Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol by Fabrice E. Graf (469055)

“…Here we describe two different kinds of <i>TbAQP2</i> mutations found in <i>T. b. gambiense</i> field isolates: simple loss of <i>TbAQP2</i>, or loss of wild-type <i>TbAQP2</i> allele combined with the formation of a novel type of <i>TbAQP2/3</i> chimera. The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”

Evaluation of the PCSK9 vaccine (V2 vaccine) in male <i>ApoE-deficient mice</i> (N = 5–7). by Ryo Kawakami (4849549)

miR-214 decreased the number of viable cells and induced apoptosis in HSA cell lines. by Kazuki Heishima (791938)

“…<p>(A) Cell viability was assessed by performing the MTT assay. miR-214-transfection decreased the number of viable cells in HSA cell lines and that of control EC. …”

Estimates of the phenotypic mean, environmental variance (<i>V</i>_<i>E</i>), additive genetic variance (<i>V</i>_<i>A</i>), and heritability (<i>h</i><sup><i>2... by Ryan M. Imrie (15810854)

The m⁶A peak of 3’UTR of TLR4 mRNA decreases significantly in METTL14-knockdown PK-15 cells. by Jing Chen (4762)

Decreased striatal Drd1 mRNA expression during the early, but not late, phase of motor skill learning. by Yu Qian (153240)

<i>In vitro</i> treatment with the broad spectrum caspase inhibitor Q-VD-OPh reduces the number of active caspase-3-positive cells in parallel with a decrease in the entry of micro... by María Martín-Estebané (623506)

Dox-inducible expression of HA-MAD1 in colon is sufficient to decrease p53 expression and cause chromosome missegregation. by Sarah E. Copeland (13951506)

“…Large circles show mean of cells from 5 fields of view from a single animal. …”

Introduction of the D409V point mutation to the <i>GBA1</i> gene does not affect <i>GBA1</i> mRNA transcription or GCase protein translation. by Nicole K. Polinski (10947787)

The Hh signaling pathway effectors are decreased in E14.5 <i>Fuz^−/−</i> mouse embryos. by Zichao Zhang (344301)

“…<p><b>A</b>) Immunofluorescence of Patched1 in sagittal sections of E14.5 <i>Fuz^+/−</i> heterozygous embryos. …”

Apoptosis induction, ROS production and the decrease in MMP by DX1 treatment in HL-60 cells. by Zhiying Yu (356965)

Additional behavioral patterns in the 5€, 100€, and 1000€ treatments. by Pablo Brañas-Garza (336425)

Decrease in <i>Sox2</i> expression results in similar phenotypes as disruptions to FGFR1 signaling. by Lu M. Yang (6919364)

Decreased PGC-1α expression is associated with a hyperglycemia-induced increase in mitochondrial fragmentation and ROS generation. by Kaifeng Guo (296791)

Ameliorative effect of yokukansan on glutamate-induced decrease in GSH levels in PC12 cells. by Hitomi Kanno (584976)

Decreased consumption of methionine sulfoxide (MetO) by the <i>V</i>. <i>cholerae</i> Δ<i>gcvT</i> mutant attenuates virulence by promoting intestinal lipid mobilization and insuli... by Audrey S. Vanhove (4090594)

POS treatment decreases ROS level and upregulates mitochondrial biogenesis in ARPE-19 cells through PGC-1α. by Murilo F. Roggia (755997)

“…<p><b>(A)</b> POS treatment upregulated mRNA levels of anti-oxidant enzymes including GPx1, GPx4, SOD1 and catalase. Mean ± SEM, n = 6 per group, two-tailed Student’s <i>t</i>-test, ** <i>P</i> < 0.01, *** <i>P</i> < 0.001; ns, not significant. …”

Spectral sensitivity (i.e., responses to monochromatic light) of European sea bass. by Richard W. Brill (2337940)

Exposure to LPS decreases insulin, PDX-1 and MafA gene expression in isolated islets via TLR4. by Julie Amyot (167960)

Inhibition of ATR activation significantly decreases B19V-induced G2 arrest in infected CD36⁺ EPCs. by Peng Xu (17962)