Image_4_Novel mediator in anaphylaxis: decreased levels of miR-375-3p in serum and within extracellular vesicles of patients.jpeg by Emilio Nuñez-Borque (17301673)

“…Extracellular vesicles (EVs) were characterized by Western blot, electron microscopy and NanoSight. A decrease of miR-375-3p levels was determined by qPCR in both serum and EVs of patients with anaphylaxis (****p<.0001). …”

Image_3_Novel mediator in anaphylaxis: decreased levels of miR-375-3p in serum and within extracellular vesicles of patients.jpeg by Emilio Nuñez-Borque (17301673)

“…Extracellular vesicles (EVs) were characterized by Western blot, electron microscopy and NanoSight. A decrease of miR-375-3p levels was determined by qPCR in both serum and EVs of patients with anaphylaxis (****p<.0001). …”

Aquaporin-2 protein and mRNA expression in homogenates of the renal outer medulla. by Lucas H. Oronel (8525697)

Naïve CD8⁺ but not CD4⁺ T cells were significantly decreased in the periphery of Tsc1 KO mice. by Lianjun Zhang (181973)

“…<p>The peripheral T cell subsets of WT and Tsc1 KO mice were detected using FCM 4–5 wks after birth. <b>A.</b> Total thymic cell number and thymocyte subset profile of Tsc1 KO mice were identical as WT littermates. …”

RNA sequencing linkage analysis identifies a single base pair change on Chromosome 25 that is tightly linked to the <i>escapist</i> hypersensitive phenotype. by Elelbin A. Ortiz (8655285)

Shedding of PrP is decreased in PrP^CGPIThy-1 L150 mice but increases after RML infection. by Berta Puig (344828)

“…<p>(A) Representative western blot showing shed PrP (detected with our new antibody described in [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1007520#ppat.1007520.ref036" target="_blank">36</a>]) and total PrP levels (detected with POM1). …”

Survivability is decreased in zebrafish embryos following exogenous treatment with an amino-terminal fragment of nApoE4_1-151. by Madyson M. McCarthy (9238322)

Respiration patterns of <i>Pseudomonas</i> sp DR 5–09 when compounds were provided as sole nutrient sources or enriched with sodium succinate and ferric citrate. by Samareh Gharaie (4710206)

“…Grey and red links show compounds with non- significant and significant differences, respectively, when offered as a sole or enriched compound. Yellow links show compounds that decreased respiratory activity when offered as enriched compound compared with sole nutrient source. …”

Cluster 5—Gene Ontology. by Janaina de Freitas Nascimento (3849415)

“…Furthermore, metacyclics with Pro-Ile and Pro-Val exhibited elevated enzymes linked to lipid and redox metabolism. The results revealed five proteins that were increased and four that were decreased in common in the presence of Pro+BCAAs, indicating their possible participation in key processes related to metacyclogenesis. …”

Population dynamics of <i>Killer-Rescue</i>/Cargo, <i>ClvR</i> and split^50cM <i>ClvR</i> V2. by Georg Oberhofer (3401438)

NatB inactivation decreased the level of MAPK and proposed model of EGFR/MAPK signaling regulation by NatB and the N-end rule pathways. by Zhentao Sheng (107495)

“…<p>(A-B) <i>psid-D1</i> (A) or <i>psid-D4</i> (B) clones in 3rd instar fat body, which were marked by GFP expression (pointed by arrowheads), showed decreased MAPK levels (anti-MAPK staining, red). …”

image_1_Complement Activation During Ischemia/Reperfusion Injury Induces Pericyte-to-Myofibroblast Transdifferentiation Regulating Peritubular Capillary Lumen Reduction Through pER... by Giuseppe Castellano (5258120)

“…Treatment by C1-inhibitor (C1-INH) significantly preserved the phenotype of pericytes maintaining microvascular density and capillary lumen area at tubulointerstitial level. In vitro, C5a transdifferentiated human pericytes in myofibroblasts, with increased αSMA expression in stress fibers, collagen I production, and decreased antifibrotic protein Id2. …”

image_2_Complement Activation During Ischemia/Reperfusion Injury Induces Pericyte-to-Myofibroblast Transdifferentiation Regulating Peritubular Capillary Lumen Reduction Through pER... by Giuseppe Castellano (5258120)

“…Treatment by C1-inhibitor (C1-INH) significantly preserved the phenotype of pericytes maintaining microvascular density and capillary lumen area at tubulointerstitial level. In vitro, C5a transdifferentiated human pericytes in myofibroblasts, with increased αSMA expression in stress fibers, collagen I production, and decreased antifibrotic protein Id2. …”

image_3_Complement Activation During Ischemia/Reperfusion Injury Induces Pericyte-to-Myofibroblast Transdifferentiation Regulating Peritubular Capillary Lumen Reduction Through pER... by Giuseppe Castellano (5258120)

“…Treatment by C1-inhibitor (C1-INH) significantly preserved the phenotype of pericytes maintaining microvascular density and capillary lumen area at tubulointerstitial level. In vitro, C5a transdifferentiated human pericytes in myofibroblasts, with increased αSMA expression in stress fibers, collagen I production, and decreased antifibrotic protein Id2. …”

image_4_Complement Activation During Ischemia/Reperfusion Injury Induces Pericyte-to-Myofibroblast Transdifferentiation Regulating Peritubular Capillary Lumen Reduction Through pER... by Giuseppe Castellano (5258120)

“…Treatment by C1-inhibitor (C1-INH) significantly preserved the phenotype of pericytes maintaining microvascular density and capillary lumen area at tubulointerstitial level. In vitro, C5a transdifferentiated human pericytes in myofibroblasts, with increased αSMA expression in stress fibers, collagen I production, and decreased antifibrotic protein Id2. …”

Constitutively nuclear Foxo1 reduced Na_V1.5 expression. by Weike Mao (181121)

“…<p>Western blots showed that overexpression of Foxo1-AA-GFP for 36 hours reduced Na_V1.5 protein level while it increased endogenous Foxo1 expression (A); quantitiation of Na_V1.5 protein level relative to GAPDH revealed that expression of Foxo1-AA-GFP (n = 5) significantly decreased (*p<0.05, at 10 MOI; **p<0.01 at 50 MOI) Na_V1.5 expression compared with 50 MOI GFP (n = 5) (C). …”

Decreases in time from AHP to threshold account for increased firing of cPLA₂α^-/- SCG neurons. by Liwang Liu (424650)

“…<p>(<b>A-B)</b> Examples of differences in AP firing during a 1 sec injection of 100 pA of current. …”

Sanger sequences for CRISPR generated <i>syt7a</i> mutant alleles. by Elelbin A. Ortiz (8655285)

Image_5_Epidemiological and Clinical Characteristics of Five Rare Pathological Subtypes of Hepatocellular Carcinoma.pdf by Xiaoyuan Chen (322516)

“…This study aimed to describe the epidemiological and clinical spectrum of five rare HCC subtypes and develop a competing risk nomogram for cancer-specific survival prediction.…”

Opportunistic analysis of clinically actionable DPYD gene variants in a germline testing cohort in India by Rajdeep Raha (22056304)

“…Comparative allele frequency analysis was performed using global population datasets to identify inter-population differences.</p> <p>A total of 95 individuals (5.3%) carried at least one decreased or no function DPYD variant, indicating a significant prevalence of clinically actionable genotypes in this Indian cohort. …”