Effects of isobavachalcone treatment on BV-2 cells and Neuro-2a cells. by Haoran Jing (3621779)

“…C: Isobavachalcone decreased microglial-induced neuro-2a death in a co-culture system. …”

Description of the role of the pharmacist in a multiprofessional team focused on the care of hospitalized elderly by Isabela Vaz Leite Pinto (12817700)

“…A total of 163 pharmaceutical interventions were carried out, representing a mean of 6.79 interventions/patient and 82.2% acceptance. …”

Epidemiology of Orbital and Preseptal Cellulitis in the United States: A 13-Year Analysis by Shazia Dharssi (20563728)

“…Young adults (ages 21–44) comprise a majority of patients with either preseptal or orbital cellulitis (31.7%; 95% CI, 30.5–33.0%). …”

Data_Sheet_1_Are Reduced Levels of Coagulation Proteins Upon Admission Linked to COVID-19 Severity and Mortality?.PDF by Francisco C. Ceballos (8065037)

Icaritin and lenvatinib treatment for unresectable localized progressive pancreatic cancer: a report of six cases by Xiaolong Liu (265696)

“…Partial responses were observed in cases 1 and 3, with some tumor shrinkage. Cases 4 and 5 showed limited relief following a slight decrease in tumor size. …”

Causal relationships between interleukins, interferons and COVID-19 risk: a Mendelian randomization study by Chao Wang (146527)

“…Finally, sensitivity analyses were applied to assess the robustness of results. As a result, one IFN (IFN-W1) and five ILs (IL-5, IL-6, IL-13, IL-16 and IL-37) were identified to significantly decrease the COVID-19 risk. …”

DataSheet_1_Reduced prevalence of drug-related problems in psychiatric inpatients after implementation of a pharmacist-supported computerized physician order entry system - a retro... by Katharina Wien (18330384)

“…To date, no study has been reported on the types and prevalence of drug-related problems (DRPs) before and after CPOE implementation in a psychiatric inpatient setting. The aim of this retrospective before-and-after cohort study was to investigate whether the implementation of a CPOE system with CDSS accompanied by the introduction of regular medication plausibility checks by a pharmacist led to a decrease of DRPs during hospitalization and unsolved DRPs at discharge in psychiatric inpatients.…”

B28Bn(6–14)-induced loss of mitochondrial transmembrane potential. A by Hao Yang (328526)

The representative trace of the LDF signal after the intravital injection of ADP to a mouse (a), parameters of the curve calculated by PAMA software, the LDU values are multiplied... by Tomasz Przygodzki (4277908)

“…<p>The following parameters characterizing the curve were calculated using PAMA software, as described in ‘<i>Materials and Methods</i>’ and are expressed in arbitrary Laser Doppler Flow units (LDU): <b>A</b>_<b>max</b><b>—</b>the maximum decrease in blood flow with respect to the baseline; <b>DA–</b>the maximal restoration of flow with respect to the baseline; <b>T</b>_<b>d</b><b>—</b>time from the injection of ADP to 10% of the maximum decrease in blood flow (A_max); <b>T</b>_<b>r</b><b>−</b>time from 10% to 90% of the maximum decrease in blood flow (A_max); <b>T</b>_<b>c</b><b>−</b>time from 90% of A_max to 90% of DA; <b>T</b>_<b>f</b><b>−</b>time from 90% of DA to 10% of DA; <b>V</b>_<b>0r</b><b>–</b>the maximal rate of the decrease in blood flow; <b>V</b>_<b>Avgr</b><b>−</b>the rate of decrease averaged through T_r; <b>V</b>_<b>0f</b><b>–</b>the maximal rate of the restoration of blood flow; <b>V</b>_<b>Avgf</b><b>−</b>the rate of restoration averaged through T_f; <b>AUC–</b>the area under the curve from 10% of A_max to 10% DA; <b>AUC</b>_<b>r</b><b>−</b>the area under the curve from 10% to 90% of A_max; <b>AUC</b>_<b>c</b><b>−</b>the area under the curve from 90% of A_max to 90% of DA; <b>AUC</b>_<b>f</b><b>−</b>the area over the curve from 90% to 10% of DA.…”

Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

Protein-protein docking for Parkin and a charged E2∼Ub complex. by Thomas R. Caulfield (655752)

“…The docking in the same position is shown and rotated 180° to reveal the other side. Residues of the Ubch5a-Ub complex are indicated by color (dark green and brown, respectively). …”

Cerebral Venous Sinus Thrombosis - Diagnostic Strategies and Prognostic Models: A Review by Penka A. Atanassova (7944506)

“…Patients with CVST commonly present with headache, although some develop a focal neurological deficit, decreased level of consciousness, seizures, or intracranial hypertension without focal neurological signs. …”

Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

A review of grass species yields and growth rates in Northland, New Zealand by Carmen S. P. Teixeira (9938331)

“…The medium-term prospect suggests an urgent need to improve research into management of cocksfoot and tall fescue-based pastures to provide viable alternatives to overcome the decreasing persistence of perennial ryegrass.</p> <p><a href="https://www.tandfonline.com/pb-assets/tandf/Migrated/Video_Transcript_TNZA_2351614.pdf" target="_blank">Read the transcript</a></p> <p><a href="https://vimeo.com/964566516" target="_blank">Watch the video on Vimeo</a></p> <p>© 2024 The Author(s). …”

The Effect of Chronic Stress on Apoptosis Regulation and Oncogenesis Evolution: A Theoretical Approach. by DIMITRIOS KIMOGLOU (20499350)

Influence of natural gas composition on adsorption in calcite Nanopores: A DFT study by Elbashier E.

“…The nanopores absorbed up to 28 and 24 molecules of CH4 and CO2, respectively, and the adsorption energy decreased to −0.0062 and −0.0075 eV/Å2 for each. Although the nanopore was filled spatially by the molecules, its surface still has an affinity to absorb more gas molecules energetically. …”
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Pyrvinium inhibits WNT signaling in a CK1α dependent manner. by Bin Li (39349)

“…<p><b>A</b>. The expression of the WNT target gene: <i>AXIN2</i> was determined from NIH 3T3 cells expressing control or <i>CK1α</i>-specific shRNAs. …”

Supplementary Material for: Differential Impact of Cognitive Impairment in MCI Patients: A Case-Based Report by Pergher V. (9038528)