Decreased cell growth of PGRN knock-out cell line as determined by the MTT assay. by Weifeng Zhang (134361)

Fig 5 - by Ke Lu (124270)

Subjects:

Target specificity, <i>in vivo</i> pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma by Peter Y. Yu (4281448)

“…The purpose of this work was to develop and test a novel putative STAT3 inhibitor, LY5.</p><p>Methods and findings</p><p>An <i>in silico</i> fragment-based drug design strategy was used to create LY5, a small molecule inhibitor that blocks the STAT3 SH2 domain phosphotyrosine binding site, inhibiting homodimerization. …”

Nepmucin/CD300LG expression is decreased in tumors and tumor-draining lymph nodes. by Eiji Umemoto (1637)

Jurkat and HeLa survival decreases with increasing electric field amplitude and pulse number. by Bennett L. Ibey (357053)

“…For all exposures, Jurkat cells are more sensitive than HeLa cells. Data points represent the average survival. (mean +/−s.e., n = 3–5).…”

Decreased expression of MHCII in antigen presenting cells from the lungs of IL-19-/- mice. by Carol Hoffman (196241)

Correlations between SARS-CoV-2 specific T cells and FEV₁ and symptoms in PASC. by Katherine M. Littlefield (12647420)

Injection of pNaKtide diminishes PNx-induced decrease in miR-29b-3p expression. by Christopher A. Drummond (3845110)

CsA reduces Flk1 protein expression and significantly decreases the percentages of Flk1+ cells. by Seung-Cheol Choi (686982)

PKCε activation induces aggrecan gene expression, decreases ADAMTS5, and detection of ADAMTS-5-depended cleavage of ECM aggrecan through upregulation of hsa-miR-377 expression. by Emmanouella Tsirimonaki (490707)

“…<p>(<b>A</b>) RT-PCR detected the relative expression of ACAN, MKI67, ADAMTS5 after treatment of NP cells with 1 μM ψεRACK (or vehicle) for indicated times and revealed that time-dependent activation of PKCε significantly increased the mRNA expression for aggrecan, while in an opposing manner decreased ADAMTS5; mRNA levels of the proliferation marker Ki67 became barely detectable after 8 hours of PKCε activation. …”

Foxm1 deletion after tumor initiation decreases lung tumor expansion/progression. by I-Ching Wang (348231)

K-fold cross validation accuracy of different models. by Shayla Naznin (13014015)

Subjects:

Assessment of the protective efficacy of SinH-3 against the bacteremia of multiple ExPEC sequence types (STs). by Yikun Xing (9427893)

I890T markedly decreases peak <i>I</i>_Na. by Anna Tarradas (105463)

CD107a-, IFNγ- and MIP 1β-producing Vγ9Vδ2 T-cell subsets decrease in HIV+ patients. by Rita Casetti (608635)

Decrease of SMAD3 protein, but not SMAD2 in DBA iPSCs. by Jingping Ge (636557)

“…The nuclear p-SMAD2 decreased in <i>RPL5</i> mutant and corrected lines. …”

Mean absolute SHAP values of the most important predictors for APM_MN in each of the five folds of the first repeat. by Shubhayu Bhattacharyay (11242977)

Loss of <i>Otop1</i> decreases BAT maximal mitochondrial respiration in palmitate-rich environment. by Yu-Hsiang Tu (17118218)

Conditional PyLT expression induces cell cycle progression, an increase in cyclin A and a decrease in p21 in ICI treated cells. by Hemant Varma (30590)

Table_2_Dimethylethanolamine Decreases Epileptiform Activity in Acute Human Hippocampal Slices in vitro.docx by Larissa Kraus (7353074)

“…We further tested whether DMEA can exert antiepileptic effects in human brain tissue ex vivo. We analyzed the effect of DMEA on epileptiform activity in the CA1 region of the resected hippocampus of TLE patients in vitro by recording extracellular field potentials in the pyramidal cell layer. …”