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Cinacalcet administered early in the inactive phase markedly decrease parathyroid Ki-67 index.
Published 2025Subjects: -
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Deletion of Hhp2 markedly increased Sre1 activity.
Published 2020“…<p>Deletion of <i>hhp2</i><sup>+</sup> gene markedly increased Sre1 activity in the presence/absence of CLZ (2 μg/ml to 8 μg/ml) (A), TER (2 μg/ml to 8 μg/ml) (B) or CoCl<sub>2</sub> (0.08 mM to 0.32 mM) (C). …”
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ALS patients’ tissues exhibit increased phosphorylation of MARK2.
Published 2021“…<p>(<b>A</b>) Representative immunoblot analyses of PKCδ, MARK2-<sup>595</sup>T, and eIF2α in the spinal cord tissues from ALS patients and non-ALS controls, indicating that increased phosphorylation of PKCδ-<sup>505</sup>T, MARK2-<sup>595</sup>T, and eIF2α-<sup>51</sup>S is a general phenotype in patient tissues. …”
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Withdrawal of Type I JAKinibs increased STAT phosphorylation, a phenomenon present but markedly lower in Type II JAKinibs.
Published 2025“…(A) pJAK2 peaked at time zero after exposure to baricitinib and ruxolitinib and then decreases. …”
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The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients.
Published 2020“…Results show that, in normal crypts, the distribution and proportion of cells staining for ALDH1 and CGA are very similar. In contrast, in <i>APC</i>-mutant tissues from FAP patients, the proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases. …”
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Chronic colitis induces marked changes in protein expression in the adult heart and blood.
Published 2021“…<p>(A) Expression levels of proteins indicated in the tissue lysates of myocardium were significantly altered by DSS-induced chronic colitis. …”
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Increased lipid accumulation and decreased klotho expressions in palmitate-treated mouse podocytes.
Published 2021“…<p>(a and b) Representative Oil-Red O staining from diabetic human kidney biopsies (a) and palmitate-treated mouse podocytes (b) demonstrating the increased lipid accumulation. …”
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Decreased ISCs and increased goblet cells after intestinal specific loss of MLL1.
Published 2021“…<p><b>(A)</b> Kaplan-Meier survival curve. Tamoxifen was given by gavage for 6 days to mice with the genotype <i>Mll1</i><sup><i>FC/+; Vil-Cre-ERT2/+</i></sup> (n = 12) and <i>Mll1</i><sup><i>FC/FC; RC/+</i></sup> (n = 18). …”
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Variable importance plot (mean decrease accuracy and mean decrease Gini).
Published 2020“…The variables are presented from descending importance. The mean decrease in Gini coefficient is a measure of how each variable contributes to the homogeneity of the nodes and leaves in the resulting random forest. …”
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Evogliptin attenuates the phenotypic switch of VSMCs during CER treatment by decreasing the osteogenesis-associated genes <i>in-vitro.</i>
Published 2025“…<p>(A) Representative images showed calcium deposition (red). …”