Image_3_Complement C5a Induces Pro-inflammatory Microvesicle Shedding in Severely Injured Patients.TIF by Ebru Karasu (5158097)

“…These data suggest a novel role of the C5a-C5aR1 axis: C5a-induced MV shedding from neutrophils results in decreased C5aR1 surface expression on the one hand, on the other hand it leads to profound inflammatory signals which likely are both key drivers of the neutrophil dysfunction which is regularly observed in patients suffering from multiple traumatic injuries.…”

Supplementary Material for: Adult Patients with Hbs-Only Phenotype of Sickle Cell Disease have a Decreased Arginine/Asymmetric Dimethylarginine Ratio by figshare admin karger (2628495)

Replication rate of initial studies depending on the “true” effect and on the sample size. by Estelle Dumas-Mallet (2851265)

Theoretical Study on Reaction Scheme of Silver(I) Containing 5-Substituted Uracils Bridge Formation by Toru Matsui (1313913)

“…The whole reaction scheme is divided into the following three steps: (1) silver ion binding and deprotonation, (2) silver ion transfer, and (3) dimer formation and structural fluctuation. With a new p<i>K</i>_a computing scheme proposed in our previous studies, it is found that a silver coordination decreases the p<i>K</i>_a of <b>N</b> by 2.5–3.0 p<i>K</i>_a units, which is an important clue for silver-ion selectivity by <b>N</b>. …”

BNT162b2- and infection induced reciprocal SARS-CoV-2 nAb titers on wildtype strain wt-BavPat1 and VOC strains Delta, Beta and Omicron at timepoint P1 to timepoint P3. by Olaf Nickel (9524791)

Image_2_Decreased Opioid Consumption in Bone Marrow Harvest Patients Using Quadratus Lumborum Blocks in a Standardized Protocol.PDF by Nicole C. McCoy (12459036)

“…The implementation group showed significantly reduced median intraoperative (20.0 mg vs. 0.0 mg; p < 0.001) and total opioid consumption (20.5 mg vs. 0.0 mg; p < 0.001). The number of patients who received any opioids decreased from 84.2% (16/19) before implementation to 23.1% (3/13) after implementation.…”

Data Sheet 1_Prehospital tranexamic acid decreases early mortality in trauma patients: a systematic review and meta-analysis.docx by Yi Li (1144)

“…Data were pooled under a random- or fixed-effects model using RevMan 5.4 with odds ratio (OR) and 95% confidence interval (CI) as the effect measures.…”

Image_1_Decreased Opioid Consumption in Bone Marrow Harvest Patients Using Quadratus Lumborum Blocks in a Standardized Protocol.PDF by Nicole C. McCoy (12459036)

“…The implementation group showed significantly reduced median intraoperative (20.0 mg vs. 0.0 mg; p < 0.001) and total opioid consumption (20.5 mg vs. 0.0 mg; p < 0.001). The number of patients who received any opioids decreased from 84.2% (16/19) before implementation to 23.1% (3/13) after implementation.…”

Image_3_Decreased Opioid Consumption in Bone Marrow Harvest Patients Using Quadratus Lumborum Blocks in a Standardized Protocol.PDF by Nicole C. McCoy (12459036)

“…The implementation group showed significantly reduced median intraoperative (20.0 mg vs. 0.0 mg; p < 0.001) and total opioid consumption (20.5 mg vs. 0.0 mg; p < 0.001). The number of patients who received any opioids decreased from 84.2% (16/19) before implementation to 23.1% (3/13) after implementation.…”

CDK1 regulates ULK1 phosphorylation independent of ULK1 kinase activity. by Zhiyuan Li (205620)

Screening and Functional Analysis of a Novel Salivary Effector DcE13 from the Asian Citrus Psyllid, Diaphorina citri by Chaozhi Shangguan (16493649)

“…Furthermore, <i>DcE13</i> knockdown decreased survival rates and fecundity of D. citri, as well as interrupted their phloem feeding, indicating its role as an effector that facilitates psyllid feeding. …”

The Mean Prevalence of Infection. by Takele Lakew (34782)

“…Points represent estimates of the prevalence of infection in 1–5 year-old children at a single village-visit. …”

Presentation 1_Loss-of-function mitochondrial DNA polymerase gamma variants cause vascular smooth muscle cells to secrete a diffusible mitogenic factor.pdf by Samantha Rothwell (20733932)

“…Live-cell imaging growth analyses again showed increased growth in A7r5 cells transfected with p.Tyr955Cys but a decreased growth with p.Arg1138Cys, while p.Tyr955Cys increased growth of HeLa cells. …”

A Novel sLRP6E1E2 Inhibits Canonical Wnt Signaling, Epithelial-to-Mesenchymal Transition, and Induces Mitochondria-Dependent Apoptosis in Lung Cancer by Jung-Sun Lee (164985)

“…We designed a Wnt antagonist sLRP6E1E2, and generated a replication-incompetent adenovirus (Ad), dE1-k35/sLRP6E1E2, and a replication-competent oncolytic Ad, RdB-k35/sLRP6E1E2, both expressing sLRP6E1E2. sLRP6E1E2 prevented Wnt-mediated stabilization of cytoplasmic β-catenin, decreased Wnt/β-catenin signaling and cell proliferation via the mitogen-activated protein kinase, and phosphatidylinositol 3-kinase pathways. sLRP6E1E2 induced apoptosis, cytochrome <em>c</em> release, and increased cleavage of PARP and caspase-3. sLRP6E1E2 suppressed growth of the human lung tumor xenograft, and reduced motility and invasion of cancer cells. …”

Expression of c-kit, nNOS, NSE, and PGP9.5. by Ji Eun Kim (403026)

Reducing laminin levels in FCS results in a decrease in BM stiffness. by Ester Molina López (16462735)

Performance of the model with the inhibitory V0_D pathways removed. by Yaroslav I. Molkov (542831)

“…Decreasing <i>α</i> causes two bifurcations: (i) transition from symmetric alternations of flexor activity, i.e. with a phase difference of Δ<i>φ</i> = 0.5, to alternations with a phase difference of Δ<i>φ</i> ≠0.5 at X₇ and then (ii) from alternation to synchronization of flexor activity at X₆. …”

Small decreases in Ca²⁺ influx following exposure to JZL184 in isolated rat islets and INS-1 cells. by Charles A. Berdan (849879)

miRNA profile analysis of ZIKV infected neurons. by Sergio P. Alpuche-Lazcano (10892723)

“…E) miR-7013-5p decreases Nr4a3 mRNA expression. …”

Intraperitoneal hinokitiol injection does not decrease the number of live bacteria in BALF. by Toshihito Isono (8587668)