A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation... حسب Thirumal Kumar, D

"…The molecular interaction study also revealed that the co-crystallized AKT1 inhibitor N-(4-(5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)-3H-imidazo [4,5-b]pyridin-3-yl)benzyl)-3-fluorobenzamide (12j) exhibited a better interaction with native AKT1 compared with the E17K mutant AKT1 protein, whereas, Akti-1/2 exhibited the opposite effects, i.e., a better interaction with the E17K mutant AKT1 than the native AKT1. …"
احصل على النص الكامل
احصل على النص الكامل

Effect of BPA on CYP450s expression, and nicotine modulation, in fetal rat brain حسب Mohammad H., Merii

"…Fetal brains were isolated at gestational days GD14 and GD19, and protein expression was assessed by Western blotting. Results showed a BPA-induced significant decrease in CYP1B1 expression levels at GD14 (p = 0.001), and CYP19A1 (aromatase) expression at both mid- and late-stage development (p < 0.001). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Genotoxic impact of long-term cigarette and waterpipe smoking on DNA damage and oxidative stress in healthy subjects حسب Alsaad A.M.

"…This was associated with a marked decrease (50%) in the expression of detoxifying genes (NQO1 and GSTA1) with an increase in CYP1A1 mRNA expression, a cancer-activating gene. …"
احصل على النص الكامل
احصل على النص الكامل

Coral reef resilience differs among islands within the Gulf of Mannar, southeast India, following successive coral bleaching events حسب Raj, K. Diraviya

"…Overall, between 2005 and 2017 reefs had a simultaneous decrease in relative coral cover (avg. = ? …"
احصل على النص الكامل
احصل على النص الكامل

MOLECULAR FEATURES OF TRIPLE NEGATIVE BREAST CANCER STEM CELLS: A GENE EXPRESSION PROFILING ANALYSIS OF MDA-MB-231 CELLS حسب Hourani, Shireen Bayan

"…Triple negative breast cancer (TNBC) is a chemoresistant subtype of female breast tumors. …"
احصل على النص الكامل

In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway حسب Kuttikrishnan, Shilpa

احصل على النص الكامل
احصل على النص الكامل

A novel index based on planktonic copepod reproductive traits as a tool for marine ecotoxicology studies حسب Mohamed Bakr, Hussain

"…At high concentrations, cadmium and silver induce an increase in EPR in the copepods Acartia tonsa and Acartia hudsonica, while exposure to mercury decreases EPR in adults by 50%. All three metals affect HS, with mercury inducing a stronger effect than cadmium and silver. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit حسب Al-Sulaiti, Fatima Khalifa

"…Objective: This study aimed to evaluate the appropriateness of gentamicin therapeutic drug monitoring (TDM) at a tertiary care hospital in Qatar. Methods: A one-year quantitative retrospective chart review of all gentamicin TDM records was conducted. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Advanced Hard Ctings: Towards A Whole New World حسب Santecchia, Eleonora

احصل على النص الكامل
احصل على النص الكامل

A Study Of Atmospheric Transparency Over Qena In Upper Egypt حسب El Shazly, S. M. [سيد محمد الشاذلي]

احصل على النص الكامل

Elaeagnus Angustifolia: a Promising Medicinal Plant for Cancer Theraby حسب Mohamed, Islam

احصل على النص الكامل
احصل على النص الكامل

Enhanced boron removal by electricity generation in a microbial fuel cell حسب Ping, Qingyun

"…Two scenarios were examined, the MFC as a pretreatment process and the MFC as a post-treatment step in connection with conventional desalination. …"
احصل على النص الكامل
احصل على النص الكامل

Qatar University culture collection: A source of biodiversity and numerous applications حسب Al Ghazal, Ghamza

احصل على النص الكامل
احصل على النص الكامل

A Multi-echelon Network Distribution Model For Emergency Resource Planning حسب Pradhananga, Rojee

احصل على النص الكامل
احصل على النص الكامل

A Reconfigurable Multipurpose SoC Mobile Platform for metal detection حسب Al Rshid Abazeed, Omran

احصل على النص الكامل
احصل على النص الكامل

A disease-modifying treatment for Alzheimer's disease: Focus on the trans-sulfuration pathway حسب Berry, Thomas

احصل على النص الكامل
احصل على النص الكامل

The impact of COVID-19 pandemic on tobacco use: A population-based study حسب Alomari, Mahmoud A.

"…Conclusions Changes in the SH during COVID-19 have been reported in about 50% of participants who smoke tobacco, with a more reported decrease than increase in use. …"
احصل على النص الكامل
احصل على النص الكامل

Implementing and Analyzing a Recursive Technique for Building Path Oblivious RAM حسب Rachid, Maan Haj

احصل على النص الكامل
احصل على النص الكامل