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81
miR-105 results in decreased Cdk6 expression at both the mRNA and protein levels.
Published 2013“…Blots were reprobed for levels of β-actin as a loading control for total protein. We observed a significant decrease in both Cdk6 mRNA and protein expression in miR-105 overexpressing as compared to control mimic-transfected PC3 cells. …”
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C2GnT1 gene knockdown decreases C2-O-sLe<sup>X</sup> glycoproteins and C2GnT1 activity.
Published 2013“…Note the absence of a detected C2GnT1 protein 50 kDa band. (D) We observed a 30–40% decrease in reactivity with CHO-131 mAb by flow cytometry for LS174T and HepG2 cells that contained C2GnT1 shRNA. …”
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85
DataSheet_1_Decreased TCF1 and BCL11B expression predicts poor prognosis for patients with chronic lymphocytic leukemia.docx
Published 2022“…T cell factor 1 (TCF1, encoded by the TCF7 gene) can be used as a critical determinant of successful anti-tumor immunotherapy and a prognostic indicator in some solid tumors; however, the effects of TCF1 in CLL remain unclear. …”
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86
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<i>roh</i> mutation results in Rh1 decrease.
Published 2015“…<p>(A) GFP fluorescence of one-day old wild-type (left panel) and <i>roh</i><sup><i>EY04039</i></sup> (right panel) flies showing a reduction in Rh1-GFP. …”
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88
Proteasome activity was decreased in the <i>myc-rpt6-S119A</i> mutant.
Published 2017“…The mean ± SEM rate of Suc-LLVY-AMC cleavage is decreased in the <i>myc-rpt6-S119A</i> mutant compared to the WT and <i>myc-rpt6-S119D</i> strains. …”
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Presentation_1_Airway macrophages display decreased expression of receptors mediating and regulating scavenging in early cystic fibrosis lung disease.pdf
Published 2023“…Compared to matched blood monocytes, AMs had a higher expression of CD16, CD91, and PD-1, and a lower expression of CD163, SIRPα and CD36.…”
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92
<i>Kdm6a</i> conditional KO mice have decreased repopulating potential in serial competitive transplantation assays.
Published 2021“…Whole BM cells were harvested from all cohorts of young <i>Kdm6a</i> conditional KO mice (CD45.2) and mixed with WT competitor marrow (CD45.1 x CD45.2) in a 1:1 ratio, which was then transplanted into lethally-irradiated primary recipient mice (CD45.1). …”
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93
mTORC1 hyperactivation led to a decreased autophagic activity in the podocytes.
Published 2020“…<p>(<b>A</b>) Primary cultured podocytes were isolated from <i>Tsc2</i><sup>Δ<i>podocyte</i></sup> and wild-type controls, followed by western blot analyses of TSC2, phospho-4EBP1, LC3B type II, p62, phospho-ULK1, and β-tubulin. …”
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Factors associated with abnormal left ventricular ejection fraction (decreased or increased) in patients with sepsis in the intensive care unit
Published 2020“…<div><p>Background</p><p>Sepsis-induced cardiomyopathy (SIC) is known to show cardiac dysfunction in patients with sepsis. Both a decrease or an increase in ejection fraction (EF), an indicator of cardiac function, can occur. …”
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