HVR1-swap compensatory E1/E2 substitutions typically decrease virus entry dependency on SR-BI. by Christina Holmboe Olesen (11154333)

Knock-down of Atox1 in SW620 cells decreased cell migration and colony formation. by Arundhati Jana (157555)

Decreased CD39 protein expression by islet resident macrophages heralds T1D in NOD mice. by Thomas B. Thornley (2550766)

Netrin-1 overexpression increases HCV RNA and specific infectivity of HCV virions in vitro whereas Netrin-1 depletion decreases HCV RNA and specific infectivity in vitro. by Marie-Laure Plissonnier (337713)

“…<b>H</b>. Netrin-1 depletion impedes HCV. Huh7.5 cells were transfected with siRNAs, infected at a MOI of 0.1 24 h after seeding, and trypsinized at day five post-infection before a second siRNA transfection. …”

Loss of ALS2 results in decreased levels of the lysosome-dependent degradation of LC3 in fibroblasts. by Shinji Hadano (251529)

“…It is notable that a 6 hr of starvation leads to decreased levels of the LC3- and p62-immunoreactive signals in WT cells, but not in <i>Als2</i>^−/− cells. …”

Overexpression of FTH1P3 decreased the miR-224-5p expression. by Xiaoli Zheng (232806)

“…<p>(A) Elevated expression of FTH1P3 decreased the miR-224-5p expression in the MUM-2B cell. …”

LRP deficiency in MΦ's results in normal IFN-γ response but decreased IL-4. by Roman Covarrubias (602292)

Constitutive KIT activation in cells with gain-of function KIT mutations causes increased ROS levels and decreased DJ-1. by Do-Kyun Kim (2176492)

NEDD4 knockout decreases IFITM3 ubiquitination and protects cells from virus infection. by Nicholas M. Chesarino (781971)

GCase substrate levels are altered in the brain and liver of homozygous <i>GBA1</i> D409V KI mice. by Nicole K. Polinski (10947787)

Subjects:

Blocking VIP-signaling decreased inflammation and necrosis in the liver and lung of mCMV-infected mice. by Jian-Ming Li (319425)

Dopamine turnover, but not total dopamine levels or nigral dopamine neuron numbers, are altered in aged homozygous <i>GBA1</i> D409V KI mice as compared to controls. by Nicole K. Polinski (10947787)

Subjects:

Microgliosis and astrogliosis are not exacerbated by homozygous GBA1 D409V mutation in the striatum and substantia nigra. by Nicole K. Polinski (10947787)

Subjects:

Silencing <i>cullin-1/5</i> decreased mRNA and protein expression of NF-κB dependent cytokines. by Attinder Chadha (11414273)

Subjects:

Silencing of <i>Aacasps16</i> led to decreased apoptosis induced by UV and Act D treatment. by Kun Meng (141278)

Osteocyte-rich cell fractions isolated from <i>Hyp</i> femurs show increased mRNA expression of PPi-regulating genes and decreased mRNA expression of <i>Tnap</i> ex vivo. by Sathish K. Murali (2585914)

Total and phosphorylated alpha-synuclein levels are unchanged in the homozygous <i>GBA1</i> D409V KI mouse brain at 12 months of age. by Nicole K. Polinski (10947787)

Subjects:

Decreased co-localization of Py with the late endosome and lysosome in GD1a-supplemented cells. by Mengding Qian (263231)

GluN2A(D731N) reduces the agonist potency. by Kai Gao (120150)

“…<p>(<b>A,B</b>) Representative TEVC recordings obtained from oocytes expressing WT GluN1/GluN2A (WT 2A) receptors (<b>A</b>) and GluN1/GluN2A(D731N) (2A-D731N) receptors (<b>B</b>) in which the currents were evoked by increasing concentrations (μM) of glutamate (in the presence of 100 μM glycine) at the holding potential of -40 mV. …”

Heterozygous TIN2-R282H mutation decreases the frequency of telomere extension by telomerase. by Amanda K. Frank (778017)