GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) by F. Anthony Romero (2452198)

“…In pursuit of a more potent and selective CBP inhibitor, we used structure-based design. …”

Block-based RMSD analysis of the native protein-DNA complex. by Sneha P. (3926957)

Subjects:

Aged blood factors decrease cellular responses associated with delayed gingival wound repair by María Paz Saldías (4430032)

“…<div><p>Aging is a gradual biological process characterized by a decrease in cell and organism functions. …”

Data from: Spillage and food dust do not decrease efficacy of long-lasting insecticide-incorporated netting against stored product insects by Sabita Ranabhat (17484660)

Cost-effectiveness curves for the <i>R</i>_<i>w</i> and <i>I</i>_<i>w</i> under four BMP scenarios. by Runzhe Geng (5664928)

Cost-effectiveness curves for the <i>P</i>_<i>w</i> and <i>I</i>_<i>w</i> under four BMP scenarios. by Runzhe Geng (5664928)

Ppk1 levels are not affected by decreasing dendrite arbor size but are reduced when dendrite length increases. by Josephine W. Mitchell (17364781)

MEK5 expression decreases ER signaling and confers endocrine resistance. by James W. Antoon (444010)

Taste sensilla in the wing and RNA-seq screen of control and <i>Poxn</i> wings. by Zhe He (508742)

SRC-3 treatment decreased tumor growth in a Jeko-1 ibrutinib resistant mouse model. by Imani Bijou (18275174)

Near-infrared spectroscopy (NIRS)-obtained muscle oxygenation data at baseline, 50 W, and the ventilatory threshold (VT). by Austin K. Ederer (848527)

Hepatic Expression of Detoxification Enzymes Is Decreased in Human Obstructive Cholestasis Due to Gallstone Biliary Obstruction by Jin Chai (183630)

“…</p><p>Conclusions</p><p>The levels of hepatic detoxification enzymes were significantly decreased in human obstructive cholestasis, and these decreases were positively associated with a marked reduction of FXR levels. …”

TUDCA decreases ER stress in HOX neonatal rat lungs. by Kirkwood A. Pritchard Jr. (13449794)

“…(<b>C</b>) In IHC stain, P-IRE1α levels are decreased (40.8±3.5 A.U. <i>vs</i> 53.1±5.0 A.U., p<0.001, n = 6, 3 for each sex) in chronic hyperoxia exposed neonatal rat lungs by TUDCA. …”

Ofd1 protection of photoreceptors from oxidative stress via decreasing ROS production. by Juan Wang (115708)

“…MNU+Ofd1 CDS: after 661W transfected with pEGFP-Ofd1-CDS for 48h, MNU 500 ug/ml treated for 10 mins. …”

The three hit compounds decrease bacterial load of <i>Salmonella</i> in mammalian cells. by Abigail L. Reens (5349746)

<i>dVMAT</i> mutants show decreased histamine labeling in subretinal glia. by Rafael Romero-Calderón (170680)

“…Note that labeling of the retina is less evident in these cryostat sections compared with that in the confocal stacks shown in (A–G). (I) <i>dVMAT</i>^Δ14 shows a decrease in labeling in the distal lamina relative to <i>w—</i>compare (H) and (I) (large arrows). …”

Decrease of 4 Asp isomers at 70°C. by Kenzo Aki (386666)

“…<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058515#pone-0058515-g007" target="_blank">Figure 7a:</a> decrease of L-α-Asp with incubation of T6-Lα peptide at 70°C. …”

The Intestine Nucleus and Seam Cell Number Decreased in <i>fw8</i> Mutants. by Xiangming Wang (372213)

“…<p>(A) The <i>rrIs1</i> [P<i>elt-2::GFP</i>] marker visualizes the nuclei of the intestine cells. …”

Zebrafish harboring homozygous mutations in <i>gdf6</i> exhibit decreased endurance. by Michèle G. DuVal (278183)

“…<p><b>A. </b><i>gdf6^−/−</i> fish have a lower endurance compared to <i>gdf6^+/+</i> siblings as measured by increasing water velocity in a swim channel to determine the <i>U</i>_crit i.e. …”

Demonstration of the effects of decreased size at metamorphosis on amphibians by Tyrone B. Hayes (29098)