Tenfibgen Ligand Nanoencapsulation Delivers Bi-Functional Anti-CK2 RNAi Oligomer to Key Sites for Prostate Cancer Targeting Using Human Xenograft Tumors in Mice by Janeen H. Trembley (644906)

“…The sub-50 nm size TBG nanocapsule (s50-TBG) is a slightly negatively charged, uniform particle of 15 - 20 nm size which confers protection to the nucleic acid cargo. …”

The effect of stretch on the MAP of the fish heart. by Simon M. Patrick (364948)

“…MAPD is shown at MAPD25 (A,D), MAPD50 (B,E) and MAPD90 (C,F) (mean ± S.E.M, <i>p</i><0.05). …”

Independent model predictions versus experimental observations. by Ryan Tasseff (253998)

“…The ensemble predicted an approximate 50% decrease in androgen stimulated PSA expression due to AR knock-down 72 hours after treatment. …”

Morphological changes in NFs for RF-induced rat sciatic nerve injury. by Samjin Choi (358532)

“…CO, control; SH, sham; PRF, pulsed RF; CRF, continuous RF. Scale bar = 50 µm. (B) Definition of NFs for counting. M, myelin; A, axon. …”

Flavaglines Alleviate Doxorubicin Cardiotoxicity: Implication of Hsp27 by Yohann Bernard (198579)

“…Administration of our lead compound (FL3) to mice attenuated cardiomyocyte apoptosis and cardiac fibrosis, as reflected by a 50% decrease of mortality.</p> <h3>Conclusions/Significance</h3><p>These results suggest a prophylactic potential of flavaglines to prevent doxorubicin-induced cardiac toxicity.…”

Requirement of viral DNA replication for sT-mediated late gene reporter activation in MCV reporter viral genomes. by Kyle Rapchak (13833941)

“…<b>(B)</b> Quantification of late gene-driven ZsG positive cells (top panel) and mean fluorescence intensity (bottom panel). Cells obtained from 6 independent transfections were analyzed by flow cytometry. sT deletion does not significantly decrease ZsG positive cells whereas introducing a mutation into the NCCR (MCVΔsT.L-ZsG_rep-) decreased percent positivity by 50%. …”

Datasheet1_Outcomes among patients undergoing transcatheter aortic valve replacement with very low baseline gradients.docx by Faisal Rahman (11048519)

“…Background<p>While there is evidence that patients with low-flow, low-gradient aortic stenosis (AS) benefit from transcatheter aortic valve replacement (TAVR), data are lacking regarding outcomes of patients with a very low gradient (VLG).</p>Methods<p>In this retrospective, single-center study of patients with severe AS who underwent TAVR, three groups were defined using baseline mean aortic valve gradient: VLG (≤25 mmHg), low gradient (LG, 26–39 mmHg), and high gradient (HG, ≥40 mmHg). …”

Period of latency, progression and duration of blockade of epidural anesthesia with lidocaine, bupivacaine or its association in dogs by S.J. Ronchi (8143470)

Simulated models of motion can be differentiated based on Heteromotility features. by Jacob C. Kimmel (4768185)

“…<p>(A) Representative t-SNE visualization of Heteromotility feature space determined for simulated motion models (1000 members/class, 100 time steps)(perplexity = 50). …”

Data_Sheet_1_Collateral impact of the COVID−19 pandemic on the use of healthcare resources among people with disabilities.PDF by Minjeong Sohn (13191558)

Data_Sheet_2_Collateral impact of the COVID−19 pandemic on the use of healthcare resources among people with disabilities.PDF by Minjeong Sohn (13191558)

<em>Tbx6</em> Regulates Left/Right Patterning in Mouse Embryos through Effects on Nodal Cilia and Perinodal Signaling by Anna-Katerina Hadjantonakis (16088)

Volcano plots of molecular interaction signatures. by Michael Römer (564122)

“…As a formal criterion for a putative molecular interaction, we required that for both interaction partners a 50% increase or decrease in expression could be observed relative to the controls.…”

Poly(ADP-Ribose) Polymerase 1 (PARP-1) Regulates Ribosomal Biogenesis in <em>Drosophila</em> Nucleoli by Ernest K. Boamah (189447)

“…Substantial amounts of PARP1 and pADPr (up to 50%) are localized to the nucleolus, a subnuclear organelle known as a region for ribosome biogenesis and maturation. …”

Data_Sheet_5_Sestrin2-Mediated Autophagy Contributes to Drug Resistance via Endoplasmic Reticulum Stress in Human Osteosarcoma.ZIP by Zhen Tang (2977569)

Data_Sheet_2_Sestrin2-Mediated Autophagy Contributes to Drug Resistance via Endoplasmic Reticulum Stress in Human Osteosarcoma.ZIP by Zhen Tang (2977569)

Caveolae-Mediated Endocytosis Drives Robust siRNA Delivery of Polymeric Nanoparticles to Macrophages by Yudong Song (10725858)

Data_Sheet_12_Sestrin2-Mediated Autophagy Contributes to Drug Resistance via Endoplasmic Reticulum Stress in Human Osteosarcoma.ZIP by Zhen Tang (2977569)

Data_Sheet_14_Sestrin2-Mediated Autophagy Contributes to Drug Resistance via Endoplasmic Reticulum Stress in Human Osteosarcoma.ZIP by Zhen Tang (2977569)

Image_3_Sestrin2-Mediated Autophagy Contributes to Drug Resistance via Endoplasmic Reticulum Stress in Human Osteosarcoma.TIF by Zhen Tang (2977569)