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The role of soluble uric acid in modulating autophagy flux and inflammasome activation during bacterial infection in macrophages
Published 2020“…We observed that IL-1β increased during bacterial infection but decreased when macrophages were co-stimulated with bacteria and uric acid. …”
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MYD88, IRAK3 and Rheumatoid Arthritis pathogenesis: Analysis of differential gene expression in CD14 + monocytes and the inflammatory cytokine levels.
Published 2021“…Rheumatoid arthritis (RA) is a well-known chronic inflammatory disorder. Two molecular players act in the inflammation balance of the disease: MyD88 (Myeloid differentiation primary response 88) is related to TLR (Toll-like receptors) response and promotes the formation of myddosome complex resulting in increased inflammation; IRAK3 (Interleukin-1 receptor associated kinase 3) acts suppressing the myddosome complex thus decreasing inflammation. …”
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A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge
Published 2021“…Distal necrosis of the patients in this study patients was compared with that in a control of 10 patients in whom we did the conventional FDMA flap. …”
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Chronic melatonin treatment improves obesity by inducing uncoupling of skeletal muscle SERCA-SLN mediated by CaMKII/AMPK/PGC1α pathway and mitochondrial biogenesis in female and ma...
Published 2024“…Obese ZDF rats and lean littermates (ZL) of both sexes were subdivided into two subgroups: control (C) and 12 weeks orally melatonin treated (M) (10 mg/kg/day). Compared to the control groups, melatonin decreased the body weight gain and visceral fat in ZDF rats of both sexes. …”
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A rare loss-of-function genetic mutation suggest a role of dermcidin deficiency in hidradenitis suppurativa pathogenesis
Published 2022“…Focusing on rare damaging variants, we identified a rare insertion of one nucleotide (c.225dupA:p.A76Sfs*21) in the DCD gene encoding for the antimicrobial peptide dermcidin (DCD) that was shared by the proband, his affected father and his 11-years old daughter. …”
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Studying movement reorganization when learning a whole-body action: Example of learning a constrained gait pattern
Published 2015“…Results indicated an immediate reorganization incoordinative patterns (e.g., relative phases and stride frequency) accompanied by a general decrease in the initial movement variability (i.e., standard deviation of many key variables). …”
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Service Ethnocentrism: A Conceptual Model (An Abstract)
Published 2017“…In this model, we have identified factors that lead to an increase in SE and other factors that lead to a decrease in SE. …”
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A novel index based on planktonic copepod reproductive traits as a tool for marine ecotoxicology studies
Published 2020“…However, the response to Persistent Organic Pollutants (POPs) such as pentachlorophenol (PCP) and 1,2-dichlorobenzene (DCB) differs. In E. affinis, EPR increases with DCB, but HS falls to <1%. …”
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Interfaces study of all-polysaccharide composite films
Published 2018“…The lowest OT temperature was observed at QC/X = 1/3. We think it is due to the thermocatalytic effect of the 4-O-methyl-D-glucuronate in X and the QC quaternary groups on the thermolysis–thermo-oxidation mechanism. …”
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