<i>Escherichia coli</i> Cyclopropane Fatty Acid Synthase:  Is a Bound Bicarbonate Ion the Active-Site Base?^† by Fabienne Courtois (2667262)

“…The kinetic parameters of the rescued mutants were determined, and it is shown that the rescuing effect is due to an increase in <i>k</i>_cat. These data are interpreted by assuming that the <i>E. coli</i> cyclopropane fatty acid synthase specifically binds a bicarbonate ion that is involved in catalysis, as proposed for the <i>M. tuberculosis</i> enzymes, and that mutation of the bicarbonate ligands decreases the affinity for that ion. …”

<i>Escherichia coli</i> Cyclopropane Fatty Acid Synthase:  Is a Bound Bicarbonate Ion the Active-Site Base?^† by Fabienne Courtois (2667262)

“…The kinetic parameters of the rescued mutants were determined, and it is shown that the rescuing effect is due to an increase in <i>k</i>_cat. These data are interpreted by assuming that the <i>E. coli</i> cyclopropane fatty acid synthase specifically binds a bicarbonate ion that is involved in catalysis, as proposed for the <i>M. tuberculosis</i> enzymes, and that mutation of the bicarbonate ligands decreases the affinity for that ion. …”

G9a decreases Rhox5 expression. by Mayumi Sugimoto (151133)

G9a decreases Rhox5 expression. by Mayumi Sugimoto (151133)

EMBS-treated cells undergo apoptosis correlated with decreased cell viability, metabolic activity and mitochondrial membrane potential. by Michelle Helen Visagie (3927308)

PD 98059 decreases the phosphorylation of ERK in HSVEC, but does not restore ATP-induced decrease in endothelial function in RA. by Padmini Komalavilas (402160)

Decreased immunofluorescence during multiplex staining. by Sandrine Prost (38667)

“…<p>Serial sections were stained with 1 to 5 different markers (Marker 1, MHCII Qdot 705Vivid; Marker 2, HO1 Qdot 605Vivid; Marker 3, CD163 Qdot 565; Marker 4, CD206 Qdot 655Vivid; Marker 5, CD68 streptavidin Qdot 525). …”

Tethering transiently decreases the singing rate. by Homare Yamahachi (363988)

The m⁶A peak of 3’UTR of TLR4 mRNA decreases significantly in METTL14-knockdown PK-15 cells. by Jing Chen (4762)

GSK343 decreased tumor stemness. by Laura V. Bownes (10276762)

“…(C) COA6 cells were treated with GSK343 (0, 5 μM) for 72 hours. qPCR demonstrated a significant decrease in mRNA abundance of known stemness markers Oct4, Nanog, and Sox2 following GSK343 treatment compared to untreated cells. …”

AICD transgenic mice show decreased cell proliferation in the SGZ of hippocampus. by Kaushik Ghosal (244754)

“…<p>Representative images of BrdU immunostaining in the subgranular zone (SGZ) of the dentate gyrus performed on 1.5-mont-old (<b>A</b>) 3-month-old (<b>C</b>) and 12-month old (<b>D</b>) wild-type and FeCγ25 animals one day after the final BrdU injection (100 mg/kg). …”

Decreased tumor size <i>in vivo</i> is achieved by depletion of miR-21 <i>in vitro</i>. by Sara E. Martin del Campo (683602)

A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E ε4 allele-1 by Ryan J Haasl (92283)

“…<p><b>Copyright information:</b></p><p>Taken from "A luteinizing hormone receptor intronic variant is significantly associated with decreased risk of Alzheimer's disease in males carrying an apolipoprotein E ε4 allele"</p><p>http://www.biomedcentral.com/1471-2350/9/37</p><p>BMC Medical Genetics 2008;9():37-37.…”

DAPIT over-expression decreased mitochondrial mass and mtDNA content in DAPIT cells. by Heidi Kontro (768437)

RV-decreases IRAK-1 protein via TLR2 activation. by Benjamin L. Unger (130418)

Activation of GluR5 increased neuronal excitability in interneruons but decreased excitability in pyramidal neurons. by Long-Jun Wu (47043)

“…Resting membrane potential for this neuron was −66.6 mV and the holding current was 66.9 pA. (H) Pooled data showed that ATPA (3 µM) increased firing rate of interneurons (n = 6) while decreased that of pyramidal neurons (n = 5). …”

HDM-specific IgE levels decreased in response to TSLPR ablation in chronic model of asthma mice. by Latifa Koussih (326043)

PD decreases miR-141 levels and the ERK/NF-κB (p65) signaling pathway. by Chuchu Qiao (8831285)

Advanced glycation end-products (AGEs) increased the expressions of RAGE, p38 MAPK, and Bax and decreased the Bcl-2 expression. by Kuo-Cheng Lan (727846)

Colony survival is decreased in 2'-O-ribose <i>trm</i> mutants after exposure to oxidative stress-inducing agents. by Lauren Endres (765718)