Image_4_Switch of NAD Salvage to de novo Biosynthesis Sustains SIRT1-RelB-Dependent Inflammatory Tolerance.TIF by Jingpu Zhang (1430263)

“…In contrast, high dose endotoxin drove a shift of NAD synthesis pathway from early NAMPT-dependent NAD salvage to late indoleamine 2,3-dioxygenase-1 (IDO1)-dependent NAD de novo biosynthesis, leading to persistent immune suppression. …”

An example of the procedure of the experiment. by Motonori Kurosumi (11237990)

JH regulates ovarian development: (A) The application of <i>HMGR</i>-<i>JHAMT</i> dsRNA results in a dramatic decrease of JH biosynthesis (n = 16). by Juan Huang (41654)

Experiment of rotating the Collison nebulizer (a) schematic of the Collison nebulizer rotation changing the path length; (b) results of the laser intensity change. by Elliott Donghyun Kim (19469973)

GdA’s effect on morphological variation differs in yeast strains possessing spontaneous mutations or recombinations, as compared to natural yeast isolates. by Kerry A. Geiler-Samerotte (462866)

“…<p>In (A–C), each point is plotted to represent between-strain morphological variation (standard deviation) in the GdA+ condition minus that in the GdA− condition; colored dots represent significant variance increases (green) or decreases (purple) in GdA+ versus GdA− (significance defined as when the 95% credible interval surrounding the difference does not overlap zero). …”

D-4F normalizes insulin levels. by Kristine C. McGrath (8269155)

SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress by Mengli Zhang (6331172)

“…As a result, SIRT5 deficiency decreases mitochondrial ATP production, increases AMP/ATP ratio, and subsequently activates AMP-activated protein kinase (AMPK) in cultured cells and mouse hearts under energy stress conditions. …”

MiR-145-5p inhibition rescues ROCK1 expression following OIP5-AS1 silencing in I/R Injury. by Jingyan Yang (7120994)

SIRT5 KO leads to increased AMP/ATP ratio and AMPK activation in HEK293T cells. by Mengli Zhang (6331172)

NOD2-mediated Suppression of CD55 on Neutrophils Enhances C5a Generation During Polymicrobial Sepsis by Sae Jin Oh (135988)

“…Injection of recombinant C5a decreased survival rates of Nod2^−/− mice rate during sepsis, whereas it did not alter those in wild type mice. …”

Sirt5 KO leads to increased AMP/ATP ratio and AMPK activation in mouse hearts. by Mengli Zhang (6331172)

Characterization of optogenetically-evoked DA dynamics as a square wave dip. by Hidetoshi Urakubo (578508)

Loss of <i>CDK8</i> decreased the elevated RNAPII-CTD S₅ phosphorylation levels at Ty1 retrotransposons observed in the <i>rpb1-CTD11</i> mutant. by Maria J. Aristizabal (451648)

Immunofluorescent staining with vWF. by Jae Heon Kim (10454261)

“…<p>Immunofluorescent staining with vWF showed a decrease in the number of vWF-positive cells in the group with BOO and an increase in vWF-positive cells after transplantation of hMSCs. …”

Baseline identification of clonal V(D)J sequences for DNA-based minimal residual disease detection in multiple myeloma by Even H. Rustad (6499169)

“…As a molecular control for tumor cell content, we sequenced the samples using our in-house myeloma panel myTYPE. …”

Cytokine (IL-4 and IL-13) concentrations in BAL fluid of mice fed (n-3) or (n-6) PUFA enriched foods for 8 weeks and then sensitized and challenged with OVA for an additional 4 wee... by Jean A. Hall (289030)

Percent of lung tissue staining positive with periodic acid-Schiff (PAS) stain for mucus and rat anti-mouse CD45 stain, after mice were fed (n-3) or (n-6) PUFA enriched foods for 8... by Jean A. Hall (289030)

Average nutrient composition (dry matter basis) of diets fed to mice for 12 weeks. by Jean A. Hall (289030)

BAL fluid cytology proportions for mice fed (n-3) or (n-6) PUFA enriched foods for 8 weeks and then sensitized and challenged with OVA for an additional 4 weeks compared with mice... by Jean A. Hall (289030)

Representative light microscopy images of lung tissue. by Jean A. Hall (289030)