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401
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402
Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2.
Published 2018“…In the case of D2HGDH protein, the mutations I147S and V444A that are positioned in the beta sheet region exhibited higher Root Mean Square Deviation (RMSD), decrease in compactness and number of intramolecular hydrogen bonds compared to the mutations N439D and D375Y that are positioned in the turn and loop region, respectively. …”
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403
Inter-annual variability and distribution of aerosols during winters and aerosol optical thickness over Northeastern Pakistan
Published 2020“…ir pollution during winters over north-eastern (NE) Pakistan (71–74.5 E, 28–34 N) is a major challenge that affects human health, climate and daily life. …”
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404
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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405
Alveolar bone changes following bi-maxillary vertical molars' movements using clear aligners
Published 2023“…Result The patients were divided into two groups: extrusion (48.9%, n = 65 molars’ root) and intrusion (51.1%, n = 68 molars’ root) group. …”
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406
AMPK Activation Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro
Published 2016“…Similarly, the phosphorylation of AKT and P70S6K (a downstream target of mTOR) was increased by more than 1.5-fold in cells subjected to albumin treatment. …”
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407
Correlation between delta-endotoxin and proteolytic activities produced by Bacillus thuringiensis var. kurstaki growing in an economic production medium
Published 2013“…Maximal protease activity (540-2468 UI) obtained by BUPM5-1 and BUPM5-2 was 2.34-fold and 10.7-fold, respectively, more than that obtained by the wild strain BUPM5 with a drastic decrease of their delta-endotoxin production. …”
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408
Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma
Published 2016“…Results: hour annonacin treatment caused a significant and dose-dependent decrease in the viability of CaKi-2 cells, i.e., 42% in 0.5 ?…”
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409
Effect of Magnetic Baffles and Magnetic Nanofluid on Thermo-Hydraulic Characteristics of Dimple Mini Channel for Thermal Energy Applications
Published 2022“…The increment changed to 1.82%, 8.16%, and 22.31% for a pitch = 5 mm and 1.01%, 5.96%, and 21.38% for a pitch = 2.5 mm. …”
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410
Thermoelectric properties of SbNCa3 and BiNCa3 for thermoelectric devices and alternative energy applications
Published 2014“…The maximum values of thermal conductivity are 92×1014 W/m K s and 88×1014 W/m K s for SbNCa3 and BiNCa3 respectively at a temperature of 900 K. The peak values of 5×1020/Ω m s and 5.2×1020/Ω m s are achieved for n-type SbNCa3 and BiNCa3 respectively at a temperature of 300 K. …”
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411
Effect of hyperglycemia on EPCs function and regenerative ability
Published 2020“…For that, we studied BOECs viability, response to shear stress, angiogenesis ability, and barrier function under normoglycemic (5.5mM) and hyperglycemic (25mM) conditions. The results have shown significant effects of chronic hyperglycemic conditions on cell proliferation (n=3, p<0.05), and migration (n=3, p<0.05) which were decreased when compared to control. …”
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412
Epidemiology of herpes simplex virus type 2 in Europe: systematic review, meta-analyses, and meta-regressions
Published 2023“…HSV-2 detection in genital herpes cases was 1.21-fold (95% CI: 1.10–1.32) higher in men compared to women and decreased by 1% per calendar year. …”
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413
Pilot-scale petroleum refinery wastewaters treatment systems: performance and microbial communities' analysis
Published 2020“…Decreasing HRT to 5 and 2.5 days led to a decrease in the efficiency of the process and a decrease in biomass concentration was also observed (<1000 mg/l). …”
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414
The Cellular Interplay Between Na+/H+ Exchanger Isoform I and Osteopontin in Cardiac Hypertrophy
Published 2014“…This was significantly abolished in the presence of siRNA-OPN (20.2 fold decrease±0.12 of control) and (68.5±0.24% vs. 586.5±103.54% NHE1-infected). …”
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415
Impact of combined oil-in-water emulsions and particulate suspensions on ceramic membrane fouling and permeability recovery
Published 2019“…The addition of 1500 mg·L−1 of bentonite to a 10 vol.% emulsion resulted in a permeability decrease of 3.5–5 times over that recorded for the emulsion, and 8–36 times lower than that of the bentonite suspension. …”
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416
Radiofrequency Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation: Meta-analysis of Safety and Efficacy
Published 2019“…BACKGROUND: Radiofrequency ablation (RFA) and antiarrhythmic drugs (AADs) are the main treatments used for atrial fibrillation (AF). In recent years, a number of articles comparing the 2 treatments have begun to emerge. …”
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417
EPIDEMIOLOGY OF CHLAMYDIA TRACHOMATIS IN LATIN AMERICA AND THE CARIBBEAN: SYSTEMATIC REVIEW, META-ANALYSES, AND META-REGRESSIONS
Published 2022“…We conducted random-effects meta-regressions to identify sources of heterogeneity and possible predictors of high prevalence. Results: The pooled-mean urogenital CT prevalence was 8.2% (95% CI: 7.5-9.1) for general populations, 14.0% (95%CI: 12.7-15.4) for female sex workers, 10.8% (95% CI: 8.4-13.4) for men who have sex with men, male sex workers, and transgenders, 16.1% (95% CI: 12.6-19.8) for symptomatic women, 25.4 (95% CI: 18.6-38.5) for symptomatic men, 9.7% (95%CI: 6.1-14) for HIV-positive individuals and individuals in HIV-discordant couples, and 11.9% (95 CI: 8.5-15.8) for STI clinic attendees. …”
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418
Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus
Published 2023“…They have demonstrated1 that empagliflozin treatment resulted in a significant decrease in pulse pressure (PP), mean arterial pressure (MAP) and cardiac workload, compared with placebo; at week 12, placebo-adjusted mean changes from baseline were − 2.5 mmHg for PP, − 2.2 mmHg for MAP and − 315 mmHg x beats per minute (bpm) for cardiac workload (p < 0.0001 for all). …”
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419
Prevalence of vincristine induced-peripheral neuropathy among Sudanese cancer patients
Published 2016“…Majority of the patients (n=37, 47.5%) showed mild paresthesia as graded by the 'WHO grading scale'. …”
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420
Specific Bioactive Compounds from Ginger, Tea, and Apple Prevent Diabetes-Related Cataract Via Inhibition of Aldose Reducatse
Published 2016“…The activity of aldose reductase was found to increase 5 folds at 10 mM from day 1 to day 4, whereas at 25, 50 and 100 mM concentrations of glucose the AR activity was increased to almost 2 folds. …”
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