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a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Deletion of Hhp2 markedly increased Sre1 activity.
Published 2020“…<p>Deletion of <i>hhp2</i><sup>+</sup> gene markedly increased Sre1 activity in the presence/absence of CLZ (2 μg/ml to 8 μg/ml) (A), TER (2 μg/ml to 8 μg/ml) (B) or CoCl<sub>2</sub> (0.08 mM to 0.32 mM) (C). …”
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ALS patients’ tissues exhibit increased phosphorylation of MARK2.
Published 2021“…<p>(<b>A</b>) Representative immunoblot analyses of PKCδ, MARK2-<sup>595</sup>T, and eIF2α in the spinal cord tissues from ALS patients and non-ALS controls, indicating that increased phosphorylation of PKCδ-<sup>505</sup>T, MARK2-<sup>595</sup>T, and eIF2α-<sup>51</sup>S is a general phenotype in patient tissues. …”
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Increased phosphorylation of MARK2 occurs in the affected tissues of a mutant SOD1-induced ALS mouse model.
Published 2021“…(<b>B</b>) Immunoblot analyses of spinal cords from symptomatic SOD1<sup>G93A</sup> mice and NTg littermate controls indicate that the level of phosphorylated PERK-<sup>980</sup>T was significantly increased in the SOD1<sup>G93A</sup> mice, while no change was detected for GCN2. …”
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The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients.
Published 2020“…Results show that, in normal crypts, the distribution and proportion of cells staining for ALDH1 and CGA are very similar. In contrast, in <i>APC</i>-mutant tissues from FAP patients, the proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases. …”