Protein kinase A presumably downregulates LAT4 function by increasing its phosphorylation on S274 and decreasing pS297 level. by Lalita Oparija-Rogenmozere (8911535)

Subjects:

Pancreas-Specific Sirt1-Deficiency in Mice Compromises Beta-Cell Function without Development of Hyperglycemia by Andreia V. Pinho (749942)

“…</p><p>Results</p><p>We found that in the Pdx1^Cre; Sirt1^ex4F/F mice, the relative insulin positive area and the islet size distribution were unchanged. …”

Maintenance of a single Zeb2 wt allele rescues PB cytopenia and severe differentiation defects in Zeb1/2 DKO HSPCs. by Jueqiong Wang (11467505)

APB5, but not APA5, decreases apoptosis in alveolar epithelial cells in lungs of BLM-treated mice. by Masami Kishi (6167105)

“…The administration of APA5 did not change the number of TUNEL-positive cells from that in BLM-treated mice, whereas that of APB5 significantly decreased them. …”

HC-070 decreases anxiety after CCK-4 treatment in an EPM. by Stefan Just (4811358)

Sample cases of each type of visual field defect. by Kyoung Min Lee (677987)

<i>Cdkl5</i> -/Y mice show an increased freezing time and a decreased distance traveled during the pretone period in the altered context. by Kosuke Okuda (5150393)

“…<i>Cdkl5</i> -/Y mice show a significantly decreased distance traveled in response to the first footshock (p = 0.0158) compared with control mice. …”

a-c: Proximal tibia (PT) EPO receptor (EPO-R) decreases in uremic rats, as shown by Western blot (Fig. 5a) and immunohistochemistry (Fig. 5b). by Daniel Landau (440830)

“…Animals received a single bolus of IV rhEPO (25 U/kg) or saline, 5 minutes prior to sacrifice. …”

Establishing environmental soil phosphorus thresholds to decrease the risk of losses to water in soils from Rio Grande do Sul, Brazil by Luciano Colpo Gatiboni (4619761)

Pharmacological inhibition of EGFR decreases early fungal burden and reduces the inflammatory response. by Marc Swidergall (185453)

Number of trees at the end time resulting from simulation of the optimal control P3 with <i>ω</i>₁ = 1, <i>ω</i>₂ = .5, <i>ω</i>₃ = .1 and <i>u</i>... by Maria C. A. Leite (5586701)

Identification of small molecules that inhibit viral M mRNA nuclear export and/or decrease viral M mRNA levels. by Matthew Esparza (8661219)

“…<p>(<b>A</b>) Representative images showing uninfected cells; cells infected with A/WSN/33 and pretreated with 0.5% DMSO (control), which show viral M mRNA exported into the cytoplasm, in red; and cells infected with A/WSN/33 pre-treated with 2.5 μM of the transcription inhibitor DRB (5,6-dichloro-1-β-D-ribofuranosylbenzimidazole). …”

NOTCH signaling is upregulated upon mycobacterial infection. by Salik Miskat Borbora (9381455)

Subjects:

E3 ubiquitin ligase ITCH (AIP4) repression aids in Mtb-mediated enhanced lipid accumulation. by Salik Miskat Borbora (9381455)

Subjects:

A <i>mer2</i> point mutant affected for its interaction with Spp1 mimics the meiotic phenotype of <i>spp1∆</i>. by Céline Adam (320770)

Decrease in gastrin-, histidine decarboxylase-, and somatostatin mRNA due to the <i>H. pylori</i> B128 WT-infection. by Tobias Wiedemann (266622)

Cells expressing nsP2 inefficiently present antigen and have decreased levels of cell surface MHC-I. by Brian C. Ware (8544672)

FFA treatment for 48 hours induced decrease of IFNAR1 in Huh-7.5 cells is mediated by a lysosomal degradation pathway. by Ramazan Kurt (449801)

Decreased expression of the γ-glutamylcysteine ligase and increased hepatic oxidant generation and protein oxidative damage at Day+4 in Allo BMT. by Jung H. Suh (523844)

METH decreased basal pERK1/2 levels and potentiated ERK1/2 phosphorylation induced by 6-OHDA. by Amina El Ayadi (341955)

“…METH decreased activation of ERK 1/2 in a concentration-dependent manner (0, 0.5, and 1 mM at the 24 hr time point) and enhanced the activation of ERK1/2 after 6-OHDA exposure. …”