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point decrease » point increase (Expand Search)
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e decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Data_Sheet_1_UGT1A1 Variants c.864+5G>T and c.996+2_996+5del of a Crigler-Najjar Patient Induce Aberrant Splicing in Minigene Assays.PDF
Published 2020“…Thus, the three anomalous transcripts are likely to inactivate UGT1A1. Moreover, this patient is also homozygous for the promoter variant A(TA)7TAA that decreases UGT1A1 expression by 70%, so the full-length transcript produced by c.864+5G>T would be even more reduced (<9%), thus supporting the diagnosis of CNS-type II. …”
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Patients with HIV have less E-cadherin in their lung epithelium.
Published 2016“…<p><b>A.</b> There is a slight decrease in steady state E-cadherin mRNA as detected by RT-qPCR. …”
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HDR brachytherapy decreases proliferation rate and cellular progression of a radioresistant human squamous cell carcinoma in vitro
Published 2017“…</p> <p><b>Conclusion:</b> HDR brachytherapy led to a decreased proliferation rate and cell survival and also hampered cellular progression to mitosis suggesting that tumor cell death mainly occurred due to mitotic death and G<sub>2</sub>/M cell cycle arrest.…”
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Potent 5‑Cyano-6-phenyl-pyrimidin-Based Derivatives Targeting DCN1–UBE2M Interaction
Published 2019“…Defective in cullin neddylation 1 (DCN1), as a co-E3 ligase, interacts with UBE2M to enhance the activation of CRLs, and this interaction is emerging as a therapeutic target for human diseases. …”
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