Supplementary Material for: Impairment of Renal Function in Hermansky-Pudlak Syndrome by Yokoyama T. (4606381)

“…Introduction Hermansky-Pudlak syndrome (HPS) is a rare autosomal recessive disorder characterized by defective biogenesis of lysosome-related organelles. …”

Supplementary Material for: Clinical Assessment of Continuous Hemodialysis with the Medium Cutoff EMiC<b>®</b>2 Membrane in Patients with Septic Shock by Ferrari F. (4177876)

“…Leukocytosis improved over 24 h in EMiC®2-CVVHD-treated patients (β = 4.13; <i>p</i> = 0.03), whereas procalcitonin levels decreased regardless of the modality (β = 0.89; <i>p</i> = 0.01) over a 48-h treatment period. …”

Image_6_Modulatory actions of Echinococcus granulosus antigen B on macrophage inflammatory activation.jpeg by Ana Maite Folle (3613004)

“…., one of these lipoproteins is antigen B (EgAgB), codified by a multigenic and polymorphic family that gives rise to five gene products (EgAgB8/1-5 subunits) assembled as a 230 kDa macromolecule. …”

Data_Sheet_1_Dietary Phospholipids Prepared From Scallop Internal Organs Attenuate the Serum and Liver Cholesterol Contents by Enhancing the Expression of Cholesterol Hydroxylase i... by Koki Sugimoto (11611486)

“…Therefore, this study showed that SCO-PL may be a health-promoting component as it lowers the serum and liver cholesterol contents by increasing the liver CYP7A1 expression, which is not seen in SOY-PL and SCO-TG.…”

Data Sheet 1_Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.csv by Qingzhu Liang (22315633)

“…Gene expression was associated with immune cell infiltration: HCM samples showed increased CD4+ T cells and M0 macrophages but decreased M2 macrophages and neutrophils. The ceRNA network comprised 5 mRNAs, 40 miRNAs, and 152 lncRNAs. …”

Data_Sheet_1_Long-term gamma transcranial alternating current stimulation improves the memory function of mice with Alzheimer’s disease.ZIP by Linyan Wu (13797970)

“…Based on this issue, we investigated the effect of gamma frequency (40 Hz) tACS at different durations in a mouse model of AD.</p>Materials and methods<p>We placed stimulating electrodes on the skull surface of APP/PS1 and wild-type control mice (n = 30 and n = 5, respectively). …”

Image_4_Modulatory actions of Echinococcus granulosus antigen B on macrophage inflammatory activation.jpeg by Ana Maite Folle (3613004)

“…., one of these lipoproteins is antigen B (EgAgB), codified by a multigenic and polymorphic family that gives rise to five gene products (EgAgB8/1-5 subunits) assembled as a 230 kDa macromolecule. …”

Demographic characteristics of livebirths. by Jackie K. Patterson (13878632)

“…Expert review of stillborn cases demonstrated a stillbirth misclassification rate of 33.3% during Helping Babies Breathe versus 5.9% in heart rate-guided resuscitation.…”

Dramatic Enhancement of Rare-Earth Metal–Organic Framework Stability Via Metal Cluster Fluorination by Matthew S. Christian (5101319)

“…The extent of fluorination in the metal clusters was validated through a ¹⁹F NMR characterization of 2,5-dihydroxyterepthalic acid (Y-DOBDC) MOF synthesized with a fluorine-containing modulator. …”

Image_10_Modulatory actions of Echinococcus granulosus antigen B on macrophage inflammatory activation.tif by Ana Maite Folle (3613004)

“…., one of these lipoproteins is antigen B (EgAgB), codified by a multigenic and polymorphic family that gives rise to five gene products (EgAgB8/1-5 subunits) assembled as a 230 kDa macromolecule. …”

Table_2_Sperm DNA Hypomethylation Proximal to Reproduction Pathway Genes in Maturing Elite Norwegian Red Bulls.XLSX by Abdolrahman Khezri (8055263)

“…Most of the identified DMRs (69%) exhibited a less than 10% methylation difference while only 1.5% of DMRs exceeded a 25% methylation difference. …”

Data Sheet 1_Modified life’s essential 8 mediate the correlation between dietary index for gut microbiota and sleep disorders.docx by Juanjuan Fang (413481)

