Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

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Genetic information on 5 subjects carrying <i>NR5A1</i> mutations. by Jana Malikova (615672)

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Folding and stability of GDAP1 as affected by CMT mutations. by Aleksi Sutinen (10039145)

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Increasing glucose (D-Glu) concentrations decreases TNF-mediated A20 protein up-regulation without affecting its transcriptional activation in SMC. by Gautam V. Shrikhande (227350)

Increasing glucose (D-Glu) concentrations decreases TNF-mediated A20 protein up-regulation without affecting its transcriptional activation in EC. by Gautam V. Shrikhande (227350)

Plasma from ATTR individuals presents a higher proteolytic activity. by Gonçalo da Costa (198731)

Number of significantly significant (P < 0.05) differentially abundant (SSDA) proteins showing increased or decreased activity (fold change +/- 1.5-fold) relative to time 0 following storage at 9°C or 20°C of infective juveniles of <i>S</i>.... by Peter E. Lillis (12368582)

“…<p>Number of significantly significant (P < 0.05) differentially abundant (SSDA) proteins showing increased or decreased activity (fold change +/- 1.5-fold) relative to time 0 following storage at 9°C or 20°C of infective juveniles of <i>S</i>. …”

Knockout of <i>PDLIM2</i> results in increased STAT2 upon interferon treatment, decreased association with ubiquitin and increased nuclear retention. by Michael A. Joyce (267535)

Gut richness and diversity decrease significantly by week 5 of chemoradiotherapy. by Molly B. El Alam (10231830)

CyaA decreases the capacity of TLR-stimulated DCs to present soluble antigen to CD4⁺ T cells. by Irena Adkins (173166)

Proinflammatory signaling pathways were decreased in Ad26.COV2.S vaccinated compared to sham unvaccinated hamsters. by Malika Aid (7303874)

“…<p><b>(A)</b> Boxplots of SARS-CoV-2 transcripts normalized read counts across all animals, vaccinated hamsters are shown in blue and pink, and sham animals in green. …”

Reduction of OTUB1 decreased NS2-mediated vRNP nuclear export. by Yu-Jyun Li (18700176)

Osteogenic differentiation of mesenchymal stem cells is enhanced in a 45S5-supplemented β-TCP composite scaffold: an <i>in-vitro</i> comparison of Vitoss and Vitoss BA - Fig 3 by Fabian Westhauser (5314436)

“…<p><b>3D-mCT reconstruction and 2D-mCT slice of one representative Vitoss (a, b) and Vitoss BA scaffold (c, d). …”

siRNA-mediated depletion of CUL5 in HUVEC prevents thalidomide-dependent decrease in cellular proliferation. by Bryan Kunkler (5204327)

Decrease of excitability in small IB4-positive TG neurons over-expressing TRESK channels. by Zhaohua Guo (383295)

Selective downregulation of SR Ca²⁺ handling proteins and decreased SR Ca²⁺ uptake in TG mice hearts. by Mayilvahanan Shanmugam (691549)

“…<b>*</b>indicates the significant difference (p<0.05) between NTG and TG groups. n = 5. Calcium dependent SR Ca²⁺ uptake is significantly decreased in atria <b>(E)</b> and in the ventricles <b>(F)</b> of one-month old TG mice. …”

Homologues of the <i>A</i>. <i>thaliana</i> gene AT3G59280 identified by BlastP search (E value < 1E-5). by Chloe Casey (14341756)

Mammalian METTL10 is an EF1A1 KMT. by Tadahiro Shimazu (619411)

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Gene ontology biological processes overrepresented among genes exhibiting decreased expression in human psoriasis. by William R. Swindell (175427)

“…<p>A total of 3540 transcripts were identified as significantly decreased in psoriatic plaques obtained from human patients relative to normal skin obtained from control subjects (FDR-adjusted P<0.05 and log₂-transformed fold-change less than -0.50). …”

Decreased ovary size and defective oogenesis following specific targeting of <i>Hdac2</i> and reduction of <i>Hdac1</i> in oocytes. by Pengpeng Ma (389371)