Image_1_miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.pdf by Hongkun Qin (10809741)

“…Mechanistically, miR-1258 directly targeted E2F1 in 3’-untranslated regions and attenuated E2F1-mediated downstream gene PCNA and MMP2 transcriptions. …”

Table_6_Splicing Factor DDX23, Transcriptionally Activated by E2F1, Promotes Ovarian Cancer Progression by Regulating FOXM1.xlsx by Chen Zhao (225070)

“…Specifically, DDX23 regulated the mRNA processing of FOXM1. DDX23 silencing reduced the production of FOXM1C, the major oncogenic transcript of FOXM1 in ovarian cancer, thereby decreasing the FOXM1 protein expression and attenuating the malignant progression of ovarian cancer. …”

Table_3_Splicing Factor DDX23, Transcriptionally Activated by E2F1, Promotes Ovarian Cancer Progression by Regulating FOXM1.xlsx by Chen Zhao (225070)

“…Specifically, DDX23 regulated the mRNA processing of FOXM1. DDX23 silencing reduced the production of FOXM1C, the major oncogenic transcript of FOXM1 in ovarian cancer, thereby decreasing the FOXM1 protein expression and attenuating the malignant progression of ovarian cancer. …”

Table_2_Splicing Factor DDX23, Transcriptionally Activated by E2F1, Promotes Ovarian Cancer Progression by Regulating FOXM1.docx by Chen Zhao (225070)

“…Specifically, DDX23 regulated the mRNA processing of FOXM1. DDX23 silencing reduced the production of FOXM1C, the major oncogenic transcript of FOXM1 in ovarian cancer, thereby decreasing the FOXM1 protein expression and attenuating the malignant progression of ovarian cancer. …”

Table_1_miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.docx by Hongkun Qin (10809741)

“…Mechanistically, miR-1258 directly targeted E2F1 in 3’-untranslated regions and attenuated E2F1-mediated downstream gene PCNA and MMP2 transcriptions. …”

Fig 5 - by Piotr Bartków (15348211)

DataSheet_1_Identification of cytochrome P450 gene family and functional analysis of HgCYP33E1 from Heterodera glycines.docx by Jia You (477131)

“…Compared to the control and dsGFP-treated group, silencing of HgCYP33E1 did not affect the J2 behaviors and the early invasion ability, while it decreased the number of J4s in soybean roots after 18-d inoculation with the dsHgCYP33E1-treated nematodes. …”

DataSheet1_Icariside Ⅱ Attenuates Palmitic Acid-Induced Endothelial Dysfunction Through SRPK1-Akt-eNOS Signaling Pathway.PDF by Yang-Yang Gu (11618773)

“…Moreover, inhibition of SRPK1 using SPHINX31 and knockdown of SRPK1 by shRNA also showed a down-regulation of the proteins associated with the SRPK1-Akt-eNOS signaling pathway. …”

Table 1_Effects of icariin as a feed additive on the reproductive function in bucks (Capra hircus).docx by Fang-e Zhao (20140809)

“…However, the serum concentration of GnRH in the ICA group initially increased, followed by a subsequent decrease (p < 0.05). The hypothalamic concentrations of dopamine (DA) and 5-hydroxytryptamine (5-HT) were significantly higher in the ICA group compared to the control group (p < 0.01). …”

Image_3_Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice.TIF by Christa Løth Myhre (7055969)

“…By double in situ hybridization these were shown to be IGF1 mRNA⁺ CD11b mRNA⁺ cells, i.e., IGF-1 mRNA-expressing microglia. …”

Image_2_Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice.TIF by Christa Løth Myhre (7055969)

“…By double in situ hybridization these were shown to be IGF1 mRNA⁺ CD11b mRNA⁺ cells, i.e., IGF-1 mRNA-expressing microglia. …”

Image_8_Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice.TIF by Christa Løth Myhre (7055969)

“…By double in situ hybridization these were shown to be IGF1 mRNA⁺ CD11b mRNA⁺ cells, i.e., IGF-1 mRNA-expressing microglia. …”

Image_4_Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice.TIF by Christa Løth Myhre (7055969)

“…By double in situ hybridization these were shown to be IGF1 mRNA⁺ CD11b mRNA⁺ cells, i.e., IGF-1 mRNA-expressing microglia. …”

Image_7_Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice.TIF by Christa Løth Myhre (7055969)

“…By double in situ hybridization these were shown to be IGF1 mRNA⁺ CD11b mRNA⁺ cells, i.e., IGF-1 mRNA-expressing microglia. …”

Image_6_Microglia Express Insulin-Like Growth Factor-1 in the Hippocampus of Aged APPswe/PS1ΔE9 Transgenic Mice.TIF by Christa Løth Myhre (7055969)

“…By double in situ hybridization these were shown to be IGF1 mRNA⁺ CD11b mRNA⁺ cells, i.e., IGF-1 mRNA-expressing microglia. …”

Representative cases. by Andrey Zhivov (288542)

“…Case 2: 62-year-old female patient, DM duration 7 years, HbA_1c 9.4%, NDS 5 points; Wagner 2 (d), advanced non-proliferative DR (e), moderate decrease in confocal SBP parameters (NFD = 0.010 μm/μm²) (f). …”

Decreased ecdysone signalling in the midgut results in significant decrease in mRNA levels for: <i>cecropin A1</i> (<i>lsmeans(pairwise~Genotype|P0)<0</i>.<i>0001; lsmeans(pairwise... by Catarina Nunes (3542330)

Analyses of membrane currents elicited by depolarizing voltage ramps in EYFP/Panx1 expressing N2a cells. by Sarah Kurtenbach (475817)

“…(<b>F</b>) <i>Tail </i><i>current </i><i>amplitudes </i><i>I</i>_<i>TC</i><i>evoked </i><i>after </i><i>rapid </i><i>hyperpolarization </i><i>from +80 mV </i><i>to -60mV </i><i>after </i><i>the </i><i>first </i><i>depolarizing </i><i>voltage </i><i>ramp </i><i>and</i> (<b>G</b>) <i>time </i><i>at </i><i>which </i><i>the </i><i>tail </i><i>current </i><i>amplitudes </i><i>decreased </i><i>to 50% of its initial value, T</i>_<i>1/2</i><i>, of </i><i>the </i><i>repolarization </i><i>current</i>. …”

Nemp1 KO mice display splenomegaly, blood defects, and erythroid lineage expansion. by Didier Hodzic (132944)

Mitochondrial respiration. by Kaytee L. Pokrzywinski (3605435)