R script and supporting information files for performing the ancestral state reconstruction analyses from <i>Pendraig milnerae</i>, a new small-sized coelophysoid theropod from the... by Stephan N. F. Spiekman (11519370)

Deletion of GIRK2, but not GIRK1, leads to increased Fos expression by the arcuate AgRP neurons. by Youjin Oh (3308670)

Table5_Dynamic Epicardial Contribution to Cardiac Interstitial c-Kit and Sca1 Cellular Fractions.DOCX by C. Pogontke (12677213)

“…</p><p>Results: Our data show that approximately 50% of cardiac c-Kit^POS cells are derived from the Wt1-lineage at E15.5. This subpopulation decreased along with embryonic development, disappearing from P7 onwards. …”

Dynamic changes of fetal head descent at term before the onset of labor correlate with labor outcome and can be improved by ultrasound visual feedback by Aly Youssef (5726285)

Dopaminergic neuron differentiation is disrupted in <i>Dkk1</i> mutants. by Diogo Ribeiro (230483)

“…Quantification in (B) revealed a 40% decrease in the numbers of dopaminergic neurons in <i>Dkk1^+/−</i> embryos when compared to <i>Wt</i> littermate controls (mean ± s.e.m- <b><i>Wt</i></b><b>:</b> 568.3±31.7, N = 3; <b><i>Dkk1^<b>+/−</b></i></b><b>:</b> 346.5±27.2, N = 8 p = 0.0015 ** unpaired t-test). …”

Table_5_Transcriptome characteristics during cell wall formation of endosperm cellularization and embryo differentiation in Arabidopsis.xls by Chengcheng Li (2591632)

“…Here, we characterized the early embryo and endosperm development of the naa15 mutant that had abnormal embryo differentiation and incomplete endosperm cellularization compared to WT of Arabidopsis, and comparatively investigated the changes of gene expressions in WT seeds at 3, 4, and 5 days after pollination (3W, 4W, and 5W) and the white homozygous aborted naa15 seeds at 5, 6, and 7 DAP (5M, 6M, and 7M) from naa15-1/+ siliques using RNA sequencing and qPCR assays. …”

Image_5_Transcriptome characteristics during cell wall formation of endosperm cellularization and embryo differentiation in Arabidopsis.jpeg by Chengcheng Li (2591632)

“…Here, we characterized the early embryo and endosperm development of the naa15 mutant that had abnormal embryo differentiation and incomplete endosperm cellularization compared to WT of Arabidopsis, and comparatively investigated the changes of gene expressions in WT seeds at 3, 4, and 5 days after pollination (3W, 4W, and 5W) and the white homozygous aborted naa15 seeds at 5, 6, and 7 DAP (5M, 6M, and 7M) from naa15-1/+ siliques using RNA sequencing and qPCR assays. …”

Image 1_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…We detected both Zinc finger E-box-binding homeobox 1 (ZEB1) gene and zinc finger protein 469 (ZNF469) gene pathogenic variant in the proband and another two patients in this family, including a heterozygous missense variation c.13C>G (p.P5A, rs753301298) in the ZEB1 gene, and a heterozygous non-frameshift variant c. 3093_3104del (p.D1035_K1038del) in the ZNF469 gene. …”

Image 3_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…We detected both Zinc finger E-box-binding homeobox 1 (ZEB1) gene and zinc finger protein 469 (ZNF469) gene pathogenic variant in the proband and another two patients in this family, including a heterozygous missense variation c.13C>G (p.P5A, rs753301298) in the ZEB1 gene, and a heterozygous non-frameshift variant c. 3093_3104del (p.D1035_K1038del) in the ZNF469 gene. …”

Image 2_Polymorphous corneal dystrophy subtype 3 and keratoconus aggravation after corneal refractive surgery in a three-generation family carrying both ZEB1 and ZNF469 pathogenic... by Qinghong Lin (14162640)

“…We detected both Zinc finger E-box-binding homeobox 1 (ZEB1) gene and zinc finger protein 469 (ZNF469) gene pathogenic variant in the proband and another two patients in this family, including a heterozygous missense variation c.13C>G (p.P5A, rs753301298) in the ZEB1 gene, and a heterozygous non-frameshift variant c. 3093_3104del (p.D1035_K1038del) in the ZNF469 gene. …”

<b>Dataset to the article: The toxicological assessment of a novel spiro derivative, 4-amino-1-azaspiro[4.5]dec-3-en-2-one for the Greater wax moth, </b><b><i>Galleria mellonella</... by Jamin Ali (18297142)

“…Additionally, a significant decrease in protein content and an increase in phenol-oxidase activity were observed with alterations in α and β-esterase activities. …”

