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Proteasome activity was decreased in the <i>myc-rpt6-S119A</i> mutant.
Published 2017“…The mean ± SEM rate of Suc-LLVY-AMC cleavage is decreased in the <i>myc-rpt6-S119A</i> mutant compared to the WT and <i>myc-rpt6-S119D</i> strains. …”
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Expression of ApoB-50 decreased lipid accumulation and inhibited HCV production.
Published 2021Subjects: -
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Diabetic kidney shows decreased klotho expression.
Published 2021“…<p>(a) Representative images of the kidney from normal and diabetic biopsies showing the decreased klotho expression in diabetic podocytes by IHC. …”
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Does Mean Platelet Volume Decrease in the presence of Coronary Artery Fistula?
Published 2019“…Compared to the control group, median (IQR) High-density lipoprotein cholesterol (HDL) levels were significantly higher (p=0.04) and MPV levels were significantly lower in the CAF group (8.84 ± 1.71fL vs. 10.43 ± 1.34, p < 0.001). In the multivariate analysis, only MPV was a significant predictor of CAF (p < 0.001, 95% CI for OR: 0.438 (0.306-0.629). …”
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FTY720 treatment decreased tumor growth in a xenograft model of hepatoblastoma.
Published 2019Subjects: -
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Expression of neurotrophins and their receptors was decreased in <i>Slitrk6</i>-deficient inner ear.
Published 2009“…The graphs depict mean + SD of 3 independent analyses. The mRNAs of <i>Bdnf</i> and <i>Ntf3</i> were significantly decreased in <i>Slitrk6</i>-deficient inner ear, whereas those of <i>Ntrk2</i> and <i>Ntrk3</i> were not. * <i>p</i><0.05, Student's <i>t</i>-test. …”
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Zebrafish harboring homozygous mutations in <i>gdf6</i> exhibit decreased endurance.
Published 2014“…<p><b>A. </b><i>gdf6<sup>−/−</sup></i> fish have a lower endurance compared to <i>gdf6<sup>+/+</sup></i> siblings as measured by increasing water velocity in a swim channel to determine the <i>U</i><sub>crit</sub> i.e. …”
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Decreased expression of adipogenesis-related genes by baicalein in early stage of adipogenesis.
Published 2016“…<p>A, Expression levels of the adipogenic and lipogenic genes. 3T3-L1 cells (undifferentiated cells: U; <i>white columns</i>) were differentiated into adipocytes (differentiated cells: D) for 6 days in DMEM in the absence (<i>gray columns</i>) or presence (50 μM; <i>black columns</i>) of baicalein during days 0–2 or 0–6. …”
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<i>Kdm6a</i> conditional KO mice have decreased repopulating potential in serial competitive transplantation assays.
Published 2021“…Whole BM cells were harvested from all cohorts of young <i>Kdm6a</i> conditional KO mice (CD45.2) and mixed with WT competitor marrow (CD45.1 x CD45.2) in a 1:1 ratio, which was then transplanted into lethally-irradiated primary recipient mice (CD45.1). …”