Activated CD4+ CD45RO+ memory T-cells decrease secretion of soluble caspase-1 and P2X7R mRNA expression in monocytes leading to a reduced response upon ATP binding. by Vanessa Beynon (153924)

“…A significant decrease of soluble Caspase-1 in the supernatant of cells co-cultured with activated memory T-cells was observed both in the presence and absence of IFNβ; b) intracellular levels of pro-IL-1β measured with an ELISA specific for the immature precursor of IL-1β showed a significant increase in pro-IL-1β levels in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3), cell lysates from adherent monocytes were obtained after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP c) the ratio of intracellular pro-IL-1β to released soluble Caspase-1 is significantly increased in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3). d) <i>P2X7R</i> mRNA expression in monocytes cultured overnight with activated CD4+CD45RO+ memory T-cells is decreased with and without addition of exogenous IFNβ (n = 3), mRNA was isolated from adherent monocytes after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP (Data are shown as means ± SD of duplicate cultures; *p<0.05; **p<0.01 employing repeated measures ANOVA with post-hoc Bonferroni adjustment for multiple comparisons to avoid random correlations); e) Ca²⁺-influx measurement in monocytes cultured with activated human CD4+CD45RO+ memory T-cells in the presence of IFNβ demonstrates the absence of slow sustained Ca²⁺-influx mediated by ATP binding to the purinergic P2X7-receptor (representative of 3 independent experiments); f) Annexin V staining of monocytes coincubated with T-cells and stimulated with LPS was measured by flow cytometry (representative flow cytometry histogram of n = 5).…”

p63^TECko mice have decreased TECs and DN1 cells in embryonic mice. by Heather E. Stefanski (5058746)

Depletion of neutrophils is associated with a decreased number of CD4 T cells, B cells, eosinophils, DCs and MDSc during the chronic stages of <i>P</i>. <i>brasiliensis</i> infecti... by Juan David Puerta-Arias (3187089)

Prevalence of antimicrobial resistance to gentamicin and streptomycin antimicrobials exhibits a decreasing linear trend from 2002–2016. by Kelly E. Davidson (5464472)

Respective increase and decrease in Myc and NRF1/TFAM in kidneys from rats administered Tl. by Sho Sugahara (11895828)

Skeletal abnormalities in <i>Slc35a3</i>^{<i>–/–</i>}mice. by Soichiro Saito (15285875)

Elimination of GLUT1 expression in G1fPt cells decreases tumor growth. by Christian D. Young (211228)

YY1 associates with the arginine methyl transferase PRMT5 to regulate ITCH repression during Mtb infection. by Salik Miskat Borbora (9381455)

Subjects:

Over-expression of miR-199b-5p decreases the CD133+ compartment of Daoy cells. by Livia Garzia (266719)

“…<p>A–F) Representative FACS analyses of the stable 199bSC1 (D) and 199bMC1 (F) clones showed a decrease in the percentage of cells that were positive for the stem cell marker CD133 (B); A, C and E are negative controls (no antibody).…”

Antitumor Activity of FGFR Inhibitor as a Result of a Decrease in the Breast TIC Subpopulation In Vivo. by Sungeun Kim (105743)

TH588 effectively decreases cellular survival in heterogeneous neuroendocrine tumor cells. by Elke Tatjana Aristizabal Prada (833927)

Sensitivity of the PCR for decreasing concentrations of genomic DNA purified from <i>Veillonella</i> species using species-specific primer sets. by Izumi Mashima (3165120)

(A) The proportion of fast MyHC myotubes is decreased in Igf-2 deficient mice (maternal disomy Chromosome 7 - MatDi) at E14 by Deborah Merrick (54928)

“…(B) Embryo immunoblotting for Igf-2 demonstrates a stage related increase in Igf-2 protein between E10.5 and E15.5 in WT and absence of Igf-2 in MatDi embryos at E14.5 and E15.5 Tracks 1–4 E10.5, E13.5, E14.5 and E15.5 WT embryos respectively, Track 5 E14.5 MatDi, Track 6 E15.5 MatDi and Track 7 E15.5 WT. …”

Loss of Trib2 decreases disease latency of Notch-driven T-ALL. by Sarah J. Stein (3168600)

“…<p>A) Kaplan-Meier curve of lethally irradiated mice reconstituted with Trib2^+/+ or Trib2^-/- cells expressing intracellular Notch1 (ICN; “***”, p = 0.0002). Mice with a body condition score of ≤2 and decreased mobility were euthanized (n = 8 Trib2^+/+ and n = 12 Trib2^-/- recipients. …”

Drp1^SD overexpression in Opa1 or Marf depleted type II NBs rescues the reduced mitochondrial membrane potential. by Dnyanesh Dubal (12085942)

“…<p>A, B: Representative images showing decreased TMRM intensity in <i>opa1</i> RNAi and <i>marf</i> RNAi expressing type II NBs. …”

The sialidase inhibitor Neu5Ac2en decreases growth of wt <i>C. canimorsus 5</i> in presence of macrophages. by Manuela Mally (348810)

Flow chart of the expression-based functional screen, with validation steps. by Mohamad Karaky (8910497)

Subjects:

HPV16 E1 decreases cell growth. by Fern Baedyananda (11888703)

Stat1 prevents the decrease of p27^Kip1 by activated Ras. by Shuo Wang (143908)

Anion-Assisted Glycosylation of Galactose: A Computational Study by Kerli Tali (22769704)