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1341
TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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1342
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1343
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1344
Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver.
Published 2021“…(A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”
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1345
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1346
Decrease of ECT2 phosphorylation at T359 residue in DLC1 overexpressing cells.
Published 2018“…<p><b>A.</b> Significant decrease in two phosphopeptides (ANTPELK) and (ANTPELKK, with one missed cleavage) in DLC1-FL overexpressing cells compared to control vector cells (FDR-corrected <i>p</i>-value < 0.1). …”
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1347
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1348
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1349
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1350
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1351
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1352
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1353
The CLP Population is Significantly Decreased in Arid3b null mice.
Published 2016“…<b>D)</b> HSC populations were unchanged between control and <i>Arid3b</i><sup><i>-/-</i></sup> mice. <b>E)</b> 3 weeks after final pIpC injection, bone marrow was harvested from <i>Arid3b</i><sup><i>fl/fl</i></sup>: <i>Mx1-Cre</i> mice and lineage depleted to enrich for hematopoietic stem and progenitor cells. …”
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1354
GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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1355
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1356
Decrease of C/EBPβ protein expression attenuates DEX-induced repression of CBG mRNA and protein levels and reduces GR recruitment to the mouse <i>Cbg</i> promoter.
Published 2014“…(E) To examine the effect of decreased C/EBPβ protein expression on GR recruitment to the mouse <i>Cbg</i> promoter, BWTG3 cells were transfected with siRNA as described above. …”
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1357
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1358
All Ca<sub>V</sub>3.3 variants left-shift the voltage dependence of inactivation.
Published 2025Subjects: -
1359
Interaction energies of the Ca<sub>V</sub>3.3 A398 amino acid substitutions.
Published 2025Subjects: -
1360