High fat diet decreased tumor latency but did not affect survival in MMTV-PyMT transgenic mice. by Katherine V. Clark-Knowles (368164)

PLCε depletion leads to decreased basal Rap1 activity, which drives monolayer leak. by Peter V. DiStefano (3111639)

Alternative bounded and monotonically decreasing functions do not accurately fit the bias in the naïve SI. by Liron Sheintuch (12078310)

“…<p>(A-D) Fitting the naïve SI (blue) of simulated data using different types of bounded and monotonically decreasing functions with three free parameters. …”

Phlorizin decreased renal GTTR uptake, and increased serum drug levels <i>in vivo</i>. by Meiyan Jiang (438439)

CaMKIIδ deletion does not decrease VSMC proliferation or endothelial expression of VCAM-1 or CD54 (ICAM-1). by Jason A. Scott (443501)

Decreased response to IL-2 in CD4⁺CD25⁺ T cells is a phenotype common to T1D and MS, but not SLE subjects. by Karen Cerosaletti (501670)

Mean TOC concentration and mean bacterioplankton abundance for Santa Barbara Channel phytoplankton-DOC experiments. by Anna K. James (3812875)

Neurogenesis decreases over time in human prenatal retinal neurosphere cultures. by Lynda S. Wright (785238)

Age-stage-specific reproductive values (<i>v</i>_<i>xj</i>) of <i>A</i>. <i>glycines</i>. by Aonan Zhang (8933630)

Age-stage-specific reproductive values (<i>v</i>_<i>xj</i>) of <i>A</i>. <i>glycines</i>. by Aonan Zhang (8933630)

Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis by Raj Vuppalanchi (458660)

“…Six microRNAs (miR-155, miR-454, miR-582-5p, let-7f-1*, miR-181d, and miR-500) had >1.2-fold increase in cirrhotic livers and also had significant negative correlation with hepatic CYP3A activity (range of r = -0.44 to -0.52, P <0.05). …”

Knockdown of CoREST1 decreased tumor cell-mediated stimulation of endothelial cells <i>in vitro</i>. by Sohini Mazumdar (707540)

OSU-HDAC-44 decreased RhoA activity via srGAP1 induction, leading to F-actin dysregulation. by Yen-An Tang (187547)

“…(<b>D</b>) si-srGAP1 abrogated the OSU-HDAC-44-induced decrease in RhoA activity (<i>upper</i>) and rescued the normal structure of F-actin after OSU-HDAC-44 treatment (<i>lower</i>). …”

Rapamycin decreases neoblast proliferation and increases the survival rate in <i>Smed-smg-1</i> RNAi animals. by Cristina González-Estévez (175872)

Green tea polyphenols decrease cell viability and induces apoptosis in LNCaPshV and LNCaPshp53 cells. by Karishma Gupta (293144)

Decreased 11ß-HSD1 protein level by IGF-I overexpression <i>in vivo</i> and a direct treatment with IGF-I. by Subrata Chowdhury (787208)

“…N = 4, **P<0.01 vs. untreated. <b>D</b>. IGF-I treatment accelerated 11β-HSD1 protein degradation in 11β-HSD1 overexpressing MIN6 cells (as in Figs <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0136656#pone.0136656.g005" target="_blank">5</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0136656#pone.0136656.g006" target="_blank">6</a>). …”

Activation of mGluR5 site-specifically decreases spine density in the nucleus accumbens. by Kellie S. Gross (3115299)

SinV infection causes a decrease in Neuro 2a cells number and viability. by Leandro Silva da Costa (327641)

Loss of ZYG-8 decreases the rate of tubulin turnover at the spindle poles and spindle center. by Emily R. Czajkowski (14197638)

Modifying pregnenolone to decrease its lipophilicity results in decreased cellular uptake. by Jeffrey M. McManus (7512926)