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Decreased vagal activity and deviation in sympathetic activity precedes development of diabetes
Published 2020“…In Cox analysis, as SDNN, RMSSD, and normalized HF tertiles increased, the risk of diabetes decreased [hazard ratios (95% confidence intervals) of tertile 3: 0.81 (0.70-0.95), 0.76 (0.65-0.90) and 0.78 (0.67-0.91), respectively], whereas the risk of diabetes increased in the case of heart rate, normalized LF, and LF/HF ratio [hazard ratios (95% confidence intervals) of tertile 3: 1.41 (1.21-1.65), 1.32 (1.13-1.53), and 1.31 (1.13-1.53), respectively] after adjusting for age, sex, body mass index, smoking, drinking, systolic blood pressure, lipid level, c-reactive protein, and homeostasis model assessment of insulin resistance.…”
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OCA alone markedly decreases and combined with Gemcitabine or Cisplatin abrogates growth of iCCA xenografts.
Published 2019“…After 4 weeks, when the tumor size was approximately 100 mm<sup>3</sup> (T<sub>0</sub>) mice were treated with OCA (0.03% w/w, 30 mg/kg) alone or combined with Cisplatin (2.4 mg/Kg in 100 μl) or Gemcitabine (1.05 mg/Kg in 100 μl) for 5 additional weeks. a) Results are expressed as percent increase in tumor volume at different time points. …”
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Wnt5a expressing tumors demonstrate a decrease in markers of the basal tumor subtype.
Published 2014“…MMTV-Wnt1;MMTV-Wnt5a tumors demonstrated a significant decrease in K6-expressing cells as measured by T-test (* = p<0.05).…”
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87
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Image_1_Loneliness predicts decreased physical activity in widowed but not married or unmarried individuals.TIF
Published 2024“…</p>Methods<p>We analyzed data from 1,931 older adults without dementia at baseline from the Rush Memory and Aging Project with a mean follow-up of 4.8 years (mean age 79.6 ± 7.7, 74.9% women). …”
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Image1_Decreased mitochondrial respiration associates with frailty in community-dwelling older adults.jpg
Published 2024“…Regarding the nutritional status defined as the body mass index, most non-frail individuals were normal or overweight, while frail participants were mostly overweight or obese. We observed that OCR was significantly decreased in frail men (p < 0.01). …”
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90
Decreased respiratory performance of children and adolescents with myelomeningocele who use a wheelchair – preliminary data
Published 2019“…MMC (n=10) and healthy (n=25) participants of both genders with a mean age of 12.45 years (SD=2.1) were assessed for weight, height, respiratory performance, and isometric peak for shoulder flexors, extensors, abductors, and adductors, using an isokinetic dynamometer. …”
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Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis
Published 2013“…The relative expression (2<sup>-ΔΔCt</sup> mean ± SEM) of hepatic CYP3A4 mRNA was significantly higher in cirrhotic livers (21.76 ± 2.65 vs. 5.91 ± 1.29, P=2.04E-07) but their levels did not significantly correlate with hepatic CYP3A activity (r=-0.43, P=0.08).…”
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Claudin V is decreased following infection with Mtb.
Published 2024“…<p>Immunofluorescent staining of guinea pig brain tissue for DAPI (blue) and claudin V (cyan) in vessels was performed. Representative images of the frontal cortex (A–D), cerebral nuclei (F–I), brain stem (K–N), thalamus (P–S), and hippocampus (U–X) 15 days post-infection are shown. …”
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