Relative abundance. by Tejaswini Baral (14320736)

Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Heatmap of topmost bacteria genera. by Tejaswini Baral (14320736)

Face angle used as stimuli. by Motonori Kurosumi (11237990)

PTX- and Bz-based therapies improve the disbalance of neurotransmitters and BDNF in <i>Trypanosoma cruzi</i>-infected mice. C57BL/6 mice were infected with 100 bt of the Colombian... by Glaucia Vilar-Pereira (686134)

Influence of chemical components of PVAC during storage of RBC. by Felix Sellberg (8098511)

“…In <b>(b)</b> values after 1 month (end of storage) are shown: PVA at 100 μg/mL increased hemolysis while PVAC at 2.5 mg/mL, 500 and, 100 μg/mL decreased the levels of hemolysis compared to the control.…”

The frequency (<i>FD</i>) and the level (<i>LD_av</i>) of the <i>CHL1</i> mRNA decrease in renal cancer (CC-RCC). by Vera N. Senchenko (53211)

DataSheet_5_Long-Term Effects of Allogeneic Hematopoietic Stem Cell Transplantation on Systemic Inflammation in Sickle Cell Disease Patients.xlsx by Júlia Teixeira Cottas de Azevedo (11816621)

“…Overall survival was 94% with no severe (grade III-IV) graft-vs-host disease and a 22% rejection rate (graft failure). Hematological parameters, reticulocyte counts, and levels of lactate dehydrogenase (LDH), endothelin-1 and VCAM-1 normalized in SCD patients post-HSCT. …”

Hepatic IRE1α/XBP1 pathway of the UPR is decreased in pediatric cholestatic liver disease (pCLD) samples compared to pediatric normal (pNormal) livers. by Alyssa Kriegermeier (4707226)

“…<p>A) Hepatic gene expression of IRE1α, XBP1s and downstream targets EDEM1 and ERdj4 were measured via qPCR. pCLD livers (n = 10) had decreases in IRE1α, XBP1, EDEM1 and ERdj4 expression compared to pNormal livers (n = 9). …”

Histamine 1 Receptor Blockade Enhances Eosinophil-Mediated Clearance of Adult Filarial Worms by Ellen Mueller Fox (774436)

“…Although fexofenadine-treated mice had decreased antigen-specific IgE levels as well as lower splenocyte IL-5 and IFNγ production, they exhibited a greater than fourfold rise in eosinophil numbers at the tissue site where adult <i>L</i>. …”

Immune modulation by histamine during <i>L</i>. <i>sigmondontis</i> infection. by Ellen Mueller Fox (774436)

Image_1_Loss of the Essential Autophagy Regulators FIP200 or Atg5 Leads to Distinct Effects on Focal Adhesion Composition and Organization.TIF by Emelia A. Assar (9201743)

“…We provide evidence suggesting the primary autophagy regulators Atg5 and FIP200 both play a role in cell motility and extracellular matrix adhesion. …”

Image_2_Loss of the Essential Autophagy Regulators FIP200 or Atg5 Leads to Distinct Effects on Focal Adhesion Composition and Organization.TIF by Emelia A. Assar (9201743)

“…We provide evidence suggesting the primary autophagy regulators Atg5 and FIP200 both play a role in cell motility and extracellular matrix adhesion. …”

Programmed Release METTL3-14 Inhibitor Microneedle Protects Myocardial Function by Reducing Drp1 m6A Modification-Mediated Mitochondrial Fission by Boyue Huang (17051857)

“…RIP assay and mechanistic investigation confirmed that METTL3 inhibition reduced the translation efficiency of Drp1 mRNA by 5′UTR m6A modification, thus decreasing the Drp1 protein level and mitochondrial fragment after hypoxic-ischemic injury. …”

Table_2_Systemic Immune Dysregulation in Early Breast Cancer Is Associated With Decreased Plasma Levels of Both Soluble Co-Inhibitory and Co-Stimulatory Immune Checkpoint Molecules... by Bernardo L. Rapoport (7431842)

Table_1_Systemic Immune Dysregulation in Early Breast Cancer Is Associated With Decreased Plasma Levels of Both Soluble Co-Inhibitory and Co-Stimulatory Immune Checkpoint Molecules... by Bernardo L. Rapoport (7431842)

Mutations in CREB and NF-kB response elements decrease EP3 RNA production without altering cell morphology and gene expression, opposite to GC-box mutations. by Qiaolin Hu (8677473)

Table3_Inflammatory-Metal Profile as a Hallmark for COVID-19 Severity During Pregnancy.docx by Johana Vásquez-Procopio (13217553)

“…Robust negative correlations between iron/magnesium and zinc/IL-6, and a positive correlation between copper/IP-10 were observed in pregnant women with the severe form of the disease. …”

Table2_Inflammatory-Metal Profile as a Hallmark for COVID-19 Severity During Pregnancy.docx by Johana Vásquez-Procopio (13217553)

“…Robust negative correlations between iron/magnesium and zinc/IL-6, and a positive correlation between copper/IP-10 were observed in pregnant women with the severe form of the disease. …”

Table1_Inflammatory-Metal Profile as a Hallmark for COVID-19 Severity During Pregnancy.xlsx by Johana Vásquez-Procopio (13217553)

“…Robust negative correlations between iron/magnesium and zinc/IL-6, and a positive correlation between copper/IP-10 were observed in pregnant women with the severe form of the disease. …”