Nanosized Hybrid Oligoamide Foldamers: Aromatic Templates for the Folding of Multiple Aliphatic Units by David Sánchez-García (1608835)

“…For example, a 40mer with a sequence (PQ₄)₈ folds into a rod-like helix spanning over 16 turns with a length of 5.6 nm. …”

Nanosized Hybrid Oligoamide Foldamers: Aromatic Templates for the Folding of Multiple Aliphatic Units by David Sánchez-García (1608835)

“…For example, a 40mer with a sequence (PQ₄)₈ folds into a rod-like helix spanning over 16 turns with a length of 5.6 nm. …”

Nanosized Hybrid Oligoamide Foldamers: Aromatic Templates for the Folding of Multiple Aliphatic Units by David Sánchez-García (1608835)

“…For example, a 40mer with a sequence (PQ₄)₈ folds into a rod-like helix spanning over 16 turns with a length of 5.6 nm. …”

CD148 knockdown reduces cell-cell adhesion and E-cadherin contacts accompanied by a decrease in Rac1 activity in A431 cells. by Keiko Takahashi (375228)

“…CD148 knockdown reduces the E-cadherin contact formation accompanied by a decrease in Rac1 activity.</p>…”

Upregulation of miR-30a-5p resulted in promotion of glioblastoma cell growth that was reversed partially by Ad-S7. by Zhifan Jia (286723)

“…<p>(A) The figure showed that 30a-5p m increased the cell survival rate at a significantly higher rate in SNB19 cells and LN229 cells, (B) accelerated the glioma cells from G0/G1 to S phase in SNB19 cells and LN229 cells, (C) decreased the apoptotic cells in the 30a-5p m group, (D) promoted the cell invasive ability. …”

Data_Sheet_1_Microclimatic Warming Leads to a Decrease in Species and Growth Form Diversity: Insights From a Tropical Alpine Grassland.PDF by Sisimac A. Duchicela (11503918)

“…The increase of tussocks led to a significant decrease in species diversity and evenness inside OTCs, but not in species richness after accounting by sampling time. …”

Lipid profile is associated with decreased fatigue in individuals with progressive multiple sclerosis following a diet-based intervention: Results from a pilot study by Kelly Fellows Maxwell (6852752)

“…</p><p>Results</p><p>FSS scores decreased from a baseline of 5.51 (95% CI: 4.86, 6.16) to a mean of 3.03 (95% CI: 2.23, 3.82) at 12 months (p < 0.001). …”

VEGFa, VEGFR1 and VEGFR2 mRNA levels following A2E incubation and/or light exposure. by Mélanie Marie (7535228)

HDACi-resistant HCT-R cells exhibit high expression levels of pAKT, a downstream effector of WNT5A and ROR2. by Michael Bordonaro (340595)

“…Cells were exposed to 1.5 mM 5-FU for 24 hrs, and apoptotic assays were performed as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0027308#s4" target="_blank">Materials and Methods</a>. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

table_1_A Beneficial Effect of Low-Dose Aspirin in a Murine Model of Active Tuberculosis.docx by Vera Marie Kroesen (5128211)

“…Results from the immunological studies suggest the anti-inflammatory action of LDA at both a local and a systemic level. Our results showed a systemic decrease in neutrophilic recruitment, decreased levels of acute-phase reaction cytokines (IL-6, IL-1β, and TNF-α) at late stage and a delay in the decrease in T cell response (in terms of IFN-γ, IL-2, and IL-10 serum levels) that occurs during the course of Mycobacterium tuberculosis infection. …”

Hydrogen volume fraction distribution at different pressures (a) 1 MPa; (b) 3 MPa; (c) 5 MPa. by Weiqing Xu (1279959)

Ctcf and Smarca5 interact in AML cells. by Martina Dluhosova (519144)

“…D Smarca5 at ICR upon Ctcf knockdown. Occupancy of Smarca5 (lysates from 1A) by ChIP. …”

C5aR1 Mediates the Progression of Inflammatory Responses in the Brain of Rats in the Early Stage after Ischemia and Reperfusion by Yunwei Shi (10116568)

“…Further mechanism studies showed that inhibiting C5aR1 by PMX53 protected the rats from MCAO/R injury, decreased cell inflammation, and apoptosis via inhibiting the TLR4 and NF-κB signaling pathway and reducing the production of TNF-α, IL-1β, and IL-6 in MCAO/R rats. …”

C5aR1 Mediates the Progression of Inflammatory Responses in the Brain of Rats in the Early Stage after Ischemia and Reperfusion by Yunwei Shi (10116568)

“…Further mechanism studies showed that inhibiting C5aR1 by PMX53 protected the rats from MCAO/R injury, decreased cell inflammation, and apoptosis via inhibiting the TLR4 and NF-κB signaling pathway and reducing the production of TNF-α, IL-1β, and IL-6 in MCAO/R rats. …”

C5aR1 Mediates the Progression of Inflammatory Responses in the Brain of Rats in the Early Stage after Ischemia and Reperfusion by Yunwei Shi (10116568)

“…Further mechanism studies showed that inhibiting C5aR1 by PMX53 protected the rats from MCAO/R injury, decreased cell inflammation, and apoptosis via inhibiting the TLR4 and NF-κB signaling pathway and reducing the production of TNF-α, IL-1β, and IL-6 in MCAO/R rats. …”

C5aR1 Mediates the Progression of Inflammatory Responses in the Brain of Rats in the Early Stage after Ischemia and Reperfusion by Yunwei Shi (10116568)

“…Further mechanism studies showed that inhibiting C5aR1 by PMX53 protected the rats from MCAO/R injury, decreased cell inflammation, and apoptosis via inhibiting the TLR4 and NF-κB signaling pathway and reducing the production of TNF-α, IL-1β, and IL-6 in MCAO/R rats. …”

C5aR1 Mediates the Progression of Inflammatory Responses in the Brain of Rats in the Early Stage after Ischemia and Reperfusion by Yunwei Shi (10116568)

“…Further mechanism studies showed that inhibiting C5aR1 by PMX53 protected the rats from MCAO/R injury, decreased cell inflammation, and apoptosis via inhibiting the TLR4 and NF-κB signaling pathway and reducing the production of TNF-α, IL-1β, and IL-6 in MCAO/R rats. …”

Best predictors of income derived from forest, husbandry, off-farm, Amazon nut and timber. by Marlene Soriano (582736)