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113781
Image_1_Mitochondrial Function in Hereditary Spastic Paraplegia: Deficits in SPG7 but Not SPAST Patient-Derived Stem Cells.JPEG
Published 2020“…The mitochondrial dysfunction observed here in SPG7 patient cells that express paraplegin was similar to the dysfunction reported in cell models without paraplegin expression. The p.A510V mutation was common to all patients and was the likely species associated with increased expression, albeit seemingly non-functional. …”
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113782
Table_4_Reactive oxygen species-related genes participate in resistance to cucumber green mottle mosaic virus infection regulated by boron in Nicotiana benthamiana and watermelon.x...
Published 2022“…The similar results were obtained in watermelon by silencing of ClCat, ClPrx or ClGST expression using a pV190 vector. This study proposed a new strategy for improving plant resistance to CGMMV infection by boron-regulated ROS pathway and provided several target genes for watermelon disease resistance breeding.…”
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113783
Table_10_Reactive oxygen species-related genes participate in resistance to cucumber green mottle mosaic virus infection regulated by boron in Nicotiana benthamiana and watermelon....
Published 2022“…The similar results were obtained in watermelon by silencing of ClCat, ClPrx or ClGST expression using a pV190 vector. This study proposed a new strategy for improving plant resistance to CGMMV infection by boron-regulated ROS pathway and provided several target genes for watermelon disease resistance breeding.…”
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113784
Image_1_Ginseng-derived nanoparticles inhibit lung cancer cell epithelial mesenchymal transition by repressing pentose phosphate pathway activity.tif
Published 2022“…The results indicated that GDNPs most significantly inhibited proliferation and migration of lung cancer-derived tumor cells (A549, NCI-H1299). Moreover, GDNPs treatment also inhibited cell migration, invasion, clonal formation, and adhesion tube formation ability and reduced expression of EMT-related markers in A549 and NCI-H1299 cells in a dose-dependent manner. …”
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113785
In vitro efficacy of two commercial products of Metarhizium anisopliae s.l. for controlling the cattle tick Rhipicephalus microplus
Published 2021“…Three concentrations (108, 107, and 106 conidia mL-1) for both products were prepared in water + 0.1% Tween® 80 (v/v); afterward, bioassays were carried out for all R. microplus stages by immersion in suspensions (Metarril® SP) or formulations (Metarril® SC). …”
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113786
Molecular Properties Determining Unbound Intracellular and Extracellular Brain Exposure of CNS Drug Candidates
Published 2015“…Interpretable molecular descriptors that significantly contribute to the three key neuropharmacokinetic properties related to BBB drug transport (<i>K</i><sub>p,uu,brain</sub>), intracellular accumulation (<i>K</i><sub>p,uu,cell</sub>), and binding and distribution in the brain (<i>V</i><sub>u,brain</sub>) for a set of 40 compounds were identified using partial least-squares (PLS) analysis. …”
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113787
Physical-chemical properties of meat from confined lambs with different levels of cottonseed in the diet
Published 2021“…<div><p>ABSTRACT The aim of this study was to evaluate the effect of different levels of cottonseed (0, 100, 200, 300 and 400 g Kg-1) on the physical and chemical parameters of the meat of finishing lambs. Forty-five uncastrated male lambs were distributed in a completely randomised design with five treatments of nine replications. …”
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113788
Chemical and Enzymatic Probing of the SoSLIP and Its Resulting Secondary Structure in the Presence and in the Absence of FMRP
Published 2009“…<div><p>(A) PAGE gel showing the running of retrotranscribed SoSLIP RNA after treatment with RNase V1 (left), DMS (middle), and lead (right). …”
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113789
Image 1_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
Published 2025“…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …”
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113790
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113791
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113792
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113793
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113794
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113795
Image 2_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
Published 2025“…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …”
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113796
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113797
Image 3_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
Published 2025“…When both mitochondrial fractions were exposed to increasing mCa<sup>2+</sup> loads we observed decreased mCa<sup>2+</sup> sequestration in synaptic mitochondria as assessed by a significant increase in the steady-state free extra matrix Ca<sup>2+</sup> (ss[Ca<sup>2+</sup>]<sub>e</sub>) compared to non-synaptic mitochondria. …”
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113798
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113799
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113800