Table4_A-Kinase Anchor Protein 1 deficiency causes mitochondrial dysfunction in mouse model of hyperoxia induced acute lung injury.xlsx by Ramani Soundararajan (651915)

“…Loss of AKAP1, coupled with oxidant injury, significantly decreases the activities of TCA enzymes. Mechanistically, a significant loss of dynamin-related protein 1 (Drp1) phosphorylation at the protein kinase A (PKA) site Serine 637 (Ser637), decreases in Akt phosphorylation at Serine 437 (Ser47) and increase in the expression of pro-apoptotic protein Bax indicate mitochondrial dysfunction. …”

Table2_A-Kinase Anchor Protein 1 deficiency causes mitochondrial dysfunction in mouse model of hyperoxia induced acute lung injury.xlsx by Ramani Soundararajan (651915)

“…Loss of AKAP1, coupled with oxidant injury, significantly decreases the activities of TCA enzymes. Mechanistically, a significant loss of dynamin-related protein 1 (Drp1) phosphorylation at the protein kinase A (PKA) site Serine 637 (Ser637), decreases in Akt phosphorylation at Serine 437 (Ser47) and increase in the expression of pro-apoptotic protein Bax indicate mitochondrial dysfunction. …”

Table1_A-Kinase Anchor Protein 1 deficiency causes mitochondrial dysfunction in mouse model of hyperoxia induced acute lung injury.xlsx by Ramani Soundararajan (651915)

“…Loss of AKAP1, coupled with oxidant injury, significantly decreases the activities of TCA enzymes. Mechanistically, a significant loss of dynamin-related protein 1 (Drp1) phosphorylation at the protein kinase A (PKA) site Serine 637 (Ser637), decreases in Akt phosphorylation at Serine 437 (Ser47) and increase in the expression of pro-apoptotic protein Bax indicate mitochondrial dysfunction. …”

Differential regulation of C5a receptor 1 in innate immune cells during the allergic asthma effector phase by Fanny Ender (3775861)

“…During the allergic effector phase, C5aR1 expression increased in lung tissue eosinophils but decreased in airway and pulmonary macrophages as well as in pulmonary CD11b⁺ conventional dendritic cells (cDCs) and monocyte-derived DCs (moDCs). …”

Frequency compensation in the feedback scheme of Fig 4a for a stepwise change in <i>k</i>₂ at background <i>k</i>₁₀ = 2048.0. by Melissa Nygård (15374507)

Decreased FOXP3 Treg induction in LAG-3 KO T-cells in an <i>in vivo</i> self-tolerance. by Nicholas M. Durham (174371)

Cardamonin decreased the content of free fatty acids and the activity of CPT-1. by Peiguang Niu (17044532)

A breakdown of the CABG/Valve procedure post op care pathways. by Tomi Obafemi (12328433)

Cellular uptake of [¹⁴C]docosahexaenoic acid (DHA) by RBECs transfected with MFSD2A siRNA. by Takuro Iwao (14636741)

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Brain uptake rate of [¹⁴C]docosahexaenoic acid (DHA) in the whole brain and each brain region. by Takuro Iwao (14636741)

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Brain uptake rate of [¹⁴C]sucrose in the whole brain and individual brain regions. by Takuro Iwao (14636741)

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Brain uptake of [³H]mannitol in 2-, 8-, 12-, and 24-month-old mice. by Takuro Iwao (14636741)

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Brain uptake of [¹⁴C]docosahexaenoic acid (DHA) in 2-, 8-, 12-, and 24-month-old mice. by Takuro Iwao (14636741)

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The mRNA expression levels of Mfsd2a in brain microvessels from 2- and 24-month-old mice. by Takuro Iwao (14636741)

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MFSD2A expression levels in brain microvessels from 2-, 8-, 12-, and 24-month-old mice. by Takuro Iwao (14636741)

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Cardamonin decreased the protein level of Raptor and suppressed lipogenesis and CPT-1. by Peiguang Niu (17044532)

Fraction of time, the overall of the studied data trends durations follow a geometric distribution with parameter <i>p</i> = 0.5, and with any <i>p</i>, both cases for a significan... by Héctor Raúl Olivares-Sánchez (13014866)

Rh-endostatin decreases microvascular density (MVD) and promotes vessel normalization of A549 lung carcinoma. by Shujing Shi (422263)

Cdk5 siRNA knockdown decreased Cdk5 activity, diminished WT1 expression and viable cell numbers, and increased cleaved caspase 3 level. by Ya-Li Zheng (454837)

“…After 72h incubation, cells were harvested and submitted to the Western blotting and kinase assay analysis. A&B. Western blots show that Cdk5 siRNA-transfected podocytes successfully decrease Cdk5 expression (upper panel, lane 2) and activity (3rd panel, lane 2 and bar 2, compared to the control siRNA cells, p<0.05), while the expression of cyclin I remain unchanged (2^nd panel). …”

Monte Carlo simulation results for the bSSFP model. by Ki Hwan Kim (427869)