Showing 1,701 - 1,720 results of 129,996 for search '(( i d decrease ) OR ( 5 ((wt decrease) OR (((mean decrease) OR (a decrease)))) ))', query time: 2.04s Refine Results
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    Bortezomib in combination with the PLK1 inhibitor BI 2536 induces a significant downregulation of the total levels and phosphorylation of Bcr-Abl, a decrease of downstream phosphorylated STAT5 and a caspase-dependent cell death in TKIs-resistant and –sensitive K562 cell lines. by Octavian Bucur (470431)

    Published 2013
    “…K562 and K562-R cells were treated with 9nM bortezomib and 8nM BI 2536 for 60h, followed by the detection of Bcr-Abl and phosphorylated STAT5. The combined treatment resulted in a marked decrease of the total levels of Bcr-Abl, which correlates with a decrease in the phosphorylation of the downstream STAT5 protein, in both K562 and K562-R cells. β-Actin was used as an internal loading control. …”
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    Targeting <i>A20</i> decreases glioma stem cell survival. by Anita B. Hjelmeland (104655)

    Published 2010
    “…<p>(A) Annexin V staining demonstrates increased apoptosis with <i>A20</i> targeting in glioma stem cells isolated from a D317 glioma xenograft or a T3359 patient specimen passaged short term in immunocompromised mice. …”
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