“…Individuals whose DI-GM was 5 or above had a 34% decreased chance of sleep disorders compared to those with scores of 3 or less (OR: 0.66, 95% CI: 0.52–0.85), while DI-GM beneficial scores ≥6 reduced the risk by 35% compared to those with scores ≤1 (OR: 0.65, 95% CI: 0.49–0.85). …”

Data Sheet 3_Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.csv by Qingzhu Liang (22315633)

“…Gene expression was associated with immune cell infiltration: HCM samples showed increased CD4+ T cells and M0 macrophages but decreased M2 macrophages and neutrophils. The ceRNA network comprised 5 mRNAs, 40 miRNAs, and 152 lncRNAs. …”

Image_3_Upregulation of Extracellular Vesicles-Encapsulated miR-132 Released From Mesenchymal Stem Cells Attenuates Ischemic Neuronal Injury by Inhibiting Smad2/c-jun Pathway via A... by Bin Feng (108287)

“…<p>Ischemic cerebrovascular disease is a significant and common public health issue worldwide. …”

DataSheet_1_Terminal fucosylation of haptoglobin in cancer-derived exosomes during cholangiocarcinoma progression.pdf by Hyewon Choi (687527)

“…Mechanically, it is primarily due to β-haptoglobin (β-Hp) originating from CCA expressing fucosyltransferase-3/4 (FUT 3/4) and N-acetylglucosaminyltransferase-V (MGAT5). Newly synthesized β-Hp is loaded into EVs in early endosomes via a KFERQ-like motif and then secreted from CCA cells to induce tumor progression. …”

Data_Sheet_1_Sperm DNA Hypomethylation Proximal to Reproduction Pathway Genes in Maturing Elite Norwegian Red Bulls.DOCX by Abdolrahman Khezri (8055263)

“…Most of the identified DMRs (69%) exhibited a less than 10% methylation difference while only 1.5% of DMRs exceeded a 25% methylation difference. …”

Data Sheet 1_Unveiling causal immune cell–gene associations in multiple myeloma: insights from systematic reviews and Mendelian randomization analyses.docx by Hui Zhang (7197)

“…Post-adjustment for multiple testing, the levels of seven types of immune cells (two types of Treg, two types of TNBK, two types of B cells, and one type of Myeloid cell) were found to be elevated in association with an increased risk of multiple myeloma (MM), while the levels of another eight types of immune cells (one types of Treg, three types of TNBK, one type of MT cells, and two types of Myeloid cell and one type of cDC cells) were demonstrated to be associated with a decreased risk of MM. As supported by sensitivity analysis. …”

Data Sheet 3_The novel pleuromutilin derivative 22–((4-((4-nitrophenyl)acetamido)phenyl)thio)deoxy pleuromutilin possesses robust anti-mycoplasma activity both in vitro and in vivo... by Xirui Xia (12075476)

“…</p>Results<p>The results show that compound 16C has low toxicity (LD₅₀ > 5,000 mg/kg). Its pharmacokinetic profile is characterized by a short time to maximum concentration (Tmax = 0.24 h), high bioavailability (F = 71.29%), and short elimination half-life (T_1/2kel) (intramuscular and intravenous administration was 2.20 and 1.89 h, respectively). …”

DataSheet1_QiShenYiQi Pill Ameliorates Cardiac Fibrosis After Pressure Overload-Induced Cardiac Hypertrophy by Regulating FHL2 and the Macrophage RP S19/TGF-β1 Signaling Pathway.pd... by Gulinigaer Anwaier (6903299)

“…QSYQ also inhibited the following: release of RP S19 from the injured myocardium, activation of C5a receptors in monocytes, polarization of macrophages, and release of TGF-β1. …”

DataSheet_1_The changes in peripheral blood Th17 and Treg ratios in Hashimoto’s thyroiditis are accompanied by differential PD-1/PD-L1 expression.xlsx by Jun Fang (44152)

“…</p>Conclusion<p>(1) The increased percentage of Th17s and decreased percentage of PD-1⁺ Th17s in the HT group suggest that a loss of control on Th17 activity through the checkpoint inhibitory axis PD-1/PD-L1 may participate in disease pathogenesis. (2) While the decreased percentage of Tregs in HT patients may explain a lack of regulatory functions able to prevent the autoimmune destruction of the thyroid, the significance of the increased frequency of Tregs expressing PD-1 and PD-L1, previously reported to boost Tregs differentiation, remains to be established. …”