</b> and fibrosis <b>(B1, C1)</b>. Presence of LPS and treatment with low-level concentrations of MGO (indicating partial inhibition of Glo-I activity without complete enzyme inhibition) showed significant decrease of LPS-induced release of TNF-α (absence vs. presence of 10mM MGO: 371.8±22.7 vs. 60.9±11.2 pg/ml; p<0.001), collagen-I (10.0±0.3 vs. 1.8±0.5 ng/ml; p<0.001) and α-SMA (68.6±3.6 vs. 43.8±2.2 ng/ml; p<0.001) <b>(A2, B2, C2)</b>. …”
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Image_5_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif
Published 2022“…In this study, we generated TRAPS mutant mice and analyzed their phenotypes. Three Tnfrsf1a mutant strains were generated by introducing T79M, G87V, or T90I mutation. …”