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point decrease » point increase (Expand Search)
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The 2lox Lsd1 variant shows decreased binding to known interactors.
Published 2013“…Data represent the mean +/− SD for two independent experiments. (C) Purification of endogenous Lsd1 complexes from MEF lines confirmed a decrease in Lsd1-CoREST interaction in cells expressing the mutant Lsd1. …”
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Deletion of STX1B decreases the size of RRP in glutamatergic and GABAergic synapses.
Published 2014“…Mean RRP size estimated from integral charge transfer induced by application of 0.5 M sucrose solution (right; WT, 2.27±0.17 nC, <i>n</i> = 88; STX1B<sup>−/−</sup>, 1.39±0.14 nC, <i>n</i> = 62; <i>p</i><0.001, two sample <i>t</i>-test). …”
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HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching.
Published 2015“…However, transfection of SUZ12 siRNA significantly reduced endothelial branching compared to HG+control siRNA. [NG+control siRNA = 5mM D-glucose + 100nM control siRNA, HG+control siRNA = 25mM D-glucose + 100nM control siRNA, HG+EZH2 siRNA = 25mM D-glucose + 100nM EZH2 siRNA, HG+SUZ12 siRNA = 25mM + 100nM SUZ12 siRNA; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to U6 or β-actin and expressed as a fold change of NG+control siRNA].…”
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Macroscopic and histological assessment of colic tumor and inflammation in mice.
Published 2020Subjects: -
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Decreased biomechanical stability of bones from <i>Col1a1-Krm2</i> transgenic mice.
Published 2013“…(D) Cortical thickness (C.Th.) and bone mineral density (vBMD) are decreased in <i>Col1a1-Krm2</i> transgenic mice compared to wildtype littermates. …”
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