Search alternatives:
point decrease » point increase (Expand Search)
de decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
i de » i e (Expand Search), i d (Expand Search), _ de (Expand Search)
point decrease » point increase (Expand Search)
de decrease » we decrease (Expand Search), _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
i de » i e (Expand Search), i d (Expand Search), _ de (Expand Search)
-
15061
-
15062
-
15063
Representative activity cliffs for the proprietary hERG blocker series 1 (see text) comprised of R1 (corresponding to BP) and R2/R3 (corresponding to BC).
Published 2020“…<p>The large decrease in percent inhibition @ 1 μM for structure 3 compared with structures 1 and 2 is putatively attributable to the greater re-solvation cost of Cl versus F, together with increased polarity and solubility/de-solvation cost of the ortho- versus meta-pyridyl nitrogen, (consistent with the lack of hERG-contributed H-bond replacements for the water solvating this moiety in the unbound state).…”
-
15064
-
15065
-
15066
-
15067
-
15068
-
15069
-
15070
-
15071
<i>NHD13/Rag1</i>KO mice have decreased survival and an increased incidence of leukemia.
Published 2013“…<p>(A) Survival is dramatically reduced in the <i>NHD13</i> mice and further decreased in the <i>NHD13/Rag1</i>KO cohort (Mantel Cox test p = 0.01); median lifespan of the <i>NHD13/Rag1</i>KO mice is two months less than the NHD13 cohort. …”
-
15072
-
15073
-
15074
Selected PK parameters and clinical signs in ferrets challenged with influenza A viruses (Study 1).
Published 2015“…The number of ferrets per total number of animals in that group that had more than a 5% loss of initial weight on day 5 p.i. is shown in parenthesis.…”
-
15075
-
15076
-
15077
-
15078
-
15079
-
15080