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point decrease » point increase (Expand Search)
e decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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19681
Substitution of a lysine residue at position 8 of two model 9mer H2-K<sup>b</sup> epitope precursors leads to a marked decrease of N-terminus trimming by ERAP1 <i>in vitro</i>.
Published 2013“…<i>Panels </i><i>D</i><i> and </i><i>E</i>, peptides LVNVDYSKL and the variant LVNVDYSAL (both at 50 µM) were incubated with 15.6 nM of ERAP1 for 1 hr at 37°C and the products analyzed by RP-HPLC. …”
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19682
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19683
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19684
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19685
Different Phenotypes of the Two Chinese Probands with the Same c.889G>A (p.C162Y) Mutation in <i>COCH</i> Gene Verify Different Mechanisms Underlying Autosomal Dominant Nonsyndromi...
Published 2017“…</b> This variant is located in the seventh exon of <i>COCH</i> gene and was identified in the affected members in family #208. …”
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19686
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19687
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19688
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19689
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19690
p300 is a transcriptional coactivator for GR-regulated DUSP1 gene transcription.
Published 2010“…<b>C</b> RNAi against p300 but not CBP decreased DEX-induced DUSP1 gene expression. p300, CBP or scramble (control) siRNA was transfected into A549 cells. 48 h post-transfection, cells were treated with DMSO or DEX (0.5 µM) for 5 h. …”
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19691
Low pH further decreases the F<sup>−</sup>-mediated reduction in protein secretion.
Published 2010“…Gluc activity (secretion) in medium supernatant significantly decreased at pH 6.6 (p<0.05) (F) Cell proliferation, as measured by WST1 assay after 6 hr treatment, did not change significantly, indicating that the observed differences were not due to a proliferative advantage of one treatment group over another, in the short time period examined. …”
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19692
Raw data for male activity.
Published 2023“…<div><p>RNAi targeting the electron transport chain has been proven to prolong life span in many different species, and experiments specifically with <i>Drosophila melanogaster</i> and <i>Caenorhabditis elegans</i> have shown a distinct role for neurons. To determine which subset of neurons is implicated in this life span extension, we used the GAL4/UAS system to activate RNAi against genes of Complex I and Complex V. …”
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19693
Raw data for female fertility.
Published 2023“…<div><p>RNAi targeting the electron transport chain has been proven to prolong life span in many different species, and experiments specifically with <i>Drosophila melanogaster</i> and <i>Caenorhabditis elegans</i> have shown a distinct role for neurons. To determine which subset of neurons is implicated in this life span extension, we used the GAL4/UAS system to activate RNAi against genes of Complex I and Complex V. …”
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19694
Raw data for male sleep.
Published 2023“…<div><p>RNAi targeting the electron transport chain has been proven to prolong life span in many different species, and experiments specifically with <i>Drosophila melanogaster</i> and <i>Caenorhabditis elegans</i> have shown a distinct role for neurons. To determine which subset of neurons is implicated in this life span extension, we used the GAL4/UAS system to activate RNAi against genes of Complex I and Complex V. …”
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19695
Raw data for female starvation.
Published 2023“…<div><p>RNAi targeting the electron transport chain has been proven to prolong life span in many different species, and experiments specifically with <i>Drosophila melanogaster</i> and <i>Caenorhabditis elegans</i> have shown a distinct role for neurons. To determine which subset of neurons is implicated in this life span extension, we used the GAL4/UAS system to activate RNAi against genes of Complex I and Complex V. …”
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19696
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19697
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19698
Effects of Age and Estrogen on Skeletal Gene Expression in Humans as Assessed by RNA Sequencing
Published 2015“…Here we present an RNAseq analysis of human bone samples, obtained from iliac crest needle biopsies, to yield the first <i>in vivo</i> interrogation of all genes and pathways that may be altered in bone with aging and E therapy in humans. 58 healthy women were studied, including 19 young women (mean age ± SD, 30.3 ± 5.4 years), 19 old women (73.1 ± 6.6 years), and 20 old women treated with 3 weeks of E therapy (70.5 ± 5.2 years). …”
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19699
Raw data for male life spans.
Published 2023“…<div><p>RNAi targeting the electron transport chain has been proven to prolong life span in many different species, and experiments specifically with <i>Drosophila melanogaster</i> and <i>Caenorhabditis elegans</i> have shown a distinct role for neurons. To determine which subset of neurons is implicated in this life span extension, we used the GAL4/UAS system to activate RNAi against genes of Complex I and Complex V. …”
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19700
Raw data for female life spans.
Published 2023“…<div><p>RNAi targeting the electron transport chain has been proven to prolong life span in many different species, and experiments specifically with <i>Drosophila melanogaster</i> and <i>Caenorhabditis elegans</i> have shown a distinct role for neurons. To determine which subset of neurons is implicated in this life span extension, we used the GAL4/UAS system to activate RNAi against genes of Complex I and Complex V. …”