Molecular Dynamics Characterization of Five Pathogenic Factor X Mutants Associated with Decreased Catalytic Activity by Safwat Abdel-Azeim (153436)

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Flowchart of the analysis steps and methods used in the study (see details in sections 2.1 to 2.5). by Juan David Gutiérrez (6511763)

5-HT- induced mitochondrial ROS inhibits <i>P</i>. <i>berghei</i> infection. by Li Gao (131516)

How Do Zn²⁺ Ions Promote Methane Activation on Zinc-Modified Zeolites? A Hybrid Quantum-Chemical Study by Zoya N. Lashchinskaya (8102741)

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NMP inhibits the incorporation of ¹⁴C-palmitic acid into glycopeptidolipids, phosphatidylethanolamine and cardiolipin in <i>M</i>. <i>abscessus</i>. by Timilehin Faboro (20175963)

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MMP-2 production is decreased following ALK5 inhibition. by Rebecca A. Scott (488956)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

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Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

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UNC-62 RNAi decreases expression of collagen genes and increases expression of intestinal genes. by Eric L. Van Nostrand (30730)

“…The histogram indicates the distribution of genes by average fold-change upon <i>unc-62</i> RNAi. For 1699 genes with intestine-enriched expression <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-McGhee1" target="_blank">[23]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Pauli1" target="_blank">[33]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Spencer1" target="_blank">[34]</a> as well as the subset of 291 genes that also decrease expression with age <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Budovskaya1" target="_blank">[10]</a>, we determined the average mean-centered fold-change from triplicate RNA-seq experiments of <i>unc-62</i> RNAi as compared to controls. …”

Proinflammatory signaling pathways were decreased in Ad26.COV2.S vaccinated compared to sham unvaccinated hamsters. by Malika Aid (7303874)

“…<p><b>(A)</b> Boxplots of SARS-CoV-2 transcripts normalized read counts across all animals, vaccinated hamsters are shown in blue and pink, and sham animals in green. …”

The influence of 5-HT in mice serum on <i>Plasmodium</i> infection in mosquitoes. by Li Gao (131516)

<i>Ang1</i>-deficient mice are associated with alterations in the gut microbiome. by Alexander Hu (14755811)

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PDGF-BB-induced NR4A1 expression is decreased after treatment with the NF-κB inhibitor BAY11-7082. by Glenda Eger (636934)

L665W decreased AR5A binding to H77/JFH1 particles and to the E1/E2 complex in H77/JFH1 infected cells, but did not alter receptor dependency. by Rodrigo Velázquez-Moctezuma (3776023)

A C5a-Immunoglobulin complex in chronic lymphocytic leukemia patients is associated with decreased complement activity by Regina Michelis (2889092)

“…In patients with abnormal C5, basal levels of sC5b-9 and C5a were increased while activities of the CP and of the CP C5-convertase, the immediate C5-upstream complex, were decreased compared to NC and to patients with normal C5. …”

Patients with NDO have decreased BKα subunit mRNA expression in DSM. by Kiril L. Hristov (431003)

“…<p>qPCR analyses showing 15.8-fold, 1.1-fold, and 1.6-fold decreases in BKα (<b>A</b>), BKβ1 (<b>B</b>), and BKβ4 subunits (<b>C</b>) mRNA expression in NDO DSM tissue (n = 3, N = 3) compared to controls (n = 7, N = 7; **P<0.01). …”

Flies decrease the level of aggression as the availability of food resource increases. by Rod S. Lim (622045)

Immunohistochemistry of the Kv11.1 channels in the placental arteries of women who gave birth without or with COVID-19 during pregnancy. by Sergiy G. Gychka (13175728)

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Gene Ontology analysis reveals biological programs that are decreased during vertebrate tissue regeneration. by Sarah E. Mercer (108441)

Pathway-Express (PE) performs a pathway level impact analysis and orders the affected pathways in the decreasing order of their expected importance for the given condition (panel 1... by Purvesh Khatri (19219)