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Ether induces proteotoxic stress, leading to a decrease in Trx protein and an increase in Hsp90 clients that are joint targets of Trx and Ubx.
Published 2024“…<b>(F)</b> Representative images of Acridine Orange-stained <i>yw</i> embryos for the following cases: no treatment (up left), 5-min immersion in Citrasolv solution [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002629#pbio.3002629.ref046" target="_blank">46</a>] (up right), 5-min immersion in ether liquid (bottom right), and 1.5-h exposure to ether vapor (bottom left). …”
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Genes whose expression was decreased in RASMC subjected to Na<sup>+</sup>,K<sup>+</sup>-ATPase inhibition.
Published 2014“…Listed are assigned genes whose expression was decreased in K<sup>+</sup>-free medium by more than 3-fold and was different by less than 2-fold in the presence of ouabain compared to K<sup>+</sup>-free medium. …”
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TGFβ1 expression was increased, and RASAL1 expression was decreased in NTM cells in response to a hypoxic environment.
Published 2016“…</b> After 24 hours, RASAL1 was decreased; fold change 0.51+/-0.13 (P<0.05). …”
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Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T...
Published 2022“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC<sub>(tofacitinib, 0–∞)</sub> and a 9.61-fold increase of colonic AUC<sub>(tofacitinib, 0–12h)</sub>, compared with tofacitinib at a molar equivalent oral dose. …”
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