Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer by Xiaoming Chen (230202)

“…Here, we reported a novel compound corallorazine D from <i>Nocardiopsis</i> sp. …”

Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer by Xiaoming Chen (230202)

“…Here, we reported a novel compound corallorazine D from <i>Nocardiopsis</i> sp. …”

Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer by Xiaoming Chen (230202)

“…Here, we reported a novel compound corallorazine D from <i>Nocardiopsis</i> sp. …”

Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer by Xiaoming Chen (230202)

“…Here, we reported a novel compound corallorazine D from <i>Nocardiopsis</i> sp. …”

Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer by Xiaoming Chen (230202)

“…Here, we reported a novel compound corallorazine D from <i>Nocardiopsis</i> sp. …”

Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer by Xiaoming Chen (230202)

“…Here, we reported a novel compound corallorazine D from <i>Nocardiopsis</i> sp. …”

Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer by Xiaoming Chen (230202)

“…Here, we reported a novel compound corallorazine D from <i>Nocardiopsis</i> sp. …”

Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer by Xiaoming Chen (230202)

“…Here, we reported a novel compound corallorazine D from <i>Nocardiopsis</i> sp. …”

Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer by Xiaoming Chen (230202)

“…Here, we reported a novel compound corallorazine D from <i>Nocardiopsis</i> sp. …”

Natural Derivatives of Selective HDAC8 Inhibitors with Potent <i>in Vivo</i> Antitumor Efficacy against Breast Cancer by Xiaoming Chen (230202)

“…Here, we reported a novel compound corallorazine D from <i>Nocardiopsis</i> sp. …”

Growth curve of a representative patient. by Dalit Modan-Moses (307368)

Selective Peptidomimetic Inhibitors of NTMT1/2: Rational Design, Synthesis, Characterization, and Crystallographic Studies by Brianna D. Mackie (9212677)

“…Its cell-permeable analogue <b>DC432</b> (IC₅₀ of 54 ± 4 nM) decreases the N-terminal methylation level of the regulator of chromosome condensation 1 and SET proteins in HCT116 cells. …”

Loop in the IB domain drives ParM monomer opening. by Natalie Ng (6560246)

“…Two simulations (ParM-ATP-2,3) consistently exhibited opening angles of ~102° after 50 ns and maintained that value, whereas in the other simulation (ParM-ATP-1), the opening angle increased beyond 105° after 100 ns and then eventually decreased to ~103° in the last 20 ns of the 200-ns simulation (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006683#pcbi.1006683.s004" target="_blank">S4A Fig</a>). …”

Notch signaling regulates the responses of lipopolysaccharide-stimulated macrophages in the presence of immune complexes by Wipawee Wongchana (5367968)

“…A similar impact on IL-10 production was observed when Notch signaling was inhibited with a gamma-secretase inhibitor (GSI). …”

Evaluation of Efficiency of Liposome-Entrapped Iridium(III) Complexes Inhibiting Tumor Growth In Vitro and In Vivo by Huiyan Hu (9376570)

“…In addition, we also found that 3alip, 3blip, and 3clip triggered ferroptosis and autophagy. …”

Rotational Periodicity Display of the Tunable Wettability Pattern in a Photoswitch Based on a Response Bilayer Photonic Crystal by Yong Qi (429532)

FLP-1 peptides modulate locomotion. by Ingrid Buntschuh (4729536)

“…<p>Loss of <i>flp-1</i> causes hyperactivity, while overexpression of <i>flp-1</i> decreases activity. …”

Characterization of hematopoietic stem and progenitor cells from BM of young and aged KO-F mice vs. by Ling Tian (107492)

Minidysferlin do not improve muscle histology. A by William Lostal (162211)

“…It should be noted that this fold correspond to a mean expression and that each individual fiber can express more or less than this means. …”

Summary of the effect of maternal immune activation on serotonin and dopamine. by Pei-Tan Hsueh (752475)

“…Moreover, the total number and distribution of tph2-expressing 5-HTergic neurons, and the diameter of the 5-HTergic axon hillocks were decreased at the age of 8 weeks. We concluded that maternal immune activation induced by exposure to a low dose of LPS decreased cerebral 5-HT in parallel with the down-regulation of 5-HT-related genes (tph2 and slc6a4), resulting in anxiety-like behavior in the female offspring.…”