Inhibition of ADAM10 affects Notch targeted Hes5 and Gli genes in the ventral spinal cord (A–H) and in vitro cultured cell system (I–M). by Xin Yan (17064)

“…The ADAM10-mo transfected cells are green and the left side serves as a control. In situ hybridization using the antisense probes for Hes5 (B), Hes1 (C), Gli1 (F), Gli2 (G), and Gli3 (H) are labeled purple and cell nuclei are blue. …”

Drug-coated balloon versus conventional balloon angioplasty of hemodialysis arteriovenous fistula or graft: A systematic review and meta-analysis of randomized controlled trials -... by Min-Tsun Liao (4669771)

Visualization of choroidal thickness (CT) and en-face choriocapillaris (CC) images throughout different processing steps in 6x6mm scans of a healthy right eye. by Valentin Hacker (9956024)

Dendritic arborization and spine geometry of hippocampal CA1 pyramidal neurons are impaired in <i>Cdkl5</i> -/Y mice. by Kosuke Okuda (5150393)

“…There are no significant differences in the mean numbers of basal and apical dendrites between two genotypes (A,I). The number of nodes (B,F), endings (C,G), intersections (E), and length (D,H) of basal dendrites are significantly decreased in <i>Cdkl5</i> -/Y mice. …”

BCL2A1a Over-Expression in Murine Hematopoietic Stem and Progenitor Cells Decreases Apoptosis and Results in Hematopoietic Transformation by Jean-Yves Métais (127800)

The Role of <i>TLR4</i> 896 A><i>G</i> and 1196 C><i>T</i> in Susceptibility to Infections: A Review and Meta-Analysis of Genetic Association Studies by Panayiotis D. Ziakas (464048)

“…</p> <p>Conclusions</p><p>Depending on the type of infection and population, TLR4 polymorphisms are associated with increased, decreased or no difference in infectious disease. This may be due to differential functional expression of TLR4, the co-segregation of TLR4 variants or a favorable inflammatory response.…”

<i>Myh14</i> knock-down in stressed neonatal rat ventricular myocytes (NRVMs) causes abrogation of hypertrophic response and decreased cell viability. by Jessica Jen-Chu Wang (3158778)

“…<p>Knock-down of <i>Myh14</i> in NRVMs using siRNA (A), followed by ISO and phenylephrine (PHE) treatments, showed the <i>Myh14</i> knock-down treated NRVMs displayed poor attachment to tissue culture plates (B), did not undergo characteristic hypertrophy (C) and resulted in decreased cell viability based on MTT assay (D). …”

Remodelling of cytoplasmic vesicles during HSV-1 infection. by Kamal L. Nahas (13014698)

Subjects:

Structural en-face optical coherence tomography angiography images of an intermediate age-related macular degeneration eye, showing large choroidal vessels (LCV) within the chorioc... by Valentin Hacker (9956024)

Effect and interaction of SmsR1 on the potential target mRNA <i>pdhC</i> and acetylation level. by Jing Li (10611)

Mean scores and 95% CI of mental health symptoms, COVID-19 admissions and effect size during follow-up. by A. H. Ayesha Lavell (16734002)

Ursolic Acid Increases Skeletal Muscle and Brown Fat and Decreases Diet-Induced Obesity, Glucose Intolerance and Fatty Liver Disease by Steven D. Kunkel (156806)

Molecular signaling in response to diabetes. by Haroldo A. Toque (447341)

<i>Ubr5</i>^mt*/mt* limbs exhibit reduced <i>Ihh</i> expression. by Elaine Kinsella (2833466)

“…<p>(A-B) <i>Ihh</i> and (C,D) <i>Shh</i> qRT-PCR analysis of control <i>Prx1-Cre</i> (Con) or <i>Prx1-Cre; Ubr5</i>^{<i>mt*/mt*</i>} (<i>Ubr5</i>^<i>mt</i>) fore- or hind-limbs at (A,C) E13.5 or E15.5 (B,D) revealed significant decreases in <i>Ubr5</i>^<i>mt</i> limbs versus Con. qRT-PCR values were normalised against β-actin (n = 3, s.e.m indicated). …”

Decreased numbers of cells positive for Ki67 and BrdU in nodules of MB allograft treated with AAV-<i>Tis21</i> viral particles. by Dario Presutti (828288)

<i>Cebpd−/−</i> mice had increased apoptosis and mitotic index and decreased levels of γ-H2AX in intestinal crypts, post-TBI. by Snehalata A. Pawar (586961)

The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients. by Tao Zhang (43681)

“…Results show that, in normal crypts, the distribution and proportion of cells staining for ALDH1 and CGA are very similar. In contrast, in <i>APC</i>-mutant tissues from FAP patients, the proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases. …”

<i>c-REL</i> knockout leads to significantly decreased expression levels of NF-κB family member and cell cycle-associated genes. by Carsten Slotta (4326091)

“…<p><b>A:</b> qPCR analysis showing significantly decreased mRNA levels of NF-κB family members <i>RELA</i>, <i>NFKB1 (p50)</i>, <i>NFKB2</i> (<i>p52)</i>, <i>IKBKE</i> and <i>TBK1</i> in <i>c-REL</i> knockout cells compared to wildtype cells. …”

Model of the <i>D</i>. <i>discoideum</i> autophagic response during <i>M</i>. <i>marinum</i> infection. by Elena Cardenal-Muñoz (341021)

“…In addition, ESX-1 inhibits TORC1 activity early during infection (1.5 hpi), presumably through a nutrient-sensing pathway as described for other bacteria [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1006344#ppat.1006344.ref075" target="_blank">75</a>–<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1006344#ppat.1006344.ref077" target="_blank">77</a>]. …”

Characterization of Five ECF Sigma Factors in the Genome of <em>Pseudomonas syringae</em> pv. syringae B728a by Poulami Basu Thakur (389600)

“…Bioinformatic analysis of the B728a genome revealed 10 ECF sigma factors. This study analyzed deletion mutants of five previously uncharacterized ECF sigma factor genes in B728a, including three FecI-type ECF sigma factors (ECF5, ECF6, and ECF7) and two ECF sigma factors placed in groups ECF11 and ECF18. …”