Knockdown of HIF-1α decreases osteolytic lesions and improves survival of mice <i>in vivo</i>. by Lauren K. Dunn (260121)

Targeted point mutation (F639A) in the GluN1 subunit decreases ethanol sensitivity of NMDA receptors. by Carolina R. den Hartog (484817)

NO inhibition (L-NAME) <i>in viv</i>o results in increasing outward current in some PNs (A, B, C) and decreasing inward current in others (D, E, F). by Mark Higgins (312833)

“…<b>B</b>. Normalized current I–V plot for control, L-NAME (15 mM), and washout (mean +/− SE; n = 4). …”

Decreased trabecular bone mass in 6-month-old mice lacking <i>Ceacam1</i>. by Timo Heckt (671843)

Reduction of SIRT1 during DNA damage decreases the number of silent clones that have methylation. by Heather M. O'Hagan (271283)

“…(B) A dot plot of the mean number of CpGs methylated per HSVTK silenced clone from either un-siRNA treated cells (untreated) (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000155#pgen-1000155-g005" target="_blank">Figure 5D & E</a>), non-target siRNA treated cells (NT), or SIRT1 siRNA treated cells (SIRT1). …”

Proteins Significantly Decreased only in Metastatic UM Tumors. by John W. Crabb (158933)

“…<p>Average ratio (UM/control), standard error of mean (SEM), and p values (t-test) are shown for proteins significantly decreased only in metastatic tumors in LC MS/MS iTRAQ analyses of 5 metastatic and 5 non-metastatic primary UM tumors.…”

MCP-1-deficiency decreased CD11c-expressing cells via impairing the production of ROS and decreased activation of PLCγ2, Akt, and ERK upon M-CSF stimulation in BMM. by Woon-Ki Kim (447798)

“…<p>BMMs from WT (open bar) and MCP-1-KO mice (oblique-lined bar) were incubated in the presence of M-CSF (30 ng/ml) with U73122 (10 µM), Akt inhibitor IV (0.3 µM), PD098059 (5 µM), DPI (50 nM), NAC (3 mM), or H₂O₂ (300 µM) for 4 d (A). *, <i>P</i><0.05; ***, <i>P</i><0.001 compared with vehicle-treated WT cells. …”

LRRK2-KO neurites show increased motility and those from LRRK2-WT^OE and LRRK2-G2019S^OE show decreased motility on PLL. by Bryan Sepulveda (408810)

Effect of lysosomal hydrolysis inhibition on the decrease of PrP^Sc levels induced by CPZ or U18666A treatment. by Takeshi Yamasaki (521196)

VP16 protein abundance is decreased at low MOI in the ΔCTRL2 recombinant virus. by Pankaj Singh (116938)

Downregulation of DOM decreases the abundance of PER and TIM. by Zhenxing Liu (399809)

“…Downregulation of DOM decreased PER levels at CT1-5 and CT17-21. (Scale bar: 50 um.) …”

Decreased numbers of <i>dicer</i>^<i>CKO</i> P14 effector cells demonstrate an intrinsic role of Dicer during CD8 T cell expansion. by Florian M. Baumann (3119772)

IFN-γ deficiency decreases MCP-1 expression in Ang II-treated mouse hearts. by Ya-lei Han (167140)

Loss of virulence in the SIN kinase mutants is characterized by decreased fungal burden and host response to infection. by Ana Camila Oliveira Souza (8180958)

“…<b>E)</b> Inflammasome dependence of IL-1β release was established by co-culturing PMA-activated WT (THP1-null), <i>Nlrp3</i>^−/− (THP1-KO-NLRP3), and <i>Asc</i>^−/− (THP1-KO-ASC) THP-1 cells with CEA10 conidia (MOI 10:1) as indicated for (D). …”

<i>crh-1</i> mutants exhibit a decrease of <i>daf-7</i> expression in the ASI neurons. by JiSoo Park (11133976)

Colony survival is decreased in UUC-enriched deletion mutants after exposure to oxidative stress-inducing agents. by Lauren Endres (765718)

“…In the central figure, percent survival is shown relative to untreated wt. The inset shows the magnitude of the decrease in survival (i.e., percent survival untreated minus treated conditions for individual strains). …”

Long-term anti-nucleocapsid response by baseline patient characteristics. by Elizabeth S. Munroe (21568166)

Subjects:

Decreased CD4^pos iNKT cell numbers in the peripheral organs of T cell-specific <i>Gfi1</i>-deficient mice. by Toshiaki Yasuoka (2827457)

Decreased motor neuron survival in E18.5 GAD67-deficient (−/−) hypoglossal and phrenic motor nuclei. by Matthew J. Fogarty (283288)

VH14PEST decreases the toxicity of α-Syn as measured by a proteostatic assay with mhttex1-72QGFP. by David C. Butler (261919)