Image_1_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”

Image_2_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”

Comparison of WT and mutant SHC014-CoV S ectodomains. by Alexandra L. Tse (20235212)

“…Area under the curve represents protein expression. A835D-containing variants exhibit a large decrease in protein expression relative to the WT and F294L SHC014-CoV spikes. …”

Propensity-score matched open aortic group. by Tomi Obafemi (12328433)

“…Patients who underwent open aortic procedures experienced an improvement in 30-day mortality (7% to 3.5%, p = 0.012), decrease in median ICU LOS (91.7 hours to 69.6 hours, p<0.001), and a decrease in duration of mechanical ventilation (79.3 hours to 46.3 hours, p = 0.003). …”

Pre-match open aortic group. by Tomi Obafemi (12328433)

“…Patients who underwent open aortic procedures experienced an improvement in 30-day mortality (7% to 3.5%, p = 0.012), decrease in median ICU LOS (91.7 hours to 69.6 hours, p<0.001), and a decrease in duration of mechanical ventilation (79.3 hours to 46.3 hours, p = 0.003). …”

Pre-match CABG/Valve group. by Tomi Obafemi (12328433)

“…Patients who underwent open aortic procedures experienced an improvement in 30-day mortality (7% to 3.5%, p = 0.012), decrease in median ICU LOS (91.7 hours to 69.6 hours, p<0.001), and a decrease in duration of mechanical ventilation (79.3 hours to 46.3 hours, p = 0.003). …”

Propensity-score matched CABG/Valve group. by Tomi Obafemi (12328433)

“…Patients who underwent open aortic procedures experienced an improvement in 30-day mortality (7% to 3.5%, p = 0.012), decrease in median ICU LOS (91.7 hours to 69.6 hours, p<0.001), and a decrease in duration of mechanical ventilation (79.3 hours to 46.3 hours, p = 0.003). …”

Fig 5 - by Koji Kashihara (12475877)

The variation curve of the energy density at the peak point with different freezing temperature. by Liang Zhang (41392)

(A) The proportion of fast MyHC myotubes is decreased in Igf-2 deficient mice (maternal disomy Chromosome 7 - MatDi) at E14 by Deborah Merrick (54928)

“…(B) Embryo immunoblotting for Igf-2 demonstrates a stage related increase in Igf-2 protein between E10.5 and E15.5 in WT and absence of Igf-2 in MatDi embryos at E14.5 and E15.5 Tracks 1–4 E10.5, E13.5, E14.5 and E15.5 WT embryos respectively, Track 5 E14.5 MatDi, Track 6 E15.5 MatDi and Track 7 E15.5 WT. …”

Tie2 and Vav-iCre mediated deletion of Zeb1 leads to sub-mendelian rates of transmission at weaning but no signs of embryonic lethality. by Jueqiong Wang (11467505)

Enhanced Nrf2 activity decreases lipid clearance rate and VLDL secretion in Keap1-KD mice. by Jialin Xu (40952)

HENMT1 loss results in decreased piRNA bulk and the absence of 3’ 2’-O-methylation and stability. by Shu Ly Lim (578590)

Decrease of galectin-3 positive cells in bleomycin-injured lung tissue upon administration of hUC-MSC. by Gianluca Moroncini (784833)

“…Lung sections obtained from C57BL/6 mice (n = 8 per group) were immunostained with anti-galectin-3 antibody. At each time point, the number of immunoreactive macrophages infiltrating the lungs are significantly decreased by hUC-MSC infusion in comparison to bleomycin-treated mice. …”

The inflammatory process resulting from TIN is decreased in TLR 2, -4, and MyD88 KO mice. by Matheus Correa-Costa (119464)

Peripheral Erythrocytes Decrease upon Specific Respiratory Challenge with Grass Pollen Allergen in Sensitized Mice and in Human Subjects by Galateja Jordakieva (512458)

“…A significant decrease in circulating erythrocytes and hematocrit levels after airway challenges with grass pollen allergen was also found in grass pollen sensitized human rhinitis subjects (n = 42) at the VCC. …”

Mutations in the QseE N-terminus impairing interaction with QseG concomitantly decrease QseE activity. by Yvonne Göpel (5549291)

<i>Furin</i> mutant hearts show a decreased in the number of phospo-Smad positive cells at the AV junction. by Laurent Dupays (2940330)

Decreased LysoTracker-positive vacuoles containing <i>S. aureus</i> in <i>PRIP</i>-DKO MEFs. by Kae Harada-Hada (568788)

Neutrophil recruitment into the infected mucosa is decreased in absence of IL-18 but neutrophil depletion does not seem to be a main driver during the initiation of mucosal inflamm... by Anna A. Müller (2853470)