Data_Sheet_1_Plant-based default nudges effectively increase the sustainability of catered meals on college campuses: Three randomized controlled trials.docx by Renate D. Boronowsky (14079303)

“…</p>Conclusion<p>Results demonstrated plant-based default menu options are effective, providing a low-effort, high-impact way to decrease consumption of animal products in catered events. …”

Characteristics of the core genetic components of <i>S</i>. <i>meliloti</i>. by George C. diCenzo (650171)

“…Legend abbreviations: AA–amino acid; Attach–attachment; Carb–carbohydrate; Cofact–cofactor; e-–electron; Met–metabolism; Misc–miscellaneous; Mot–motility; Nucl–nucleotide; Oxidoreduct–oxidoreductase activity; Prot–protein; Trans–transduction. (<b>D</b>-<b>F</b>) Scatter plots comparing the fitness phenotypes, shown as the log₁₀ of the GEI scores (Gene Essentiality Index scores; i.e., number of insertions within the gene divided by gene length in nucleotides) of (<b>D</b>) wild-type grown in rich medium versus wild-type grown in defined medium, (<b>E</b>) wild-type grown in rich medium versus ΔpSymAB grown in rich medium, and (<b>F</b>) wild-type grown in defined medium versus ΔpSymAB grown in defined medium.…”

The <i>topbp1</i> gene is disrupted in mutant^{<i>cas003</i>}. by Lei Gao (6566)

“…The <i>topbp1</i> MO, as validated in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005346#pgen.1005346.s003" target="_blank">S3 Fig</a>, was injected into one-cell stage wild-type embryos to produce <i>topbp1</i> morphants. …”

Expression analysis of <i>FGFR1–4</i> and <i>Sema3A</i>. by Rosa-Eva Huettl (113537)

“…(<b>K</b>’, <b>L</b>’) Immunohistochemistry against Isl-1/2 to illustrate sensory neurons in the DRG. (<b>M</b>) Quantification of expression levels reveals a significant decrease of <i>FGFR2 in situ</i> hybridization signal in the LMC of <i>FGFR2^flox/flox;Olig2-Cre⁺</i> mutant embryos, while expression levels of <i>FGFR1, FGFR3</i> and <i>FGFR4</i> in the LMC remain unchanged (p<i>^FGFR1</i> = 0,52; p<i>^FGFR3</i> = 0,45, p<i>^FGFR4</i> = 0,78). …”

Eicosapentaenoic acid prevents arterial calcification in <i>klotho</i> mutant mice by Kazufumi Nakamura (336712)

“…</p><p>Methods and results</p><p>Four-week-old <i>klotho</i> mutant mice and wild-type (WT) mice were given a diet containing 5% EPA (EPA food, <i>klotho</i> and WT: n = 12, each) or not containing EPA (control food, <i>klotho</i> and WT: n = 12, each) for 4 weeks. …”

Schematic representation showing different phases and outcomes of stochastic bubbles for (4) with <i>b</i> = 0.42, <i>g</i> = −0.04, <i>σ</i>_<i>x</i> = 0.6, <i>σ</i><sub... by Damian Smug (5040890)

“…<b>(A)</b> and <b>(B)</b> Foreshocks {1/2} and {3/4} preceding the main crash {5/6} are clearly visible. …”

Excessive Osteocytic Fgf23 Secretion Contributes to Pyrophosphate Accumulation and Mineralization Defect in Hyp Mice by Sathish K. Murali (2585914)

“…<div><p>X-linked hypophosphatemia (XLH) is the most frequent form of inherited rickets in humans caused by mutations in the phosphate-regulating gene with homologies to endopeptidases on the X-chromosome (<i>PHEX</i>). <i>Hyp</i> mice, a murine homologue of XLH, are characterized by hypophosphatemia, inappropriately low serum vitamin D levels, increased serum fibroblast growth factor-23 (Fgf23), and osteomalacia. …”

Fatty acids composition (mol%) of total lipids from placenta (tissue), and placental mitochondria, from control and hyperglycemic rats at 19 days of pregnancy. by María del Consuelo Figueroa-García (832711)

<i>cul3</i> and <i>kel</i> interact genetically, mutations in <i>kel</i> rescue the <i>cul3</i>-mutant phenotype. by Inna Djagaeva (369627)

“…Note: small protrusions were not counted in <i>cul3</i>-mutant ddaE and ddaD neurons. Decreasing levels of Kelch in <i>cul3^gft2 kel^DE1</i> double-mutant single-cell clones partially or completely rescued the <i>cul3</i>-mutant phenotype. ***: p<0.001, **: p<0.01.…”