Targeted point mutation (F639A) in the GluN1 subunit decreases ethanol sensitivity of NMDA receptors. by Carolina R. den Hartog (484817)

OCA alone markedly decreases and combined with Gemcitabine or Cisplatin abrogates growth of iCCA xenografts. by S. Di Matteo (6260417)

“…After 4 weeks, when the tumor size was approximately 100 mm³ (T₀) mice were treated with OCA (0.03% w/w, 30 mg/kg) alone or combined with Cisplatin (2.4 mg/Kg in 100 μl) or Gemcitabine (1.05 mg/Kg in 100 μl) for 5 additional weeks. a) Results are expressed as percent increase in tumor volume at different time points. …”

Mitochondrial dysfunction is driven by decreased mitochondrial dynamics. by Piero Dalle Pezze (622889)

“…Scale bar represents the normalised positive or negative sensitivity of each species to each rate constant. (B) <i>In silico</i> time courses over 21 days post-irradiation for the two states of mitochondrial mass (new and old) were computed by separately perturbing the previous kinetic rates by different factors f (f = 1 is the control). …”

ZEBRA and BGLF5 decrease levels of GFP mRNA and protein; one point mutant of ZEBRA does not inhibit GFP expression. by Richard Park (547667)

PowerPoint Slides for: Patiromer Decreases Serum Potassium and Phosphate Levels in Patients on Hemodialysis by Bushinsky D.A. (3246690)

“…<p><b><i>Background:</i></b> Persistent hyperkalemia (serum potassium (K) ≥5.5 mEq/l) is a common condition in hemodialysis (HD) patients, is associated with increased mortality, and treatment options are limited. …”

Data_Sheet_1_The Risky Decrease of Fishing Reference Points Under Climate Change.docx by Morgane Travers-Trolet (548023)

“…The model was first parameterized and run to fit the historical situation (2000–2009) and then used to assess the ecosystem state for the 2050–2059 period, using two contrasting climate change scenarios (RCP 4.5 and RCP 8.5). For each condition, a monospecific MSY estimation routine was performed by varying species fishing mortality independently and allowed estimation of reference points for each species. …”

Increases in 1,5-anhydrosorbitol and decreases in ascorbic acid following RYGB. by David M. Mutch (37665)

“…B) For ascorbic acid, the ANOVA model did not detect group-specific changes over time (no group:time interaction), but indicated significant decreases from T0 to T6 in both groups. Overall, 1,5-anhydrosorbitol and ascorbic acid were significantly different at each time point between OB and OB/D subgroups (p<0.01, see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007905#pone-0007905-t002" target="_blank"><b>TABLE 2</b></a>).…”

DataSheet1_A Non-Synonymous Point Mutation in a WD-40 Domain Repeat of EML5 Leads to Decreased Bovine Sperm Quality and Fertility.docx by Eriklis Nogueira (7475576)

Resveratrol decreased tumor latency in <i>Sirt1^Y/+</i> mice. by Katherine V. Clark-Knowles (368164)

Homozygous deletion of <i>ERG251</i> leads to the decreased ergosterol accumulation in the absence of FLC and decreased production of toxic dienol in the presence of FLC. by Xin Zhou (54275)

Loss of FOXP1 results in decreased number of bRGCs. by Seon Hye E. Park (16765033)

LMP1 decreases mitochondrial respiration. by Michael Hulse (5932112)

MK-STYX decreases RhoA activation. by Brittany M. Flowers (670483)

“…<p>(<b>A</b>) PC12 cells were transfected with pMT2 or pMT2-FLAG-MK-STYX-FLAG. 24 hr post-transfection cells were stimulated with 100 ng/ml NGF, and lysed at the indicated time points. …”

28 days of testosterone depletion decreases fiber CSA only in the TA muscle and only at 1.5-month-old mice. by Arik Davidyan (10450896)

Stat1 activation is strongly decreased by MNV-S99 infection. by Sandra Niendorf (2832785)

PB + PER exposure decreased SYP staining in the hippocampi and cerebral cortices of exposed mice. by Zuchra Zakirova (431614)

Stroma decreases spheroid size by decreasing cell width. by Karen F. Chambers (224337)

High fat diet decreased tumor latency but did not affect survival in MMTV-PyMT transgenic mice. by Katherine V. Clark-Knowles (368164)

TRIM5 restriction of HIV-1 has decreased during evolution leading to humans. by Michael Emerman (12304)

“…Original data is found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000301#pbio.1000301-Goldschmidt1" target="_blank">[30]</a> and shows that the antiviral gene TRIM5 restricted HIV-1 better at points in evolution earlier than the chimp–human common ancestor than it does after that. …”

Rank importance, where impairment at a point has a significant association with decreased vision-related quality of life. by Hiroshi Murata (387321)