Showing 1,841 - 1,860 results of 130,036 for search '(( i d decrease ) OR ( 5 ((step decrease) OR (((mean decrease) OR (a decrease)))) ))', query time: 1.78s Refine Results
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    Effect of partial Glo-I inhibition by EP on LPS-induced production of TNF-α, collagen-I and α-SMA in HSC. by Marcus Hollenbach (376231)

    Published 2017
    “…Co-treatment of LPS and EP indicated significant dose-dependent reduction of LPS-induced markers of inflammation <b>(A1)</b> and fibrosis <b>(B1, C1)</b>. Presence of LPS and treatment with low-level concentrations of MGO (indicating partial inhibition of Glo-I activity without complete enzyme inhibition) showed significant decrease of LPS-induced release of TNF-α (absence vs. presence of 10mM MGO: 371.8±22.7 vs. 60.9±11.2 pg/ml; p<0.001), collagen-I (10.0±0.3 vs. 1.8±0.5 ng/ml; p<0.001) and α-SMA (68.6±3.6 vs. 43.8±2.2 ng/ml; p<0.001) <b>(A2, B2, C2)</b>. …”
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    Image_5_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

    Published 2022
    “…In this study, we generated TRAPS mutant mice and analyzed their phenotypes. Three Tnfrsf1a mutant strains were generated by introducing T79M, G87V, or T90I mutation. …”